mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2022-1-103-107mrj-1260Research ArticleОБЗОРЫREVIEWSТерапия нестероидными противовоспалительными препаратами и качество жизни пациентов с ревматическими заболеваниямиTherapy with non-steroidal anti-inflammatory drugs and the quality of life of patients with rheumatic diseaseshttps://orcid.org/0000-0001-5103-5447ПолищукЕ. Ю.PolishchukE. Yu.

Елена Юрьевна Полищук

115522, Москва, Каширское шоссе, 34А

Elena Yurievna Polishchuk

34A, Kashirskoe shosse, Moscow 115522

dr.pogozheva@gmail.comhttps://orcid.org/0000-0002-1391-0711КаратеевА. Е.KarateevA. E.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe shosse, Moscow 115522

https://orcid.org/0000-0001-5382-6357АмирджановаВ. Н.AmirdzhanovaV. N.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe shosse, Moscow 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation202219022022161103107Copyright © Полищук Е.Ю., Каратеев А.Е., Амирджанова В.Н., 20222022Полищук Е.Ю., Каратеев А.Е., Амирджанова В.Н.Polishchuk E.Y., Karateev A.E., Amirdzhanova V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1260

Современная стратегия терапии ревматических заболеваний (РЗ) предполагает максимально быстрое достижение ремиссии или низкой активности заболевания. Однако даже при использовании самых современных технологий и выраженном снижении воспалительной активности заболевания не всегда удается достигнуть полной и стойкой ремиссии. В подобной ситуации важной задачей лечения является максимальное улучшение качества жизни (КЖ) пациентов. Боль – один из ведущих предикторов снижения показателей КЖ у пациентов с РЗ. При этом действенный контроль боли способен улучшить не только течение отдельных симптомов болезни, но и жизненный прогноз в целом. Нестероидные противовоспалительные препараты (НПВП) являются наиболее востребованными средствами для симптоматического лечения РЗ. При этом назначение НПВП с благоприятным профилем безопасности позволяет улучшить КЖ больных. Мелоксикам – первый преимущественно селективный ингибитор циклооксигеназы (ЦОГ) 2, появившийся в арсенале практических врачей еще в конце 90-х годов и имеющий серьезную доказательную базу эффективности и безопасности.

The modern strategy for the treatment of rheumatic diseases (RD) involves the fastest possible achievement of remission or low disease activity. However, even with the use of the most modern technologies and after a pronounced decrease in the inflammatory activity of the disease, it is not always possible to achieve a complete and stable remission. In such a situation, an important goal of treatment is to maximize the quality of life (QoL) of patients. Pain is one of the leading predictors of a decrease in QoL in patients with RD. At the same time, effective pain control can improve not only the course of individual symptoms of the disease, but also life prognosis as a whole. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most popular drugs for the symptomatic treatment of RD. At the same time, the administration of NSAIDs with a favorable safety profile can improve the quality of life of patients. Meloxicam is the first predominantly selective inhibitor of cyclooxygenase (COX) 2, which appeared in the arsenal of practitioners in the late 90s and has a strong evidence base for efficacy and safety.

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The authors declare that there are no conflicts of interest present.