mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2008-488mrj-173Research ArticleСтатьиArticlesОсобенности артропатии при болезни УипплаThe specific features of arthropathy in Whipple's diseaseМаевИ. В.MaevI V-ЖиляевЕ. В.ZhilyaevE V-ДичеваД. Т.DichevaD T-БурагинаТ. А.BuraginaT A-ПрохороваЕ. Г.ProkhorovaE G-MayevI VMayevI V-ЖиляевЕ. В.ZhilyaevE V-ДичеваД. Т.DichevaD T-БурагинаТ. А.BuraginaT A-ПрохороваЕ. Г.ProkhorovaE G-20082509200823№3 (2008)4550Copyright © Маев И.В., Жиляев Е.В., Дичева Д.Т., Бурагина Т.А., Прохорова Е.Г., Mayev I.V., Жиляев Е.В., Дичева Д.Т., Бурагина Т.А., Прохорова Е.Г., 20082008Маев И.В., Жиляев Е.В., Дичева Д.Т., Бурагина Т.А., Прохорова Е.Г., Mayev I.V., Жиляев Е.В., Дичева Д.Т., Бурагина Т.А., Прохорова Е.Г.Maev I.V., Zhilyaev E.V., Dicheva D.T., Buragina T.A., Prokhorova E.G., Mayev I.V., Zhilyaev E.V., Dicheva D.T., Buragina T.A., Prokhorova E.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/173

Описано двухлетнее клиническое наблюдение мужчины 56 лет с болезнью Уиппла (БУ). Диагноз был установлен на основании обнаружения при компьютерной томографии расположенного за брюшиной и в брыжейке тонкой кишки инфильтрата низкой рентгеновской плотности и выявления в биоптате слизистой оболочки залуковичного отдела двенадцатиперстной кишки PAS-позитив-ных макрофагов. Артропатия развилась за 10 лет до появления кишечной симптоматики, стихла с ее развитием и возобновилась после достижения клинической ремиссии. На основании данного наблюдения и данных литературы обсуждаются взаимоотношения артропатии и абдоминальных проявлений БУ.

The authors describe a case of Whipple's disease (WD) in a 56-year-old male patient followed up for 2 years. The diagnosis was established on the evidence that there was a low-density retroperitoneal or mesenteric infiltrate at computed tomography and PAS-positive macrophages in the biopsy specimens of the duodenal retrobulbar mucosa. Arthropathy had developed within 10 years before the occurrence of intestinal symptoms, subsided with their progression, and recurred after their regression. On the basis of this observation and the data available in the literature, the authors discuss the relationships of arthropathy to the abdominal manifestations of WD.

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The authors declare that there are no conflicts of interest present.