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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2022-3-50-59</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1297</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Особенности гериатрического статуса у пожилых пациентов с остеоартритом в сочетании с невропатической болью: данные российского эпидемиологического исследования ЭВКАЛИПТ</article-title><trans-title-group xml:lang="en"><trans-title>Features of geriatric status in elderly patients with osteoarthritis combined with neuropathic pain: data from the Russian epidemiological study EVKALIPT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6253-621X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наумов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Naumov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Антон Вячеславович Наумов</p><p>129226, Москва, ул. 1-я Леонова, 16</p><p>117997, Москва, ул. Островитянова 1</p></bio><bio xml:lang="en"><p>Anton Vyacheslavovich Naumov</p><p>116, 1st Leonova street, Moscow 129226</p><p>1, Ostrovityanova street, Moscow117997</p></bio><email xlink:type="simple">nanton78@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6021-7864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьева</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobieva</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129226, Москва, ул. 1-я Леонова, 16</p></bio><bio xml:lang="en"><p>116, 1st Leonova street, Moscow 129226</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3066-4866</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ховасова</surname><given-names>Н. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Khovasova</surname><given-names>N. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129226, Москва, ул. 1-я Леонова, 16</p><p>117997, Москва, ул. Островитянова 1</p></bio><bio xml:lang="en"><p>116, 1st Leonova street, Moscow 129226</p><p>1, Ostrovityanova street, Moscow117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4193-688X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129226, Москва, ул. 1-я Леонова, 16</p><p>117997, Москва, ул. Островитянова 1</p></bio><bio xml:lang="en"><p>116, 1st Leonova street, Moscow 129226</p><p>1, Ostrovityanova street, Moscow117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1628-5093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котовская</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotovskaya</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129226, Москва, ул. 1-я Леонова, 16</p></bio><bio xml:lang="en"><p>16, 1st Leonova street, Moscow 129226</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6623-6815</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селезнева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Selezneva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>109028, Москва, Покровский бульвар, 11</p></bio><bio xml:lang="en"><p>11, Pokrovskiy boulevard, Moscow 109028</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7266-707X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овчарова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovcharova</surname><given-names>L. H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>109028, Москва, Покровский бульвар, 11</p></bio><bio xml:lang="en"><p>11, Pokrovskiy boulevard, Moscow 109028</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ОСП «Российский геронтологический научно-клинический центр» и кафедра болезней старения ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University; Department of age diseases, N.I. Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ОСП «Российский геронтологический научно-клинический центр»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Clinical and Research Center of Gerontology, N.I. Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Национальный исследовательский университет «Высшая школа экономики»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research University “Higher School of Economics”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>19</day><month>06</month><year>2022</year></pub-date><volume>16</volume><issue>3</issue><fpage>50</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Наумов А.В., Воробьева Н.М., Ховасова Н.О., Ткачева О.Н., Котовская Ю.В., Селезнева Е.В., Овчарова Л.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Наумов А.В., Воробьева Н.М., Ховасова Н.О., Ткачева О.Н., Котовская Ю.В., Селезнева Е.В., Овчарова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Naumov A.V., Vorobieva N.M., Khovasova N.O., Tkacheva O.N., Kotovskaya Y.V., Selezneva E.V., Ovcharova L.H.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1297">https://mrj.ima-press.net/mrj/article/view/1297</self-uri><abstract><p>Главные симптомы остеоартрита (ОА) – боль и нарушение функции суставов. Невропатическая боль (НБ) встречается более чем у половины больных ОА, носит рефрактерный характер и является причиной более частого обращения за медицинской помощью, низкого качества жизни и инвалидизации.Цель исследования – оценить частоту НБ и ее взаимосвязь с гериатрическими синдромами (ГС) у пациентов с ОА в возрасте 65 лет и старше.Пациенты и методы. В субанализ исследования ЭВКАЛИПТ включено 2286 пациентов с ОА и хроническим болевым синдромом. Всем больным проведены комплексная гериатрическая оценка (КГО) и диагностика НБ с помощью опросника DN4.Результаты и обсуждение. Распространенность НБ у пациентов с ОА составила 22,7%. Пациенты с ОА и НБ чаще испытывали боль любой локализации с большим количеством болевых точек, у них были выше частота и интенсивность болевого синдрома, они чаще принимали анальгетики и отмечали ограничения в повседневной жизни. При проведении корреляционного анализа обнаружены взаимосвязи средней силы между суммой баллов по опроснику DN4 и оценкой интенсивности боли по числовой рейтинговой шкале в момент осмотра (r=0,26; p&lt;0,001) и в предшествующие 7 дней (r=0,29; p&lt;0,001). Данные КГО у пациентов с ОА и НБ продемонстрировали худший гериатрический статус и более высокую частоту ГС. Наиболее распространенными ГС были базовая (81%) и инструментальная (64%) зависимость в повседневной жизни, старческая астения (70%), недержание мочи (69%), депрессия (69%) и когнитивные нарушения (67%). Многофакторный анализ показал, что с наличием НБ, помимо возраста, независимо ассоциированы сенсорный дефицит, депрессия, падения, недержание мочи и пролежни (отношение шансов 1,77–2,49). Пациенты с НБ чаще использовали вспомогательные средства для облегчения мобильности, абсорбирующее белье и ортопедические изделия.Заключение. НБ диагностирована у 22,7% пациентов с ОА в возрасте 65 лет и старше. Такие больные имеют худший функциональный статус, у них чаще диагностируется ряд ГС.</p></abstract><trans-abstract xml:lang="en"><p>The main symptoms of osteoarthritis (OA) are pain and dysfunction of the joints. Neuropathic pain (NP) occurs in more than half of patients with OA, it is refractory in nature and is the cause for seeking medical advice more frequently, poor quality of life and disability.Objective: to evaluate the frequency of NP and its relationship with geriatric syndromes (GS) in patients with OA aged 65 years and older. Patients and methods. The subanalysis of the study EVKALIPT included 2286 patients with OA and chronic pain syndrome. All patients underwent a comprehensive geriatric assessment (CGA) and diagnostics of NP using the DN4 questionnaire.Results and discussion. The prevalence of NP in patients with OA was 22.7%. Patients with OA and NP more often experienced pain of any localization with a large number of tender points, they had a higher frequency and intensity of pain syndrome, they more often took analgesics and noted limitations in daily life. When conducting a correlation analysis, correlations of medium strength were found between the sum of scores according to DN4 questionnaire and the pain intensity assessment on a numerical rating scale at the time of examination (r=0.26; p&lt;0.001) and in the previous 7 days (r=0.29; p&lt;0.001). CGA data in patients with OA and NP demonstrated worse geriatric status and a higher incidence of GS. The most common GSs were basic (81%) and instrumental (64%) dependence in everyday life, senile asthenia (70%), urinary incontinence (69%), depression (69%) and cognitive impairment (67%). Multivariate analysis showed that, in addition to age, the presence of NP was independently associated with sensory deficits, depression, falls, urinary incontinence, and bedsores (odds ratio 1.77–2.49). Patients with NP were more likely to use mobility aids, absorbent underwear, and orthotics.Conclusion. NP was diagnosed in 22.7% of OA patients aged 65 years and older. Such patients have worse functional status, they are more often diagnosed with a number of GSs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>остеоартрит</kwd><kwd>хроническая боль</kwd><kwd>невропатическая боль</kwd><kwd>гериатрические синдромы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteoarthritis</kwd><kwd>chronic pain</kwd><kwd>neuropathic pain</kwd><kwd>geriatric syndromes</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено в рамках Государственного задания «Оптимизация диагностики и ведения сочетанных заболеваний опорно-двигательного аппарата у пациентов пожилого и старческого возраста с целью сохранения автономности» №69.7-2021.</funding-statement><funding-statement xml:lang="en">The investigation has been conducted as part of government program "Optimization of diagnosis and management of combined diseases of the musculoskeletal system in elderly and senile patients in order to maintain autonomy" №69.7-2021.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hawker GA. 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