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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2009-575</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-260</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Остеопороз при системной красной волчанке</article-title><trans-title-group xml:lang="en"><trans-title>OSTEOPOROSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Середавкина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Seredavkina</surname><given-names>N V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Решетняк</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Reshetnyak</surname><given-names>Tatyana Magomedaliyevna</given-names></name></name-alternatives><email xlink:type="simple">t_reshetnyak@yahoo.com</email></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>13</day><month>12</month><year>2009</year></pub-date><volume>3</volume><issue>4</issue><issue-title>№4 (2009)</issue-title><fpage>59</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Середавкина Н.В., Решетняк Т.М., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Середавкина Н.В., Решетняк Т.М.</copyright-holder><copyright-holder xml:lang="en">Seredavkina N.V., Reshetnyak T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/260">https://mrj.ima-press.net/mrj/article/view/260</self-uri><abstract><p>Пациенты с системной красной волчанкой (СКВ) входят в группу высокого риска в отношении развития остеопороза (ОП) из-за наличия аутоиммунного воспаления, сопутствующей патологии и их лечения. Показано, что при возникновении ОП при СКВ потеря костной массы начинается рано и ассоциируется с назначением глюкокортикоидов (ГК). С целью профилактики ОП всем больным СКВ необходимо модифицировать образ жизни. Пациентам с факторами риска ОП и/или находящимся в постменопаузе для верификации изменений в костях проводят денситометрию. Для профилактики ОП применяют препараты кальция и витамин D, с целью терапии ОП - бисфосфонаты, которые достоверно снижают риск переломов позвоночника и шейки бедра у больных СКВ. Приведено описание больной СКВ с глюкокортикоид-индуцированным ОП и хорошим эффектом лечения бисфофонатами</p></abstract><trans-abstract xml:lang="en"><p>Patients with systemic lupus erythematosus (SLE) form a high risk group osteoporosis (OP). Its main causes are autoimmune inflammation, concomitant pathology, and their treatment. When OP occurs in SLE, bone mass loss is shown to occur early and is associated with the use of glucocorticosteroids (GC). To prevent OP, all patients with SLE should modify their lifestyle. To verify bone changes, densitometry is performed in patients who have risk factors of OP and/or a menopause. Calcium preparations and vitamin D are used to prevent OP; bisphosphonates that significantly reduce the risk of fractures of the vertebral column and femoral neck are employed for therapy of OP. A SLE patient with gluco-corticoid-induced OP and a good effect of bisphophonate treatment is described.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>остеопороз</kwd><kwd>бисфосфонаты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>osteoporosis</kwd><kwd>bisphosphonates</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
