mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2021-4-72-80mrj-1174Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCLINICAL OBSERVATIONSСочетание анкилозирующего спондилита и ревматоидного артрита: клинические наблюдения и обзор литературыCombination of ankylosing spondylitis and rheumatoid arthritis: clinical observations and literature reviewhttps://orcid.org/0000-0002-5493-6045ГодзенкоА. А.GodzenkoA. A.

Алла Александровна Годзенко

Кафедра ревматологии

125993, Москва, ул. Баррикадная, 2/1, стр. 1115522, Москва, Каширское шоссе, 34А

Alla Alexandrovna Godzenko

Department of Rheumatology

2/1, Barrikadnaya St., Build. 1, Moscow 12599334A, Kashirskoe Shosse, Moscow 115522

alla1106@mail.ruhttps://orcid.org/0000-0002-4383-9872ЧеремушкинаЕ. В.CheremushkinaE. V.

Кафедра ревматологии

125993, Москва, ул. Баррикадная, 2/1, стр. 1

Department of Rheumatology

2/1, Barrikadnaya St., Build. 1, Moscow 125993

https://orcid.org/0000-0001-7353-4087ДимитреваА. Е.DimitrevaA. E.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

https://orcid.org/0000-0002-9755-5760УрумоваМ. М.UrumovaM. M.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»; ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияRussian Medical Academy of Continuing Professional Education; V.A. Nasonova Research Institute of RheumatologyRussian FederationФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»РоссияRussian Medical Academy of Continuing Professional EducationRussian FederationФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation2021140820211547280Copyright © Годзенко А.А., Черемушкина Е.В., Димитрева А.Е., Урумова М.М., 20212021Годзенко А.А., Черемушкина Е.В., Димитрева А.Е., Урумова М.М.Godzenko A.A., Cheremushkina E.V., Dimitreva A.E., Urumova M.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1174

В статье рассмотрен один из вариантов перекрестных (overlap) синдромов – сочетание симптоматики анкилозирующего спондилита (АС) и ревматоидного артрита (РА). Описаны три клинических наблюдения, в которых отмечались характерные признаки обоих заболеваний и соответствие критериям обоих диагнозов. Проанализированы генетические факторы и иммунопатогенетические механизмы, лежащие в основе АС и РА. Представлен обзор литературы, посвященной сочетанию АС и РА.

The article discusses one of the variants of overlap syndrome – a combination of symptoms of ankylosing spondylitis (AS) and rheumatoid arthritis (RA). Three clinical cases are described, in these cases characteristic signs of both diseases were noted and the criteria of both diseases were met. The genetic factors and immunopathogenetic mechanisms underlying AS and RA are analyzed. A review of the literature on the combination of AS and RA is presented.

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The authors declare that there are no conflicts of interest present.