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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2008-481</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-166</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Нестероидные противовоспалительные препараты в эпоху биологической терапии</article-title><trans-title-group xml:lang="en"><trans-title>Nonsteroidal anti-inflammatory drugs in the epoch of biological therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каратеев</surname><given-names>Андрей Евгеньевич</given-names></name><name name-style="western" xml:lang="en"><surname>Karateev</surname><given-names>A E</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Karateyev</surname><given-names>A E</given-names></name><name name-style="western" xml:lang="en"><surname>Karateyev</surname><given-names>A E</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2008</year></pub-date><volume>2</volume><issue>3</issue><issue-title>№3 (2008)</issue-title><fpage>3</fpage><lpage>6</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каратеев А.Е., Karateyev A.E., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Каратеев А.Е., Karateyev A.E.</copyright-holder><copyright-holder xml:lang="en">Karateev A.E., Karateyev A.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/166">https://mrj.ima-press.net/mrj/article/view/166</self-uri><abstract><p>Рассмотрены вред и польза применения нестероидных противовоспалительных препаратов (НПВП). Отмечено, что побочные эффекты НПВП - серьезная проблема, но они предсказуемы и предотвращаемы. Учет факторов риска, адекватное и своевременное лечение сопутствующих заболеваний и использование соответствующих профилактических мер позволяют свести к минимуму вероятность развития опасных осложнений. Сделан вывод, что польза от применения НПВП в целом превышает возможный вред их побочных эффектов.</p></abstract><trans-abstract xml:lang="en"><p>The risk and benefit of using nonsteroidal anti-inflammatory drugs (NSAIDs) are considered. The adverse reactions of NSAIDs are noted to be a serious problem, but they are predictable and preventable. Consideration of risk factors, adequate and timely treatment of comorbidity, and implementation of appropriate prophylactic measures minimize the likelihood of menacing complications. It is concluded that the benefit of the administration of NSAIDs generally overweighs the possible risk of their undesirable adverse effects.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
