mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2021-4-101-106mrj-1178Research ArticleОБЗОРЫREVIEWSОценка активности и повреждения органов при антифосфолипидном синдромеAssessment of the activity and organ damage in antiphospholipid syndromehttps://orcid.org/0000-0001-5217-4932ЧельдиеваФ. А.CheldievaF. A.

кафедра ревматологии

115522, Москва, Каширское шоссе, 34А125993, Москва, ул. Баррикадная, 2/1, стр. 1

Department of Rheumatology

34A, Kashirskoe Shosse, Moscow 1155222/1, Barrikadnaya St., Build. 1, Moscow 125993

https://orcid.org/0000-0003-3552-2522РешетнякТ. М.ReshetnyakT. M.

Татьяна Магомедалиевна Решетняк

кафедра ревматологии

115522, Москва, Каширское шоссе, 34А125993, Москва, ул. Баррикадная, 2/1, стр. 1

Tatiana Magomedalievna Reshetnyak

Department of Rheumatology

34A, Kashirskoe Shosse, Moscow 1155222/1, Barrikadnaya St., Build. 1, Moscow 125993

reshetnyak@yahoo.comhttps://orcid.org/0000-0002-6068-3080ЛилаА. М.LilaA. M.

кафедра ревматологии

115522, Москва, Каширское шоссе, 34А125993, Москва, ул. Баррикадная, 2/1, стр. 1

Department of Rheumatology

34A, Kashirskoe Shosse, Moscow 1155222/1, Barrikadnaya St., Build. 1, Moscow 125993

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional EducationRussian Federation202115082021154101106Copyright © Чельдиева Ф.А., Решетняк Т.М., Лила А.М., 20212021Чельдиева Ф.А., Решетняк Т.М., Лила А.М.Cheldieva F.A., Reshetnyak T.M., Lila A.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1178

В обзоре приведена краткая характеристика клинических и серологических маркеров антифосфолипидного синдрома (АФС), факторов риска развития и рецидивирования тромбозов при АФС. Представлено полное описание шкалы оценки активности АФС – GAPSS и ее упрощенной (скорректированной) версии – adjusted GAPSS (aGAPSS), а также индекса повреждения для АФС – DIAPS. Эти шкалы позволяют определить активность АФС и отражают диапазон кумулятивного и/или необратимого ущерба заболевания.

The review provides a brief description of the clinical and serological markers of antiphospholipid syndrome (APS), risk factors for the development and recurrence of thrombosis in APS. A complete description of the GAPSS and its simplified (corrected) version, adjusted GAPSS (aGAPSS), as well as the DIAPS, is presented. These scales allow one to determine the activity of APS and reflect the range of cumulative and/or irreversible damage due to the disease.

антифосфолипидный синдромшкала глобальной оценки активности антифосфолипидного синдрома (GAPSS)индекс повреждения антифосфолипидного синдрома (DIAPS)antiphospholipid syndromeGlobal Antiphospholipid Syndrome Score (GAPSS)antiphospholipid syndrome damage index (DIAPS)Работа подготовлена в рамках темы «Разработка методов персонифицированной терапии ревматических заболеваний с коморбидной патологией» (АААА-А19-119021190151-3).The investigation has been conducted within scientific topic «Development of methods for personalized therapy of rheumatic diseases with comorbid pathology» (№АААА-А19-119021190151-3).ReferencesРешетняк ТМ. Антифосфолипидный синдром: диагностика и клинические проявления (лекция). Научно-практическая ревматология. 2014;52(1):56-71.Reshetnyak TM. Antiphospholipid syndrome: diagnosis and clinical manifestations (a lecture). Nauchno-prakticheskaya revmatologiya. 2014; 52 (1):56–71. (In Russ.).Miyakis S, Lockshin MD, Atsumi T, et al. 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The authors declare that there are no conflicts of interest present.