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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">mrj-1407</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Связь распространенности кардиометаболических заболеваний с наличием псориатического артрита у российских пациентов с псориазом</article-title><trans-title-group xml:lang="en"><trans-title>Relationship between the prevalence of cardiometabolic diseases and the presence of psoriatic arthritis in Russian patients with psoriasis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0662-2682</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богданова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogdanova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Витальевна Богданова</p><p>107076, Москва, ул. Короленко, 3, стр. 6</p></bio><bio xml:lang="en"><p>Elena Vitalievna Bogdanova</p><p>3, Korolenko Street, Build. 6, Moscow 107076</p></bio><email xlink:type="simple">onama@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7625-0503</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кубанов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kubanov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>107076, Москва, ул. Короленко, 3, стр. 6</p></bio><bio xml:lang="en"><p>3, Korolenko Street, Build. 6, Moscow 107076</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Scientific Center for Dermatovenereology and Cosmetology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>22</day><month>04</month><year>2023</year></pub-date><volume>17</volume><issue>2</issue><fpage>37</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Богданова Е.В., Кубанов А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Богданова Е.В., Кубанов А.А.</copyright-holder><copyright-holder xml:lang="en">Bogdanova E.V., Kubanov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1407">https://mrj.ima-press.net/mrj/article/view/1407</self-uri><abstract><p>Псориаз ассоциирован с повышенным риском кардиометаболической патологии. Сравнительных исследований ее распространенности у пациентов с псориазом в зависимости от наличия псориатического артрита (ПcА) на репрезентативной выборке российских пациентов не проводилось.</p><p>Цель исследования – сравнить распространенность кардиометаболических заболеваний у российских пациентов с псориазом в зависимости от наличия или отсутствия ПсА.</p><sec><title>Материал и методы</title><p>Материал и методы. Проанализированы данные регистра пациентов с псориазом Российского общества дерматовенерологов и косметологов (РОДВК). Критерии включения: возраст &gt;18 лет, наличие сведений об установленном диагнозе ПcА. Сопоставление проводили между пациентами с ПcА и двумя группами сравнения: всеми пациентами без ПcА и пациентами без ПcА с продолжительностью псориаза, превышающей установленное значение.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В анализ включено 920 пациентов с ПcА (группа 1) и 2325 больных псориазом без ПcА (группа 2). В группу 3 вошли 655 пациентов из группы 2.</p><p>Распространенность кардиометаболических заболеваний у пациентов с ПсА была выше, чем в группе 2. При сравнении с группой 3 статистическая значимость различий отмечалась только для нарушения толерантности к глюкозе. Однако с учетом поправки на пол и возраст пациенты с ПcА имели статистически значимо более высокие, чем в группе 3, шансы развития артериальной гипертензии (АГ), ишемической болезни сердца, стенокардии, острого нарушения мозгового кровообращения, нарушения толерантности к глюкозе и сахарного диабета 2-го типа. При введении поправок на факторы риска заболеваний статистическая значимость различий сохранялась для АГ и стенокардии.</p></sec><sec><title>Заключение</title><p>Заключение. Распространенность кардиометаболических заболеваний у российских пациентов с ПсА выше, чем у пациентов с псориазом без ПcА.</p></sec></abstract><trans-abstract xml:lang="en"><p>Psoriasis is associated with an increased risk of cardiometabolic pathology. Comparative studies of this pathology’s prevalence in patients with psoriasis depending on the presence of psoriatic arthritis (PsA) in a representative sample of Russian patients have not been conducted.</p><sec><title>Objective</title><p>Objective:to compare the prevalence of cardiometabolic diseases in Russian patients with psoriasis depending on the presence or absence of PsA.</p></sec><sec><title>Material and methods</title><p>Material and methods. The data of the register of patients with psoriasis of the Russian Society of dermatovenerologists and Cosmetologists (RODVK) were analyzed. Inclusion criteria: age &gt;18 years, information about the established diagnosis of PsA. A comparison was made between patients with PsA and two comparison groups: all patients without PsA and patients without PsA with a duration of psoriasis exceeding the established value.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The analysis included 920 patients with PsA (group 1) and 2325 patients with psoriasis without PsA (group 2). Group 3 included 655 patients from group 2.</p><p>The prevalence of cardiometabolic diseases in patients with PsA was higher than in group 2. When compared to group 3, the statistically significant differences were noted only for impaired glucose tolerance. However, adjusted for gender and age, patients with PsA had statistically significant higher chances of developing arterial hypertension (AH), coronary heart disease, angina pectoris, acute cerebrovascular accident, impaired glucose tolerance and diabetes mellitus than patients in group 3. When adjusting for disease risk factors, the statistical significance of differences remained for hypertension and angina pectoris.</p></sec><sec><title>Conclusion</title><p>Conclusion. The prevalence of cardiometabolic diseases in Russian patients with PsA is higher than in patients with psoriasis without PsA.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>псориатический артрит</kwd><kwd>коморбидность</kwd><kwd>распространенность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>psoriatic arthritis</kwd><kwd>comorbidity</kwd><kwd>prevalence</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Регистр пациентов с псориазом РОДВК является результатом работы многих людей. 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