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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2010-586</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-271</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Мелоксикам: перспективы примененияпри узловатой эритеме</article-title><trans-title-group xml:lang="en"><trans-title>MELOXICAM: USE PROSPECTS IN ERYTHEMA NODOSUM</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>O N</given-names></name></name-alternatives><email xlink:type="simple">onegorova@yandex.ru &amp;lt;mailto:onegorova@yandex.ru&amp;gt;</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belov</surname><given-names>B S</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балабанова</surname><given-names>Римма Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Balabanova</surname><given-names>R M</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpova</surname><given-names>Yu A</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>O N</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belov</surname><given-names>B S</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балабанова</surname><given-names>Римма Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Balabanova</surname><given-names>R M</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpova</surname><given-names>Yu A</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>14</day><month>03</month><year>2010</year></pub-date><volume>4</volume><issue>1</issue><issue-title>№1 (2010)</issue-title><fpage>41</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Егорова О.Н., Белов Б.С., Балабанова Р.М., Карпова Ю.А., Егорова О.Н., Белов Б.С., Балабанова Р.М., Карпова Ю.А., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Егорова О.Н., Белов Б.С., Балабанова Р.М., Карпова Ю.А., Егорова О.Н., Белов Б.С., Балабанова Р.М., Карпова Ю.А.</copyright-holder><copyright-holder xml:lang="en">Egorova O.N., Belov B.S., Balabanova R.M., Karpova Y.A., Egorova O.N., Belov B.S., Balabanova R.M., Karpova Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/271">https://mrj.ima-press.net/mrj/article/view/271</self-uri><abstract><p>Нестероидные противовоспалительные препараты широко используются в комплексной терапии болевого синдрома. Представлены патофизиологические механизмы развития острой и хронической боли. Подробно описаны функции циклооксигеназы (ЦОГ) 1-го
и 2-го типа, показана ключевая роль ЦОГ 2 в индукции и трансмиссии боли. Ступенчатый курс терапии мелоксикамом позволяет
в короткие сроки купировать болевой синдром. Представленное клиническое наблюдение демонстрирует выраженный анальгетический и противовоспалительный эффект мелоксикама (Мовалиса) у пациентки с узловатой эритемой.</p></abstract><trans-abstract xml:lang="en"><p>Nonsteroidal anti-inflammatory drugs are widely used in rheumatology in the complex therapy of pain syndrome. The paper describes the pathophysiological
mechanisms of development of acute and chronic pain. The action of cyclooxygenases (COX) (types 1 and 2) is detailed. The key role
of COX-2 in the induction and transmission is shown. The stepwise course of meloxicam relieves pain syndrome in the shortest possible time. The
presented case demonstrates the analgesic and anti-inflammatory effects of meloxicam (Movalis) in a female patient with erythema nodosum.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мелоксикам</kwd><kwd>узловатая эритема</kwd></kwd-group><kwd-group xml:lang="en"><kwd>meloxicam</kwd><kwd>erythema nodosum</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
