References

mrj

Современная ревматология

Modern Rheumatology Journal

1996-70122310-158X

IMA-PRESS, LLC

10.14412/1996-7012-2026-2-72-77

mrj-2000

Research Article

ОБЗОРЫ

REVIEWS

Поражение желудочно-кишечного тракта при системной склеродермии

Gastrointestinal tract involvement in systemic sclerosis

https://orcid.org/0000-0002-9134-9624

Алекперов

Р. Т.

Alekperov

R. T.

Ризван Таир оглы Алекперов

129110, Москва, ул. Щепкина, 61/2

Rizvan Tair ogly Alekperov

61/2, Shchepkina Street, Moscow 129110

ralekperov@list.ru

ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»РоссияM.F. Vladimirsky Moscow Regional Research Clinical InstituteRussian Federation

2026

24062026

2037278

2026

Алекперов Р.Т.

Alekperov R.T.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://mrj.ima-press.net/mrj/article/view/2000

Системная склеродермия (ССД) – хроническое аутоиммунное заболевание, которое характеризуется генерализованной микроангиопатией, фиброзом кожи и внутренних органов. Желудочно-кишечный тракт (ЖКТ) является наиболее часто поражаемой системой органов при ССД, а признаки вовлечения ЖКТ нередко возникают на ранних стадиях заболевания. В настоящее время одобренные варианты лечения поражений ЖКТ при ССД ограничены, при этом подходы к лечению патологии разных отделов ЖКТ имеют принципиальные различия. Несмотря на высокую распространенность, гастроэнтерологические осложнения ССД недостаточно освещены в литературе. В обзоре проанализированы современные методы диагностики и лечения поражений ЖКТ при ССД

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by generalized microangiopathy and fibrosis of the skin and internal organs. The gastrointestinal (GI) tract is the most frequently affected organ system in SSc, and signs of GI involvement often occur at early stages of the disease. Currently, approved treatment options for GI involvement in SSc are limited, while approaches to treatment of different GI segments’ differ fundamentally. Despite its high prevalence, gastroenterological complications of SSc are insufficiently covered in the literature. This review analyzes current methods for the diagnosis and treatment of GI involvement in SSc.

системная склеродермияэзофагитгастропарезпсевдообструкция кишечникасиндром избыточного бактериального ростанедержание кала

systemic sclerosisesophagitisgastroparesisintestinal pseudo-obstructionsmall intestinal bacterial overgrowth syndromefecal incontinence

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The authors declare that there are no conflicts of interest present.