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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2009-567</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-252</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Проблема инвазивных микозов в ревматологии (часть I)</article-title><trans-title-group xml:lang="en"><trans-title>THE PROBLEM OF INVASIVE MYCOSES IN RHEUMATOLOGY(Part I)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belov</surname><given-names>Boris Sergeyevich</given-names></name></name-alternatives><email xlink:type="simple">belovbor@yandex.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>O N</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>G M</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полянская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyanskaya</surname><given-names>M V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балабанова</surname><given-names>Римма Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Balabanova</surname><given-names>R M</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>13</day><month>12</month><year>2009</year></pub-date><volume>3</volume><issue>4</issue><issue-title>№4 (2009)</issue-title><fpage>11</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белов Б.С., Егорова О.Н., Тарасова Г.М., Полянская М.В., Балабанова Р.М., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Белов Б.С., Егорова О.Н., Тарасова Г.М., Полянская М.В., Балабанова Р.М.</copyright-holder><copyright-holder xml:lang="en">Belov B.S., Egorova O.N., Tarasova G.M., Polyanskaya M.V., Balabanova R.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/252">https://mrj.ima-press.net/mrj/article/view/252</self-uri><abstract><p>В современной ревматологии проблема инвазивных микозов приобретает все большую актуальность. Отмечаются слабая настороженность врачей в отношении микозов у больных системными ревматическими заболеваниями, сложность прижизненной диагностики, трудности терапии. Значение данной проблемы существенно повышается в связи с активным внедрением в клиническую практику биологических агентов, в первую очередь ингибиторов фактора некроза опухоли а (инфликсимаб, адалимумаб, этанерцепт), что сопровождается нарастанием риска развития оппортунистических инфекций. В первой части обзора представлена информация о различных аспектах системного аспергиллеза, включая тактику его диагностики и рациональной терапии.</p></abstract><trans-abstract xml:lang="en"><p>The problem of invasive mycoses is becoming ever more urgent in modern rheumatology. The fact that physicians are unalert to mycoses in patients with systemic rheumatic diseases and that there are difficulties in their lifetime diagnosis and treatment is noteworthy. The significance of this problem substantially increases with the active clinical introduction of biologicals, primarily tumor necrosis factor а inhibitors (infliximab, adalimumab, etanercept), which goes on concurrently with the increasing risk for opportunistic infections. Part I presents information on different aspects of systemic aspergillosis, including the tactics of its diagnosis and rational therapy</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматические заболевания</kwd><kwd>аспергиллез</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatic diseases</kwd><kwd>aspergillosis</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
