mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2021-1-94-97mrj-1106Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL OBSERVATIONSAvascular Necrosis of the Foot and Ankle in a Patient with Systemic Sclerosis: A Case Based ReviewAvascular Necrosis of the Foot and Ankle in a Patient with Systemic Sclerosis: A Case Based Reviewhttps://orcid.org/0000-0001-7708-4167WastynH.WastynH.

Heline Wastyn

Medical Student, Faculty of Medicine

Preshoekstraat 33, 8930 Lauwe, Belgium

Heline Wastyn

Medical Student, Faculty of Medicine

Preshoekstraat 33, 8930 Lauwe, Belgium

heline.wastyn@student.kuleuven.beLeysМ.LeysM.

Mathias Leys, M.D.   

Department of Pneumology

 

Mathias Leys, M.D. 

Department of Pneumology

MichelsF.MichelsF.

Frederick Michels, M.D.

Department of Orthopedics and Traumatology

Frederick Michels, M.D.

Department of Pneumology

DeleuА.-L.DeleuA.-L.

Anne-Leen Deleu, M.D.

Resident in Department of Nuclear Medicine

Anne-Leen Deleu, M.D.

Resident in Department of Nuclear Medicine

VereeckeЕ.VereeckeE.

Evie Vereecke, prof.

Department of Development and Regeneration

Evie Vereecke, prof.

Department of Development and Regeneration

MatricaliG.MatricaliG.

Giovanni Matricali, prof., M.D., PhD

Department of Orthopedic Surgery University Hospitals Leuven

Department of Development and Regeneration, KU Leuven

Leuven, Heverlee

Giovanni Matricali, prof., M.D., PhD

Department of Orthopedic Surgery University Hospitals Leuven

Department of Development and Regeneration, KU Leuven

Leuven, Heverlee

ClockaertsS.ClockaertsS.

Stefan Clockaerts, M.D.

Foot and Ankle Unit, Department of Orthopedics and Traumatology, AZ Sint-Maarten Mechelen

Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, KU Leuven

Stefan Clockaerts, M.D.

Foot and Ankle Unit, Department of Orthopedics and Traumatology, AZ Sint-Maarten Mechelen

Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, KU Leuven

KU LeuvenБельгияKU LeuvenBelgiumAZ Groeninge KortrijkБельгияAZ Groeninge KortrijkBelgiumKulak Kortrijk CampusБельгияKulak Kortrijk CampusBelgiumUniversity Hospitals Leuven; KU Leuven; Institute of Orthopaedic Research & Training (IORT)БельгияUniversity Hospitals Leuven; KU Leuven; Institute of Orthopaedic Research & Training (IORT)BelgiumAZ Sint-Maarten Mechelen; KU LeuvenБельгияAZ Sint-Maarten Mechelen; KU LeuvenBelgium2021180220211519497Copyright © Wastyn H., Leys М., Michels F., Deleu А., Vereecke Е., Matricali G., Clockaerts S., 20212021Wastyn H., Leys М., Michels F., Deleu А., Vereecke Е., Matricali G., Clockaerts S.Wastyn H., Leys M., Michels F., Deleu A., Vereecke E., Matricali G., Clockaerts S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1106

This review describes a case of atraumatic avascular necrosis in the foot and ankle in a patient with systemic sclerosis who did not receive corticosteroid therapy. Both avascular necrosis and systemic sclerosis are uncommon disease entities. This case demonstrates that vasculitis and secondary vasoconstriction in the pathogenesis of systemic sclerosis are important risk factors for the development of avascular necrosis of the foot and ankle. Therefore, if these patients develop chronic foot and ankle pain, avascular necrosis should be included in the differential diagnosis, even if they do not receive corticosteroids. For the diagnosis and follow-up of avascular necrosis MRI remains the gold standard. Thus, MRI should be used to diagnose avascular necrosis in an early stage. Level of Clinical Evidence: 4.

This review describes a case of atraumatic avascular necrosis in the foot and ankle in a patient with systemic sclerosis who did not receive corticosteroid therapy. Both avascular necrosis and systemic sclerosis are uncommon disease entities. This case demonstrates that vasculitis and secondary vasoconstriction in the pathogenesis of systemic sclerosis are important risk factors for the development of avascular necrosis of the foot and ankle. Therefore, if these patients develop chronic foot and ankle pain, avascular necrosis should be included in the differential diagnosis, even if they do not receive corticosteroids. For the diagnosis and follow-up of avascular necrosis MRI remains the gold standard. Thus, MRI should be used to diagnose avascular necrosis in an early stage. Level of Clinical Evidence: 4.

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The authors declare that there are no conflicts of interest present.