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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2011-669</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-354</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Неспецифическая боль в пояснично-крестцовой области: клинические особенностии подходы к медикаментозной терапии (по материалам европейских рекомендацийпо лечению неспецифической боли в пояснично-крестцовой области)</article-title><trans-title-group xml:lang="en"><trans-title>Nonspecific pain in the lumbosacral area: clinical features of and approachesto drug therapy (according to the materials of the European guidelinesfor the management of nonspecific lumbosacral pain)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раскина</surname><given-names>Татьяна Алексеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Raskina</surname><given-names>Tat'yana Alekseevna</given-names></name></name-alternatives><email xlink:type="simple">rassib@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Koroleva</surname><given-names>M V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раскина</surname><given-names>Татьяна Алексеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Raskina</surname><given-names>Tatyana Alekseyevna</given-names></name></name-alternatives><email xlink:type="simple">rassib@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Королева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Koroleva</surname><given-names>M V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>14</day><month>06</month><year>2011</year></pub-date><volume>5</volume><issue>2</issue><issue-title>№2 (2011)</issue-title><fpage>50</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Раскина Т.А., Королева М.В., Раскина Т.А., Королева М.В., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Раскина Т.А., Королева М.В., Раскина Т.А., Королева М.В.</copyright-holder><copyright-holder xml:lang="en">Raskina T.A., Koroleva M.V., Raskina T.A., Koroleva M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/354">https://mrj.ima-press.net/mrj/article/view/354</self-uri><abstract><p>Представлены особенности клинической картины, диагностики и лечения болевого синдрома в пояснично-крестцовой области.</p></abstract><trans-abstract xml:lang="en"><p>The paper describes the .specific features of the clinical presentation, diagnosis, and treatment of pain syndrome in the lumbosacral area.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль в пояснично-крестцовой области</kwd><kwd>анальгетическая терапия</kwd><kwd>сирдалуд</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lumbosacral pain</kwd><kwd>analgesic therapy</kwd><kwd>sirdalud</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Airaksinen O., Brox J.I., Cedraschi C. et al. European guidelines for the management of chronic nonspecific low back pain. Eur Spine J 2006; 15(2): 192-300.&lt;/p&gt;&lt;p&gt;Andersson G.B.J. The epidemiology of spinal disorders. In: Frymoyer J.W., ed. The adult spine: principles and practice. 2nd ed. New York: Raven Press, 1997; 93-141.&lt;/p&gt;&lt;p&gt;Frymoyer J.W. Back pain and sciatica. N Engl J Med 1988; 318: 291-300.&lt;/p&gt;&lt;p&gt;Royal College of General Practitioners. Clinical Guidelines for the Management of Acute Low Back Pain. London: Royal College of General Practitioners, 1996 and 1999.&lt;/p&gt;&lt;p&gt;Hoogendoorn W.E., van Poppel M.N.M., Bongers P.M. et al. Systemic review of psychosocial factors at work and private life as risk factors for back pain. Spine 2000; 25: 2114-25.&lt;/p&gt;&lt;p&gt;Linton S.J. A review of psychological risk factors in back and neck pain. Spine 2000; 25: 1148-56.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Assendelft W.J.J., Koes B.W. et al. Spinal radiographic findings and nonspecific low back pain: a systematic review of observational studies. Spine 1997; 22: 427-34.&lt;/p&gt;&lt;p&gt;Jarvik J.G., Hollingworth W., Martin B. et al. Rapid magnetic resonance imaging vs radiographs for patients with low back pain: a randomized controlled trial. JAMA 2003; 289: 2810-8.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Koes B.W., Bouter L.M. Conservative treatment of acute and chronic nonspecific low back pain: a systematic review of randomized controlled trials of the most common interventions. Spine 1997; 22: 2128-56.&lt;/p&gt;&lt;p&gt;De Craen A.J.M., Di Giulio G., Lampe- Schoenmaeckers A.J.E.M. et al. Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: a systematic review. Br Med J 1996; 313: 321-5.&lt;/p&gt;&lt;p&gt;Koes B.W., Scholten R.J.P.M., Mens J.M.A. et al. Efficacy of non-steroidal anti-inflammatory drugs for low back pain: a systematic review of randomised clinical trials. Ann Rheum Dis 1997; 56: 214-23.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Scholten R.J.P.M., Koes B.W. et al. Non-steroidal anti-inflammatory drugs (NSAIDs) for non-specific low back pain (Cochrane Review). In: The Cochrane Library, Issue 4, Oxford: Update Software 2000.&lt;/p&gt;&lt;p&gt;Henry D., Lim L.L.Y., Rodriguez L.A.G. et al. Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis. Br Med J 1996; 312: 1563-6.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Touray T., Furlan A.D. et al. Muscle relaxants for non-specific low back pain (Cochrane Review). In: The Cochrane Library, Issue 1. Chichester, UK: John Wiley &amp;amp; Sons, Ltd, 2004.15.&lt;/p&gt;&lt;p&gt;Bigos S., Bowyer O., Braen G. et al. Acute low back problems in adults. Clinical practice guideline no. 14. AHCPR publication no. 95-0642. Rockville, MD: Agency for Health Care Policy and Research, Public Health Service, U.S. Department of health and Human Services. December 1994.&lt;/p&gt;&lt;p&gt;Van Tulder M., Becker A., Bekkering T. et al. European guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J 2006; 15(Suppl. 2): 169-91.&lt;/p&gt;&lt;p&gt;Данилов А.Б. Возможности применения тизанидина (сирдалуда) в клинической практике. Обзор литературы. РМЖ 2009; 17 (20): 1370.&lt;/p&gt;&lt;p&gt;Coward D.M. Tizanidine: Neuropharmacology and mechanism of action. Neurology 1994; 44(Suppl. 9): 6-11.&lt;/p&gt;&lt;p&gt;Hutchinson D.R., Daniels F. A multinational study in general practice to evaluate the effectiveness and tolerability of tizanidine in the treatment of painful muscle spasms. Br J Clin Res 1990; 1: 39-48.&lt;/p&gt;&lt;p&gt;Berry H., Hutchinson D.R. Tizanidine and ibuprofen in acute low-back pain: Results of a double-blind multicentre study in general practice. J Intern Med Res 1988; 16: 83-91.&lt;/p&gt;&lt;p&gt;Sirdalud Ternilin Asia-Pacific Study group. Efficacy and gastroprotective effects of tizanidine plus diclofenac versus placebo plus diclofenac in patients with painful muscle spasm. Curr Ther Res 1998; 59: 13-22.&lt;/p&gt;&lt;p&gt;Бадокин В.В. Применение сирдалуда в ревматологической практике. РМЖ 2005; 13(24): 1588-9.&lt;/p&gt;&lt;p&gt;Bettucci D., Testa L., Calzoni S. et al. Combination of tizanidine and amitriptyline in the prophylaxis of chronic tension - type headache: evaluation of efficacy and impact on quality of life. J Headache Pain 2006; 7(1): 34-6.&lt;/p&gt;&lt;p&gt;Воробьева О.В. Возможности альфа2- адренергических агонистов в лечении миофасциальной боли. РМЖ 2007; 5: 445-8.&lt;/p&gt;&lt;p&gt;McCleane G.J. Does Gabapentin have an analgesic effect on background, movement and referred pain? A randomised, doubleblind, placebo controlled study. Pain Clinic 2001; 13: 103-7.&lt;/p&gt;&lt;p&gt;Keitel W., Frerick H., Kuhn U. et al. Capsicum pain plaster in chronic non-specific low back pain. Arzneimittelforschung 2001; 51(11): 896-903.&lt;/p&gt;&lt;p&gt;Frerick H., Keitel W., Kuhn U. et al. Topical treatment of chronic low back pain with a capsicum plaster. Pain 2003; 106(1- 2): 59-64.&lt;/p&gt;&lt;p&gt;Koes B.W., Scholten R.J.P.M., Mens J.M.A. et al. Epidural steroid injections for low back pain and sciatica: an updated systematic review of randomized clinical trials. Pain Digest 1999; 9: 241-7.&lt;/p&gt;&lt;p&gt;Nelemans P.J., de Bie R.A., de Vet H.C.W. et al. Injection therapy for subacute and chronic benign low back pain. In: The Cochrane Library, Issue 4. Oxford: Update Software, 2001.&lt;/p&gt;&lt;p&gt;Watts R.W., Silagy C.A. A meta-analysis on the efficacy of epidural corticosteroids in the treatment of sciatica. Anaesth Intensive Care 1995; 23: 564-9.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Airaksinen O., Brox J.I., Cedraschi C. et al. European guidelines for the management of chronic nonspecific low back pain. Eur Spine J 2006; 15(2): 192-300.&lt;/p&gt;&lt;p&gt;Andersson G.B.J. The epidemiology of spinal disorders. In: Frymoyer J.W., ed. The adult spine: principles and practice. 2nd ed. New York: Raven Press, 1997; 93-141.&lt;/p&gt;&lt;p&gt;Frymoyer J.W. Back pain and sciatica. N Engl J Med 1988; 318: 291-300.&lt;/p&gt;&lt;p&gt;Royal College of General Practitioners. Clinical Guidelines for the Management of Acute Low Back Pain. London: Royal College of General Practitioners, 1996 and 1999.&lt;/p&gt;&lt;p&gt;Hoogendoorn W.E., van Poppel M.N.M., Bongers P.M. et al. Systemic review of psychosocial factors at work and private life as risk factors for back pain. Spine 2000; 25: 2114-25.&lt;/p&gt;&lt;p&gt;Linton S.J. A review of psychological risk factors in back and neck pain. Spine 2000; 25: 1148-56.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Assendelft W.J.J., Koes B.W. et al. Spinal radiographic findings and nonspecific low back pain: a systematic review of observational studies. Spine 1997; 22: 427-34.&lt;/p&gt;&lt;p&gt;Jarvik J.G., Hollingworth W., Martin B. et al. Rapid magnetic resonance imaging vs radiographs for patients with low back pain: a randomized controlled trial. JAMA 2003; 289: 2810-8.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Koes B.W., Bouter L.M. Conservative treatment of acute and chronic nonspecific low back pain: a systematic review of randomized controlled trials of the most common interventions. Spine 1997; 22: 2128-56.&lt;/p&gt;&lt;p&gt;De Craen A.J.M., Di Giulio G., Lampe- Schoenmaeckers A.J.E.M. et al. Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: a systematic review. Br Med J 1996; 313: 321-5.&lt;/p&gt;&lt;p&gt;Koes B.W., Scholten R.J.P.M., Mens J.M.A. et al. Efficacy of non-steroidal anti-inflammatory drugs for low back pain: a systematic review of randomised clinical trials. Ann Rheum Dis 1997; 56: 214-23.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Scholten R.J.P.M., Koes B.W. et al. Non-steroidal anti-inflammatory drugs (NSAIDs) for non-specific low back pain (Cochrane Review). In: The Cochrane Library, Issue 4, Oxford: Update Software 2000.&lt;/p&gt;&lt;p&gt;Henry D., Lim L.L.Y., Rodriguez L.A.G. et al. Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis. Br Med J 1996; 312: 1563-6.&lt;/p&gt;&lt;p&gt;Van Tulder M.W., Touray T., Furlan A.D. et al. Muscle relaxants for non-specific low back pain (Cochrane Review). In: The Cochrane Library, Issue 1. Chichester, UK: John Wiley &amp;amp; Sons, Ltd, 2004.15.&lt;/p&gt;&lt;p&gt;Bigos S., Bowyer O., Braen G. et al. Acute low back problems in adults. Clinical practice guideline no. 14. AHCPR publication no. 95-0642. Rockville, MD: Agency for Health Care Policy and Research, Public Health Service, U.S. Department of health and Human Services. December 1994.&lt;/p&gt;&lt;p&gt;Van Tulder M., Becker A., Bekkering T. et al. European guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J 2006; 15(Suppl. 2): 169-91.&lt;/p&gt;&lt;p&gt;Данилов А.Б. Возможности применения тизанидина (сирдалуда) в клинической практике. Обзор литературы. РМЖ 2009; 17 (20): 1370.&lt;/p&gt;&lt;p&gt;Coward D.M. Tizanidine: Neuropharmacology and mechanism of action. Neurology 1994; 44(Suppl. 9): 6-11.&lt;/p&gt;&lt;p&gt;Hutchinson D.R., Daniels F. A multinational study in general practice to evaluate the effectiveness and tolerability of tizanidine in the treatment of painful muscle spasms. Br J Clin Res 1990; 1: 39-48.&lt;/p&gt;&lt;p&gt;Berry H., Hutchinson D.R. Tizanidine and ibuprofen in acute low-back pain: Results of a double-blind multicentre study in general practice. J Intern Med Res 1988; 16: 83-91.&lt;/p&gt;&lt;p&gt;Sirdalud Ternilin Asia-Pacific Study group. Efficacy and gastroprotective effects of tizanidine plus diclofenac versus placebo plus diclofenac in patients with painful muscle spasm. Curr Ther Res 1998; 59: 13-22.&lt;/p&gt;&lt;p&gt;Бадокин В.В. Применение сирдалуда в ревматологической практике. РМЖ 2005; 13(24): 1588-9.&lt;/p&gt;&lt;p&gt;Bettucci D., Testa L., Calzoni S. et al. Combination of tizanidine and amitriptyline in the prophylaxis of chronic tension - type headache: evaluation of efficacy and impact on quality of life. J Headache Pain 2006; 7(1): 34-6.&lt;/p&gt;&lt;p&gt;Воробьева О.В. Возможности альфа2- адренергических агонистов в лечении миофасциальной боли. РМЖ 2007; 5: 445-8.&lt;/p&gt;&lt;p&gt;McCleane G.J. Does Gabapentin have an analgesic effect on background, movement and referred pain? A randomised, doubleblind, placebo controlled study. Pain Clinic 2001; 13: 103-7.&lt;/p&gt;&lt;p&gt;Keitel W., Frerick H., Kuhn U. et al. Capsicum pain plaster in chronic non-specific low back pain. Arzneimittelforschung 2001; 51(11): 896-903.&lt;/p&gt;&lt;p&gt;Frerick H., Keitel W., Kuhn U. et al. Topical treatment of chronic low back pain with a capsicum plaster. Pain 2003; 106(1- 2): 59-64.&lt;/p&gt;&lt;p&gt;Koes B.W., Scholten R.J.P.M., Mens J.M.A. et al. Epidural steroid injections for low back pain and sciatica: an updated systematic review of randomized clinical trials. Pain Digest 1999; 9: 241-7.&lt;/p&gt;&lt;p&gt;Nelemans P.J., de Bie R.A., de Vet H.C.W. et al. Injection therapy for subacute and chronic benign low back pain. In: The Cochrane Library, Issue 4. Oxford: Update Software, 2001.&lt;/p&gt;&lt;p&gt;Watts R.W., Silagy C.A. A meta-analysis on the efficacy of epidural corticosteroids in the treatment of sciatica. Anaesth Intensive Care 1995; 23: 564-9.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
