mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2023-4-90-96mrj-1452Research ArticleОБЗОРЫREVIEWSМышечно-скелетные симптомы при системной красной колчанке с ювенильным дебютомMusculoskeletal symptoms in juvenile onset systemic lupus erythematosushttps://orcid.org/0000-0002-0513-6826КаледаМ. И.KaledaM. I.

Каледа Мария Игоревна.

115522, Москва, Каширское шоссе, 34А

Maria I. Kaleda.

34A, Kashirskoe Shosse, Moscow 115522

kaleda-mi@yandex.ruhttps://orcid.org/0000-0002-4156-5062АрефьеваА. Н.ArefievaA. N.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

https://orcid.org/0000-0003-1842-0348НикишинаИ. П.NikishinaI. P.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation2023200820231749096Copyright © Каледа М.И., Арефьева А.Н., Никишина И.П., 20232023Каледа М.И., Арефьева А.Н., Никишина И.П.Kaleda M.I., Arefieva A.N., Nikishina I.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1452

При ювенильном дебюте системной красной волчанки (СКВ) поражение опорно-двигательного аппарата является одним из наиболее частых проявлений. Мышечно-скелетные симптомы могут быть обусловлены активностью самого заболевания, повреждением, сформировавшимся вследствие активности СКВ, медикаментозным воздействием, а также сопутствующим заболеванием. Не являясь жизнеугрожающими, они, тем не менее, существенно влияют на тяжесть инвалидизации и социальной дезадаптации. В статье рассматривается клиническая характеристика различных причин мышечно-скелетных проявлений при СКВ с дебютом в детском и подростковом возрасте, грамотная интерпретация которых важна для диагностики и оценки активности СКВ, а также для коррекции терапии заболевания, что может способствовать улучшению отдаленного прогноза и качества жизни пациентов.

In juvenile onset systemic lupus erythematosus (SLE), musculoskeletal involvement is one of the most common manifestations. Musculoskeletal symptoms may be due to disease activity itself, organ damage due to SLE activity, drug exposure, or comorbidities. Although they are not life-threatening, they still have a significant impact on disability severity and social exclusion. This article discusses the clinical features of various causes of musculoskeletal manifestations in SLE with onset in childhood and adolescence, the adequate interpretation of which is important for diagnosing and evaluating SLE activity and for correcting the treatment of the disease, thereby improving the long-term prognosis and quality of life of patients.

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The authors declare that there are no conflicts of interest present.