mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2025-4-7-12mrj-1802Research ArticleЛЕКЦИИLECTURESРевматологические маски ВИЧ-инфекции. Часть 1. Поражение опорно-двигательного аппаратаRheumatological mimickers of HIV infection. Part 1: involvement of the musculoskeletal systemhttps://orcid.org/0000-0002-0928-3911ГридневаГ. И.GridnevaG. I.

Галина Игоревна Гриднева,  

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

gigridneva@mail.ruhttps://orcid.org/0000-0001-7091-2054БеловБ. С.BelovB. S.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

https://orcid.org/0000-0001-8193-2325БухановаД. В.BukhanovaD. V.

119421, Москва, Ленинский просп., 111

111 Leninsky prospect, Moscow, 119421

https://orcid.org/0000-0002-1833-5357АроноваЕ. С.AronovaE. S.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian FederationАО «Р-ФАРМ»РоссияR-Pharm JSCRussian Federation202528082025194712Copyright © Гриднева Г.И., Белов Б.С., Буханова Д.В., Аронова Е.С., 20252025Гриднева Г.И., Белов Б.С., Буханова Д.В., Аронова Е.С.Gridneva G.I., Belov B.S., Bukhanova D.V., Aronova E.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1802

В первой части лекции обобщены современные данные, полученные при изучении когорт ВИЧ-инфицированных пациентов с клиническими признаками поражения структур опорно-двигательного аппарата и кожи. Ревматологические маски ВИЧ-инфекции разнообразны и, как показано в ряде работ, выполненных до и после широкого внедрения антиретровирусной терапии, встречаются с различной частотой, что может затруднить знакомство с данной проблемой, особенно для начинающего клинициста. По обобщенным данным литературы, наиболее часто на фоне ВИЧ-инфекции развиваются ревматоидный артрит, реактивный артрит, ВИЧ-ассоциированный атрит и артралгии, спондилоартрит, псориатический артрит. В настоящей статье уделено внимание обнаружению у таких больных остеопороза и остеонекроза. Рассмотрена классификация поражения мышц при ВИЧинфекции с акцентом на явления рабдомиолиза различного генеза.

This first part of the lecture summarizes current data obtained from studies of cohorts of HIV-infected patients presenting with clinical signs of musculoskeletal and skin involvement. The rheumatologic manifestations of HIV infection are diverse and, as shown in several studies conducted both before and after the widespread introduction of antiretroviral therapy, occur with varying frequency. This variability can complicate familiarity with the issue, particularly for early-career clinicians. According to the literature, the most observed conditions in the context of HIV infection include rheumatoid arthritis, reactive arthritis, HIV-associated arthritis and arthralgias, spondyloarthritis, and psoriatic arthritis. The present article also discusses the occurrence of osteoporosis and osteonecrosis in these patients. Furthermore, it reviews the classification of muscle involvement in HIV infection, with a focus on cases of rhabdomyolysis of various origins.

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The authors declare that there are no conflicts of interest present.