mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2025-2-107-112mrj-1750Research ArticleОБЗОРЫREVIEWSСерьезные коморбидные инфекции у пациентов с воспалительными заболеваниями суставов: частота, структура, факторы рискаSevere comorbid infections in patients with inflammatory joint diseases: frequency, structure, risk factorshttps://orcid.org/0000-0002-5264-337XБарановаМ. М.BaranovaM. M.

Марина Михайловна Баранова

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»

115522, Москва, Каширское шоссе, 34А

Marina Mikhailovna Baranova

34A, Kashirskoe Shosse, Moscow, 115522

baranovamarina103@gmail.comhttps://orcid.org/0000-0003-4327-6720МуравьеваН. В.MuravyovaN. V.

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow, 115522

https://orcid.org/0000-0001-7091-2054БеловБ. С.BelovB. S.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow, 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation202522042025192107112Copyright © Баранова М.М., Муравьева Н.В., Белов Б.С., 20252025Баранова М.М., Муравьева Н.В., Белов Б.С.Baranova M.M., Muravyova N.V., Belov B.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1750

Серьезные коморбидные инфекции (СКИ) – инфекции, развивающиеся на фоне основного заболевания и требующие госпитализации и/или внутривенного введения антибактериальных препаратов. В структуре коморбидной инфекционной патологии у пациентов с воспалительными заболеваниями суставов (ВЗС) на долю СКИ приходится не более 4%. Однако именно они являются непосредственной причиной смерти этих пациентов. Развитию СКИ у пациентов с ВЗС способствуют различные факторы, в том числе социальнодемографические, а также связанные непосредственно с самим ВЗС, включая проводимую терапию.

В статье рассматриваются частота, структура, факторы риска СКИ у пациентов с ВЗС.

Severe comorbid infections (SCI) are infections that develop against the background of the underlying disease and require hospitalization and/or intravenous administration of antibacterial drugs. In the structure of comorbid infections in patients with inflammatory joint diseases (IJD), the number of SCI does not exceed 4%. However, they are the direct cause of death in these patients. Various factors, including sociodemographic factors, as well as factors directly related to the IJD itself, including therapy, contribute to the development of SCI. This article discusses the incidence, structure and risk factors in patients with IJD.

серьезные коморбидные инфекцииревматоидный артритспондилоартританкилозирующий спондилитпсориатический артритфакторы рискагенно-инженерные биологические препаратыsevere comorbid infectionsrheumatoid arthritisspondyloarthritisankylosing spondylitispsoriatic arthritisrisk factorsbiologic disease-modofying antirheumatic drugsИсследование выполнено в рамках научно-исследовательской работы, государственное задание №1021051503137-7The study was conducted as part of a research project, state assignment №1021051503137-7ReferencesGermano V, Cattaruzza MS, Osborn J, et al. Infection risk in rheumatoid arthritis and spondyloarthropathy patients under treatment with DMARDs, corticoster-oids and TNF- antagonists. J Transl Med. 2014 Mar 22:12:77. doi: 10.1186/1479-5876-12-77.Germano V, Cattaruzza MS, Osborn J, et al. Infection risk in rheumatoid arthritis and spondyloarthropathy patients under treatment with DMARDs, corticoster-oids and TNF- antagonists. 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The authors declare that there are no conflicts of interest present.