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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2023-2-65-71</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1411</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Рупус – сочетание системной красной волчанки и ревматоидного артрита как отдельный фенотип болезни (описание клинического случая)</article-title><trans-title-group xml:lang="en"><trans-title>Rhupus – a combination of systemic lupus erythematosus and rheumatoid arthritis as a separate disease phenotype (a clinical case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4160-7218</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никишина</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikishina</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нина Юрьевна Никишина</p><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>Nina Yurievna Nikishina</p><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><email xlink:type="simple">lashinanina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1663-7810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aseeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5411-7317</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меснянкина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mesnyankina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5206-1732</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьев</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Soloviev</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>22</day><month>04</month><year>2023</year></pub-date><volume>17</volume><issue>2</issue><fpage>65</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никишина Н.Ю., Асеева Е.А., Меснянкина А.А., Соловьев С.К., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Никишина Н.Ю., Асеева Е.А., Меснянкина А.А., Соловьев С.К.</copyright-holder><copyright-holder xml:lang="en">Nikishina N.Y., Aseeva E.A., Mesnyankina A.A., Soloviev S.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1411">https://mrj.ima-press.net/mrj/article/view/1411</self-uri><abstract><p>Рупус (Rhupus) – редкое сочетание системной красной волчанки (СКВ) и ревматоидного артрита, одной из характерных особенностей которого является развитие эрозивного полиартрита на фоне основных иммунологических признаков СКВ. В статье представлено клиническое наблюдение, в котором у пациентки наряду с типичной иммунологической картиной СКВ выявлен эрозивный полиартрит с деформациями суставов кистей по типу «шеи лебедя», что потребовало назначение анти-Вклеточной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Rhupus is a rare combination of systemic lupus erythematosus (SLE) and rheumatoid arthritis, one of the characteristic features of which is the development of erosive polyarthritis on the background of the main immunological signs of SLE. The article presents a clinical observation in which, along with the typical immunological picture of SLE, the patient was diagnosed with erosive polyarthritis with “swan neck” type deformities of the hand joints, which required administration of anti-B-cell therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рупус</kwd><kwd>системная красная волчанка</kwd><kwd>ревматоидный артрит</kwd><kwd>ритуксимаб</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rhupus</kwd><kwd>systemic lupus erythematosus</kwd><kwd>rheumatoid arthritis</kwd><kwd>rituximab</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lockshin MD, Levine AB, Erkan D. Patients with overlap autoimmune disease differ from those with 'pure' disease. 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