mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2025-1-72-75mrj-1705Research ArticleДИАГНОСТИЧЕСКИЕ СТРАТЕГИИDIAGNOSTIC STRATEGIESАлгоритм мониторинга пациентов с аксиальным спондилоартритом в зависимости от активности заболеванияAlgorithm for monitoring patients with axial spondyloarthritis depending on the activity of the diseasehttps://orcid.org/0000-0003-3051-219XДацинаА. В.DatsinaA. V.

Анастасия Валерьевна Дацина,

115522, Москва, Каширское шоссе, 34А

Anastasia Valerievna Datsina,

34A, Kashirskoe Shosse, Moscow 115522

adasina@yandex.ruhttps://orcid.org/0000-0003-3195-5187ЭрдесШ. Ф.ErdesSh. F.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation2025150220251917275Copyright © Дацина А.В., Эрдес Ш.Ф., 20252025Дацина А.В., Эрдес Ш.Ф.Datsina A.V., Erdes S.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1705

При аксиальном спондилоартрите (аксСпА) проводится активная терапия генно-инженерными биологическими препаратами, но со временем ее эффективность снижается, что приводит к развитию обострения, появлению сильной и хронической боли, прогрессированию структурных изменений и ухудшению качества жизни, а также к значительным экономическим потерям. Международное сообщество все чаще обращает внимание на проблему выявления труднолечимых пациентов (difficult-to- treat, D2Т). В связи с этим возникла необходимость разработки стратегий и маркеров для их выявления и эффективного лечения. Авторы предлагают схему наблюдения, которая представляет собой инновационный подход к мониторингу пациентов с D2Т аксСпА.

Axial spondyloarthritis (axSpA) is actively treated with biologic disease-modifying antirheumatic drugs, but their efficacy decreases over time, leading to the development of exacerbation, the onset of severe and chronic pain, progression of structural changes and deterioration of quality of life, as well as significant economic losses. The international community is increasingly concerned about the problem of identifying difficultto-treat (D2T) patients. In this context, it is necessary to develop strategies and markers for their identification and effective treatment. The authors propose a regimen of follow-up that represents an innovative approach to monitoring patients with D2T axSpA.

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The authors declare that there are no conflicts of interest present.