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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2025-1-76-82</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1706</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Особенности системной красной волчанки у пациентов азиатского этноса</article-title><trans-title-group xml:lang="en"><trans-title>Characteristics of systemic lupus erythematosus in patients of Asian ethnicity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5433-3300</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Койлубаева</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Koilubaeva</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гулазык Маликовна Койлубаева,  </p><p>720040, Бишкек, ул. Тоголока Молдо, 3</p></bio><bio xml:lang="en"><p>Gulazyk Malikovna, Koilubaeva,</p><p>3, Togolok Moldo Street, Bishkek 720040</p></bio><email xlink:type="simple">makmal@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5206-1732</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aseeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1663-7810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьев</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Soloviev</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6068-3080</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А;</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522;</p><p>2/1, Barrikadnaya Street, Build. 1, Moscow 125993</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный центр кардиологии и терапии им. акад. Мирсаида Миррахимова при Министерстве здравоохранения Кыргызской республики</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>Academician M. Mirrakhimov National Center for Cardiology and Therapy</institution><country>Kyrgyzstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»;&#13;
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology;&#13;
Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>15</day><month>02</month><year>2025</year></pub-date><volume>19</volume><issue>1</issue><fpage>76</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Койлубаева Г.М., Асеева Е.А., Соловьев С.К., Лила А.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Койлубаева Г.М., Асеева Е.А., Соловьев С.К., Лила А.М.</copyright-holder><copyright-holder xml:lang="en">Koilubaeva G.M., Aseeva E.A., Soloviev S.K., Lila A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1706">https://mrj.ima-press.net/mrj/article/view/1706</self-uri><abstract><p>Системная красная волчанка (СКВ) характеризуется неблагоприятным исходом и непредсказуемым течением. Значительное влияние на течение и исход болезни оказывает принадлежность пациента к определенному этносу. СКВ у афроамериканцев и азиатов протекает в более тяжелой форме, чем у белых европейцев. В обзоре рассматриваются эпидемиологические данные, особенности течения и клинических проявлений СКВ у азиатов.</p></abstract><trans-abstract xml:lang="en"><p>Systemic lupus erythematosus (SLE) is characterized by an unpredictable and unfavorable course. The ethnicity of the patient has a significant impact on the course and outcome of the disease. SLE is more severe in African Americans and Asians than in white Europeans. This review examines epidemiological data, characteristics of the course and clinical manifestations of SLE in Asians.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>течение</kwd><kwd>клинические проявления</kwd><kwd>азиаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>course</kwd><kwd>clinical manifestations</kwd><kwd>Asians</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mahajan A, Herrmann M, Muсoz LE. Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE. Front Immunol. 2016 Feb 8; 7:35. doi: 10.3389/fimmu.2016.00035.</mixed-citation><mixed-citation xml:lang="en">Mahajan A, Herrmann M, Muсoz LE. Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE. 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