mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2022-3-7-13mrj-1291Research ArticleЛЕКЦИИLECTURESПоражение кожи при системной красной волчанке. Часть 1: классификация, этиология, патогенезSkin lesions in systemic lupus erythematosus. Part 1: classification, etiology, pathogenesishttps://orcid.org/0000-0003-1318-1894ШумиловаА. А.ShumilovaA. A.

Анастасия Александровна Шумилова

115522, Москва, Каширское шоссе, 34А

Anastasia Aleksandrovna Shumilova

134A, Kashirskoe shosse, Moscow 115522

dr.anashumilova@gmail.comhttps://orcid.org/0000-0002-6399-8766ТравкинаЕ. И.TravkinaE. I.

115522, Москва, Каширское шоссе, 34А

134A, Kashirskoe shosse, Moscow 115522

https://orcid.org/0000-0003-3552-2522РешетнякТ. М.ReshetnyakT. M.

115522, Москва, Каширское шоссе, 34А

125993, Москва, ул. Баррикадная, 2/1, стр. 1

134A, Kashirskoe shosse, Moscow 115522

Barrikadnaya street, building 1, Moscow 125993

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian FederationФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; кафедра ревматологии ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияV.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional EducationRussian Federation202217062022163713Copyright © Шумилова А.А., Травкина Е.И., Решетняк Т.М., 20222022Шумилова А.А., Травкина Е.И., Решетняк Т.М.Shumilova A.A., Travkina E.I., Reshetnyak T.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1291

Поражение кожи и слизистых оболочек при системной красной волчанке (СКВ), хотя и не является грозным симптомом, значительно ухудшает качество жизни пациентов. Кожные проявления СКВ могут возникать как в дебюте заболевания, так и в более позднем периоде. Хотя в последних классификационных критериях СКВ изменения кожи и слизистых оболочек четко сгруппированы, верификация диагноза требует многопрофильного подхода. В этиологии СКВ играют роль факторы внешней среды, гормональные нарушенния, генетическая предрасположенность. Дальнейшие исследования позволят обнаружить различия в подтипах кожной красной волчанки и будут способствовать разработке новых методов терапии.

Skin and mucous membranes lesions in systemic lupus erythematosus (SLE) significantly impair the quality of life of patients, although they are not a formidable manifestation of the disease. Skin manifestations of SLE can occur both at the onset and on the late stage of the disease. Although skin and mucous membranes lesions are clearly grouped in the latest classification criteria for SLE, verification of the diagnosis requires a multidisciplinary approach. In the etiology of SLE, environmental factors, hormonal factors, and genetic predisposition play a role. Further research will reveal differences in subtypes of cutaneous lupus erythematosus and will facilitate the development of new therapies.

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The authors declare that there are no conflicts of interest present.