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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2021-5-51-56</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1197</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Определение точности оценки риска возникновения остеопоротических переломов у больных ревматоидным артритом с использованием прогностической модели, разработанной в ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», и алгоритма FRAX</article-title><trans-title-group xml:lang="en"><trans-title>Determination of the accuracy of osteoporotic fractures risk assessment in patients with rheumatoid arthritis using the prognostic model, developed at V.A. Nasonova Research Institute of Rheumatology, and the FRAX algorithm</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4600-7534</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кожевникова</surname><given-names>П. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozhevnikova</surname><given-names>P. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полина Олеговна Кожевникова</p><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>Polina Olegovna Kozhevnikova</p><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><email xlink:type="simple">pko31@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6076-4374</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваленко</surname><given-names>П. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalenko</surname><given-names>P. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2985-8831</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дыдыкина</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Dydykina</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4285-0869</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глухова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Glukhova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6068-3080</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p><p>2/1, Barrikadnaya Street, Build. 1, Moscow 125993</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; Кафедра ревматологии ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2021</year></pub-date><volume>15</volume><issue>5</issue><fpage>51</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кожевникова П.О., Коваленко П.С., Дыдыкина И.С., Глухова С.И., Лила А.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кожевникова П.О., Коваленко П.С., Дыдыкина И.С., Глухова С.И., Лила А.М.</copyright-holder><copyright-holder xml:lang="en">Kozhevnikova P.O., Kovalenko P.S., Dydykina I.S., Glukhova S.I., Lila A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1197">https://mrj.ima-press.net/mrj/article/view/1197</self-uri><abstract><p>Цель исследования – сравнение точности оценки риска возникновения низкоэнергетических переломов у больных ревматоидным артритом (РА) с использованием прогностической модели, разработанной в ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой» (НИИР им. В.А. Насоновой), и российской модели алгоритма FRAX.Пациенты и методы. В проспективное многолетнее наблюдательное неинтервенционное исследование было включено 70 женщин в возрасте 40–80 лет с достоверным диагнозом РА (АCR, 1987). У всех больных исходно и в динамике проведена двухэнергетическая рентгеновская абсорбциометрия, проанализированы клинико-анамнестические данные, в том числе сведения о переломах, произошедших за период наблюдения, подтвержденных медицинскими документами.Результаты и обсуждение. Чувствительность и специфичность алгоритма FRAX составили 67 и 56%, чувствительность и специфичность прогностической модели НИИР им. В.А. Насоновой – 78 и 56% соответственно. Диагностическая точность алгоритма FRAX и прогностической модели находились на уровне 58 и 61% соответственно.Заключение. Прогностическая модель, разработанная в НИИР им. В.А. Насоновой, показала более высокие диагностическую точность и чувствительность, а также сопоставимую специфичность с алгоритмом FRAX при оценке переломов у больных РА.</p></abstract><trans-abstract xml:lang="en"><p>Objective: comparison of the accuracy of risk assessment of low-energy fractures in patients with rheumatoid arthritis (RA) using the prognostic model developed at V.A. Nasonova Research Institute of Rheumatology, and the Russian model of the FRAX algorithm.Patients and methods. A prospective long-term observational non-interventional study included 70 women aged 40–80 years with a definite diagnosis of RA (ACR, 1987). All patients underwent dual-energy X-ray absorptiometry at baseline and over time; clinical and anamnestic data were analyzed, including information on fractures that occurred during the observation period, confirmed by medical documents.Results and discussion. The sensitivity and specificity of the FRAX algorithm were 67 and 56%, the sensitivity and specificity of the prognostic model of V.A. Nasonova Research Institute of Rheumatology – 78 and 56%, respectively. The diagnostic accuracy of the FRAX algorithm and the predictive model was 58 and 61%, respectively.Conclusion. The predictive model developed at V.A. Nasonova Research Institute of Rheumatology, showed higher diagnostic accuracy and sensitivity, as well as comparable specificity with the FRAX algorithm in assessing fractures in RA patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматоидный артрит</kwd><kwd>FRAX</kwd><kwd>остеопороз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatoid arthritis</kwd><kwd>FRAX</kwd><kwd>osteoporosis</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено в рамках поискового научного исследования «Ревматоидный артрит и коморбидная патология: диагностика и персонифицированная терапии» (AAAA-A20-120040190015-5, 0397-2020-0002).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, редактор. Российские клинические рекомендации. Ревматология. 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