mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2026-3-7-11mrj-1991Research ArticleЛЕКЦИЯLECTUREЛабораторные биомаркеры поражения сердца при системной склеродермии. Часть 2Laboratory biomarkers of cardiac involvement in systemic sclerosis. Part 2https://orcid.org/0000-0002-5012-0540ГарзановаЛ. А.GarzanovaL. A.

Людмила Александровна Гарзанова

Москва, 115522, Москва, Каширское шоссе, 34А 

Lyudmila Aleksandrovna Garzanova

34A, Kashirskoe Shosse, Moscow 115522 

lyuda-garzanova@yandex.ruhttps://orcid.org/0000-0002-3248-6426АнаньеваЛ. П.AnanyevaL. P.

Москва, 115522, Москва, Каширское шоссе, 34А 

34A, Kashirskoe Shosse, Moscow 115522 

https://orcid.org/0000-0003-3650-7658КоневаО. А.KonevaO. A.

Москва, 115522, Москва, Каширское шоссе, 34А 

34A, Kashirskoe Shosse, Moscow 115522 

https://orcid.org/0000-0003-2667-4284ОвсянниковаО. Б.OvsyannikovaO. B.

Москва, 115522, Москва, Каширское шоссе, 34А 

34A, Kashirskoe Shosse, Moscow 115522 

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation202624062026203711Copyright © Гарзанова Л.А., Ананьева Л.П., Конева О.А., Овсянникова О.Б., 20262026Гарзанова Л.А., Ананьева Л.П., Конева О.А., Овсянникова О.Б.Garzanova L.A., Ananyeva L.P., Koneva O.A., Ovsyannikova O.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/1991

Системная склеродермия (ССД) характеризуется мультисистемностью поражения и представляет собой серьезную клиническую проблему для врачей и пациентов. Среди висцеральных проявлений ССД первичное поражение сердца является одним из самых тяжелых и часто поздно диагностируемых. Определение биомаркеров может внести большой вклад в раннюю диагностику кардиопатии при ССД.

Вторая часть статьи посвящена возможностям использования различных цитокинов и других молекул для диагностики и определения прогноза при первичном поражении сердца, ассоциированном с ССД. 

Systemic sclerosis (SSc) is characterized by multisystem involvement and represents a serious clinical challenge for physicians and patients. Among the visceral manifestations of SSc, primary cardiac involvement is one of the most severe and is often diagnosed late. Biomarker assessment can make a major contribution to the early diagnosis of cardiopathy in SSc.

The second part of the article is devoted to the potential use of various cytokines and other molecules for diagnosis and prognostic assessment of primary cardiac involvement associated with SSc. 

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The authors declare that there are no conflicts of interest present.