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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-70122022-6-80-83</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1376</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Развитие двустороннего эписклерита и ревматоидного артрита после перенесенной новой коронавируснои инфекции: описание клинического случая</article-title><trans-title-group xml:lang="en"><trans-title>Development of bilateral episcleritis and rheumatoid arthritis after a new coronavirus infection: a description of a clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4504-6630</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матвеева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Matveeva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матвеева Ольга Николаевна.</p><p>344019, Ростов-на-Дону, ул. 13-я Линия, 8</p></bio><bio xml:lang="en"><p>Olga N. Matveeva.</p><p>8, 13th Liniya Street, Rostov-on-Don 344019</p></bio><email xlink:type="simple">olgamv29@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8707-1458</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Квасова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kvasova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>344011, Ростов-на-Дону, пер. Доломановский, 70/3</p></bio><bio xml:lang="en"><p>70/3, Dolomanovsky Alley, Rostov-on-Don 344011</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МЦ «Гиппократ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Hippocrates Medical Center Ltd</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Клинико-диагностическй центр «Здоровье»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Diagnostic Center "Zdorovie"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>18</day><month>12</month><year>2022</year></pub-date><volume>16</volume><issue>6</issue><fpage>80</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Матвеева О.Н., Квасова Е.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Матвеева О.Н., Квасова Е.В.</copyright-holder><copyright-holder xml:lang="en">Matveeva O.N., Kvasova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1376">https://mrj.ima-press.net/mrj/article/view/1376</self-uri><abstract><p>В декабре 2019 г. мир столкнулся с новым инфекционным заболеванием, получившим название новой коронавирусной болезни 2019 (COVID-19), масштабы распространения которой приобрели характер пандемии. Инфекция, остающаяся с нами и по сей день, может вызывать очень тяжелые респираторные симптомы вплоть до тотального поражения легких и смерти, а также серьезные системные проявления, связанные с чрезмерной активацией иммунных механизмов. В настоящее время известно множество случаев вторичных аутоиммунных процессов, нередко формирующих полноценные аутоиммунные заболевания у лиц, перенесших новую коронавирусную инфекцию.</p><p>Представлено клиническое наблюдение, в котором на фоне перенесенного COVID-19 развился эписклерит, а затем и суставной синдром, соответствующий классификационным критериям ревматоидного артрита. Обсуждаются необычность дебюта суставного синдрома у данного пациента, трудности ранней диагностики заболевания, а также возможные механизмы формирования подобных ассоциаций.</p></abstract><trans-abstract xml:lang="en"><p>In December 2019, the world faced a new infectious disease, called the novel coronavirus disease 2019 (COVID-19), whose spread has become pandemic. The infection that remains with us to the present day can cause very severe respiratory symptoms up to total lung damage and death, as well as serious systemic manifestations associated with excessive activation of immune mechanisms. Currently, there are many cases of secondary autoimmune processes, often forming full-fledged autoimmune diseases, in people who have had a new coronavirus infection.</p><p>We present a clinical observation of episcleritis developed on the background of COVID-19, and then an articular syndrome onset that met the classification criteria for rheumatoid arthritis. The unusual debut of the articular syndrome in this patient, the difficulties of early diagnosis of the disease, as well as possible mechanisms of the formation of such associations are discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>SARS-CoV-2</kwd><kwd>COVID-19</kwd><kwd>эписклерит</kwd><kwd>ревматоидный артрит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>SARS-CoV-2</kwd><kwd>COVID-19</kwd><kwd>episcleritis</kwd><kwd>rheumatoid arthritis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020 Feb 15;395(10223): 470-3. doi: 10.1016/S0140-6736(20)30185-9. Epub 2020 Jan 24.</mixed-citation><mixed-citation xml:lang="en">Wang C, Horby PW, Hayden FG, Gao GF. A novel coronavirus outbreak of global health concern. Lancet. 2020 Feb 15;395(10223): 470-3. doi: 10.1016/S0140-6736(20)30185-9. Epub 2020 Jan 24.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sedaghat Z, Karimi N. Guillain Barre syndrome associated with COVID-19 infection: A case report. J Clin Neurosci. 2020 Jun; 76:233-5. doi: 10.1016/j.jocn.2020.04.062. Epub 2020 Apr 15.</mixed-citation><mixed-citation xml:lang="en">Sedaghat Z, Karimi N. Guillain Barre syndrome associated with COVID-19 infection: A case report. J Clin Neurosci. 2020 Jun; 76:233-5. doi: 10.1016/j.jocn.2020.04.062. Epub 2020 Apr 15.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Егорова ОН, Голоева РГ, Абдулганиева ДИ. Септальный панникулит как проявление COVID-19: собственные данные. Современная ревматология. 2021; 15(4):31-7. doi: 10.14412/1996-7012-2021-4-31-37</mixed-citation><mixed-citation xml:lang="en">Egorova ON, Goloeva RG, Abdulganieva DI. Septal panniculitis as manifestation of COVID-19: own data. Sovremennaya revmatologiya = Modern Rheumatology Journal. 2021;15(4):31-7. (In Russ.). doi: 10.14412/1996-7012-2021-4-31-37</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gasparotto M, Framba V, Piovella C, et al. Post-COVID-19 arthritis: a case report and literature review. Clin Rheumatol. 2021 Aug; 40(8):3357-62. doi: 10.1007/s10067-020-05550-1. Epub 2021 Feb 15.</mixed-citation><mixed-citation xml:lang="en">Gasparotto M, Framba V, Piovella C, et al. Post-COVID-19 arthritis: a case report and literature review. Clin Rheumatol. 2021 Aug; 40(8):3357-62. doi: 10.1007/s10067-020-05550-1. Epub 2021 Feb 15.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Parisi S, Borrelli R, Bianchi S, Fusaro E. Viral arthritis and COVID-19. Lancet Rheumatol. 2020 Nov;2(11):e655-e657. doi: 10.1016/S2665-9913(20)30348-9. Epub 2020 Oct 5.</mixed-citation><mixed-citation xml:lang="en">Parisi S, Borrelli R, Bianchi S, Fusaro E. Viral arthritis and COVID-19. Lancet Rheumatol. 2020 Nov;2(11):e655-e657. doi: 10.1016/S2665-9913(20)30348-9. Epub 2020 Oct 5.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Viner RM, Whittaker E. Kawasaki-like disease: emerging complication during the COVID-19 pandemic. Lancet. 2020 Jun 6; 395(10239):1741-3. doi: 10.1016/S0140-6736(20)31129-6. Epub 2020 May 13.</mixed-citation><mixed-citation xml:lang="en">Viner RM, Whittaker E. Kawasaki-like disease: emerging complication during the COVID-19 pandemic. Lancet. 2020 Jun 6; 395(10239):1741-3. doi: 10.1016/S0140-6736(20)31129-6. Epub 2020 May 13.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Каратеев ДЕ, Олюнин ЮА, Лучихина ЕЛ. Новые классификационные критерии ревматоидного артрита ACR/EULAR 2010 -шаг вперед к ранней диагностике. Научно-практическая ревматология. 2011; 49(1):10-5.</mixed-citation><mixed-citation xml:lang="en">Karateev DE, Olyunin YuA, Luchikhina EL. New classification criteria for rheumatoid arthritis ACR/EULAR 2010 - a step forward to early diagnosis. Nauchno-prakticheskaya revmatologiya. 2011;49(1):10-5. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Mangana CM, Kargacin AB, Barraquer RI. Episcleritis as an ocular manifestation in a patient with COVID-19. Acta Ophthalmol. 2020 Dec;98(8):e1056-e1057. doi: 10.1111/aos.14484. Epub 2020 Jun 1.</mixed-citation><mixed-citation xml:lang="en">Mangana CM, Kargacin AB, Barraquer RI. Episcleritis as an ocular manifestation in a patient with COVID-19. Acta Ophthalmol. 2020 Dec;98(8):e1056-e1057. doi: 10.1111/aos.14484. Epub 2020 Jun 1.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Feizi S, Meshksar A, Naderi A, Esfandiari H. Anterior Scleritis Manifesting After Coronavirus Disease 2019: A Report of Two Cases. Cornea. 2021 Sep 1;40(9):1204-6. doi: 10.1097/ICO.0000000000002795.</mixed-citation><mixed-citation xml:lang="en">Feizi S, Meshksar A, Naderi A, Esfandiari H. Anterior Scleritis Manifesting After Coronavirus Disease 2019: A Report of Two Cases. Cornea. 2021 Sep 1;40(9):1204-6. doi: 10.1097/ICO.0000000000002795.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ceran BB, Ozates S. Ocular manifestations of coronavirus disease 2019. Graefes Arch Clin Exp Ophthalmol. 2020 Sep;258(9): 1959-63. doi: 10.1007/s00417-020-04777-7. Epub 2020 Jun 6.</mixed-citation><mixed-citation xml:lang="en">Ceran BB, Ozates S. Ocular manifestations of coronavirus disease 2019. Graefes Arch Clin Exp Ophthalmol. 2020 Sep;258(9): 1959-63. doi: 10.1007/s00417-020-04777-7. Epub 2020 Jun 6.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Market M, Angka L, Martel AB, et al. Flattening the COVID-19 curve with natural killer cell based immunotherapies. Front Immunol. 2020 Jun 23;11:1512. doi: 10.3389/fimmu.2020.01512. eCollection 2020.</mixed-citation><mixed-citation xml:lang="en">Market M, Angka L, Martel AB, et al. Flattening the COVID-19 curve with natural killer cell based immunotherapies. Front Immunol. 2020 Jun 23;11:1512. doi: 10.3389/fimmu.2020.01512. eCollection 2020.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Liao M, Liu Y, Yuan J, et al. Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19. Nat Med. 2020 Jun;26(6):842-4. doi: 10.1038/s41591-020-0901-9. Epub 2020 May 12.</mixed-citation><mixed-citation xml:lang="en">Liao M, Liu Y, Yuan J, et al. Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19. Nat Med. 2020 Jun;26(6):842-4. doi: 10.1038/s41591-020-0901-9. Epub 2020 May 12.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Wang C, Xie J, Zhao L, et al. Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients. EBioMedicine. 2020 Jul;57:102833. doi: 10.1016/j.ebiom.2020.102833. Epub 2020 Jun 20.</mixed-citation><mixed-citation xml:lang="en">Wang C, Xie J, Zhao L, et al. Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients. EBioMedicine. 2020 Jul;57:102833. doi: 10.1016/j.ebiom.2020.102833. Epub 2020 Jun 20.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Li J, Liu HH, Yin XD, et al. COVID-19 illness and autoimmune diseases: recent insights. Inflamm Res. 2021 Apr;70(4):407-28. doi: 10.1007/s00011-021-01446-1. Epub 2021 Feb 28.</mixed-citation><mixed-citation xml:lang="en">Li J, Liu HH, Yin XD, et al. COVID-19 illness and autoimmune diseases: recent insights. Inflamm Res. 2021 Apr;70(4):407-28. doi: 10.1007/s00011-021-01446-1. Epub 2021 Feb 28.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Cusick MF, Libbey JE, Fujinami RS. Molecular mimicry as a mechanism of autoimmune disease. Clin Rev Allergy Immunol. 2012 Feb;42(1):102-11. doi: 10.1007/s12016-011-8294-7.</mixed-citation><mixed-citation xml:lang="en">Cusick MF, Libbey JE, Fujinami RS. Molecular mimicry as a mechanism of autoimmune disease. Clin Rev Allergy Immunol. 2012 Feb;42(1):102-11. doi: 10.1007/s12016-011-8294-7.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Angileri F, Legare S, Marino A, et al. Molecular mimicry may explain multi-organ damage in COVID-19. Autoimmun Rev. 2020 Aug;19(8):102591. doi: 10.1016/j.autrev.2020.102591. Epub 2020 Jun 11.</mixed-citation><mixed-citation xml:lang="en">Angileri F, Legare S, Marino A, et al. Molecular mimicry may explain multi-organ damage in COVID-19. Autoimmun Rev. 2020 Aug;19(8):102591. doi: 10.1016/j.autrev.2020.102591. Epub 2020 Jun 11.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ. Коронавирусная болезнь 2019 (COVID-19) и аутоиммунитет. Научно-практическая ревматология. 2021;59(1):5-30.</mixed-citation><mixed-citation xml:lang="en">Nasonov EL. Coronavirus disease 2019 (COVID-19) and autoimmunity. Nauchno-prakticheskaya revmatologiya. 2021;59(1): 5-30. (In Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
