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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2025-4-81-85</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1813</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Варианты течения и индекс повреждения при системной красной волчанке</article-title><trans-title-group xml:lang="en"><trans-title>Clinical course and damage index in systemic lupus erythematosus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0634-5627</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шолкина</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sholkina</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полина Андреевна Шолкина,</p><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>Polina Andreevna Sholkina,</p><p>34A, Kashirskoye Shosse, Moscow 115522</p></bio><email xlink:type="simple">drpaulinasholkina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1318-1894</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шумилова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shumilova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoye Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3552-2522</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Решетняк</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Reshetnyak</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А; 125993, Москва, ул. Баррикадная, 2/1, стр. 1</p></bio><bio xml:lang="en"><p>34A, Kashirskoye Shosse, Moscow 115522;2/1, Barrikadnaya Street, Build. 1, Moscow 125993</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»;&#13;
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology;&#13;
Russian Medical Academy of Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2025</year></pub-date><volume>19</volume><issue>4</issue><fpage>81</fpage><lpage>85</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шолкина П.А., Шумилова А.А., Решетняк Т.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шолкина П.А., Шумилова А.А., Решетняк Т.М.</copyright-holder><copyright-holder xml:lang="en">Sholkina P.A., Shumilova A.A., Reshetnyak T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1813">https://mrj.ima-press.net/mrj/article/view/1813</self-uri><abstract><p>В обзоре рассматриваются варианты течения системной красной волчанки (СКВ). Обсуждаются сложность прогнозирования обострений и неоднородность течения СКВ. Особое внимание уделено индексу повреждения, который коррелирует с долгосрочным прогнозом и качеством жизни пациентов.</p></abstract><trans-abstract xml:lang="en"><p>This review examines the various types of systemic lupus erythematosus (SLE) course. It discusses the challenges in predicting disease flares and the heterogeneity of SLE progression. Special attention is given to the damage index, which correlates with long-term outcomes and patients’ quality of life.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>модели активности системной красной волчанки</kwd><kwd>индекс повреждения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>systemic lupus erythematosus activity patterns</kwd><kwd>damage index</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонова ВА. Системная красная волчанка. Москва; 1972.</mixed-citation><mixed-citation xml:lang="en">Nasonova VA. Systemic Lupus Erythematosus. Moscow; 1972.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Решетняк ТМ. Системная красная волчанка. В кн.: Бадокин ВВ, редактор. Ревматология. Клинические лекции. 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