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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2026-3-67-71</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-1999</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>История и современные тенденции экстракорпоральных методов терапии в ревматологии. Часть 1. Лечение системной красной волчанки</article-title><trans-title-group xml:lang="en"><trans-title>History and current trends in extracorporeal methods of therapy in rheumatology. Part 1. Treatment of systemic lupus erythematosus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-1269-5799</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плетнёв</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pletnev</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Андреевич Плетнёв</p><p>115522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p></bio><email xlink:type="simple">eugenepletnev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1663-7810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aseeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5206-1732</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьев</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Solovyev</surname><given-names>S. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5105-0313</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Покровский</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pokrovsky</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>121552, Москва, ул. Академика Чазова, 15А </p></bio><bio xml:lang="en"><p>15A, Academician Chazov Street, Moscow 121552 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-8106-8091</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдуллин</surname><given-names>Е. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdullin</surname><given-names>E. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>119991, Москва, Лениские горы, 1</p></bio><bio xml:lang="en"><p>1, Leninskie Gory, Moscow 119991 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-9646-6763</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аверкиев</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Averkiev</surname><given-names>V. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>123056, Москва, Грузинский переулок, 3А </p></bio><bio xml:lang="en"><p>3A, Gruzinsky Lane, Moscow 123056 </p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4579-2836</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зоткин</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zotkin</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6068-3080</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А </p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1 </p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522 </p><p>2/1, Barrikadnaya Street, Build. 1, Moscow 125993 </p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр кардиологии им. акад. Е.И. Чазова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Cardiology named after Academician E.I. Chazov, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГОУ ВО «Московский государственный университет им. М.В. Ломоносова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>АО Группа компаний «Медси»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>AO GK MEDSI</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>24</day><month>06</month><year>2026</year></pub-date><volume>20</volume><issue>3</issue><fpage>67</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Плетнёв Е.А., Асеева Е.А., Соловьев С.К., Покровский Н.С., Абдуллин Е.Т., Аверкиев В.Л., Зоткин Е.Г., Лила А.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Плетнёв Е.А., Асеева Е.А., Соловьев С.К., Покровский Н.С., Абдуллин Е.Т., Аверкиев В.Л., Зоткин Е.Г., Лила А.М.</copyright-holder><copyright-holder xml:lang="en">Pletnev E.A., Aseeva E.A., Solovyev S.K., Pokrovsky N.S., Abdullin E.T., Averkiev V.L., Zotkin E.G., Lila A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/1999">https://mrj.ima-press.net/mrj/article/view/1999</self-uri><abstract><p>Патогенез аутоиммунных ревматических заболеваний – сложный многофакторный процесс, в основе которого лежит активация различных звеньев иммунной системы. Одним из подходов к лечению данных заболеваний являются технологии экстракорпоральной терапии, которые представляют собой методики, направленные на удаление из крови компонентов, участвующих в патогенезе заболеваний и приводящих к повреждению тканей. В обзоре рассматриваются различные методики терапевтического афереза, которые применяются для лечения системной красной волчанки. </p></abstract><trans-abstract xml:lang="en"><p>The pathogenesis of autoimmune rheumatic diseases is a complex multifactorial process based on activation of various components of the immune system. One of the approaches to the treatment of these diseases is extracorporeal therapy technologies, which are techniques aimed at removing from the blood the components involved in pathogenesis and leading to tissue damage. This review discusses various therapeutic apheresis techniques used for the treatment of systemic lupus erythematosus. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>экстракорпоральная терапия</kwd><kwd>терапевтический аферез</kwd><kwd>плазмаферез</kwd><kwd>плазмосорбция</kwd><kwd>цитаферез</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>extracorporeal therapy</kwd><kwd>therapeutic apheresis</kwd><kwd>plasmapheresis</kwd><kwd>plasmosorption</kwd><kwd>cytapheresis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ Современная концепция аутоиммунитета в ревматологии. Научнопрактическая ревматология. 2023;61(4): 397-420.</mixed-citation><mixed-citation xml:lang="en">Nasonov EL Modern concept of autoimmunity in rheumatology. Nauchno-prakticheskaya revmatologiya. 2023;61(4):397-420. 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