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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2026-2-108-114</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1965</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Артериит Такаясу у детей и взрослых: эпидемиологические данные, клинические проявления, выживаемость и смертность</article-title><trans-title-group xml:lang="en"><trans-title>Takayasu arteritis in children and adults: epidemiological data, clinical manifestations, survival, and mortality</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1880-5678</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болотбекова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bolotbekova</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алтынай Маратовна Болотбекова </p><p>720040, Бишкек, ул. Тоголока Молдо, 3 </p></bio><bio xml:lang="en"><p>Altynai Maratovna Bolotbekova </p><p>3, Togolok Moldo Street, Bishkek 720040 </p></bio><email xlink:type="simple">altynajbolotbekova981@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5433-3300</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Койлубаева</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Koilubaeva</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>720040, Бишкек, ул. Тоголока Молдо, 3 </p></bio><bio xml:lang="en"><p>3, Togolok Moldo Street, Bishkek 720040 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4846-5531</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>15522, Москва, Каширское шоссе, 34А </p><p>129110, Москва, ул. Щепкина, 61/2 </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p><p>61/2, Shchepkina Street, Moscow 129110, Moscow </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4906-7148</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Guseva</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>15522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2431-2039</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Окунова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Okunova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>720040, Бишкек, ул. Тоголока Молдо, 3 </p></bio><bio xml:lang="en"><p>3, Togolok Moldo Street, Bishkek 720040 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9933-5350</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>15522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-1444-5376</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдыкеримов</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdykerimov</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>720040, Бишкек, ул. Тоголока Молдо, 3 </p></bio><bio xml:lang="en"><p>3, Togolok Moldo Street, Bishkek 720040 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-4064-2980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ашуралиев</surname><given-names>Ш. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Ashuraliev</surname><given-names>Sh. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>720040, Бишкек, ул. Тоголока Молдо, 3 </p></bio><bio xml:lang="en"><p>3, Togolok Moldo Street, Bishkek 720040 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный центр кардиологии и терапии им. акад. Мирсаида Миррахимова при Министерстве здравоохранения Кыргызской Республики</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>National Center of Cardiology and Therapy named after Academician Mirsaid Mirrakhimov under the Ministry of Health of the Kyrgyz Republic</institution><country>Kyrgyzstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой» ; ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology ; M.F. Vladimirsky Moscow Regional Research Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>22</day><month>04</month><year>2026</year></pub-date><volume>20</volume><issue>2</issue><fpage>108</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Болотбекова А.М., Койлубаева Г.М., Егорова О.Н., Гусева И.А., Окунова А.А., Тарасова Г.М., Абдыкеримов А.О., Ашуралиев Ш.П., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Болотбекова А.М., Койлубаева Г.М., Егорова О.Н., Гусева И.А., Окунова А.А., Тарасова Г.М., Абдыкеримов А.О., Ашуралиев Ш.П.</copyright-holder><copyright-holder xml:lang="en">Bolotbekova A.M., Koilubaeva G.M., Egorova O.N., Guseva I.A., Okunova A.A., Tarasova G.M., Abdykerimov A.O., Ashuraliev S.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1965">https://mrj.ima-press.net/mrj/article/view/1965</self-uri><abstract><p>Распространенность артериита Такаясу (АТ), клиническая картина и показатели выживаемости могут различаться у пациентов в зависимости от возраста дебюта заболевания и региона проживания. Генез такого несоответствия не выявлен, патогенетические механизмы связывают с генетическими, аутоиммунными и инфекционными факторами. Неспецифичность и многообразие симптомов приводят к запоздалой диагностике и развитию ишемических осложнений. В статье представлен обзор публикаций, посвященных особенностям течения АТ в разных возрастных и этнических группах.</p></abstract><trans-abstract xml:lang="en"><p>The prevalence of Takayasu arteritis (TA), its clinical presentation, and survival rates may vary among patients depending on age at disease onset and region of residence. The origin of this heterogeneity has not been fully elucidated; pathogenetic mechanisms are associated with genetic, autoimmune, and infectious factors. Nonspecific and heterogeneous symptoms lead to delayed diagnosis and the development of ischemic complications. This article presents a review of publications addressing the characteristics of TA across different age and ethnic groups.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериит Такаясу</kwd><kwd>активность</kwd><kwd>исход</kwd><kwd>когорта</kwd><kwd>выживаемость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Takayasu arteritis</kwd><kwd>disease activity</kwd><kwd>outcome</kwd><kwd>cohort</kwd><kwd>survival</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена в рамках научно-исследовательской работы (№/№ государственных заданий РК 125020501434-1) и международного сотрудничества ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой» (Россия) и Национального центра кардиологии и терапии им. акад. Мирсаида Миррахимова при Министерстве здравоохранения Кыргызской республики (Кыргызстан).</funding-statement><funding-statement xml:lang="en">The article was prepared as a part of the research work (№/№ of government tasks РК 125020501434-1) and international cooperation of V.A. Nasonova Research Institute of Rheumatology (Russia) and the National Center of Cardiology and Therapy named after Academician Mirsaid Mirrakhimov at the Ministry of Health of the Kyrgyz Republic (Kyrgyz Republic).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wahren-Herlenius M, Dorner T. Immunopathogenetic mechanisms of systemic autoimmune diseases. Lancet. 2013 Aug 31; 382(9894):819-31. doi: 10.1016/S0140-6736(13)60954-X.</mixed-citation><mixed-citation xml:lang="en">Wahren-Herlenius M, Dorner T. Immunopathogenetic mechanisms of systemic autoimmune diseases. 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