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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2011-674</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-359</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Вопросы безопасности и фармакоэкономики при лечении хронической боли в спине и конечностях</article-title><trans-title-group xml:lang="en"><trans-title>The issues of safety and pharmacoeconomics in the management of chronic pain in the back and limbs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Парфенов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Parfenov</surname><given-names>Vladimir Anatol'evich</given-names></name></name-alternatives><email xlink:type="simple">vladimirparfenov@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimova</surname><given-names>O N</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Парфенов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Parfenov</surname><given-names>Vladimir Anatolyevich</given-names></name></name-alternatives><email xlink:type="simple">vladimirparfenov@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimova</surname><given-names>O N</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>14</day><month>06</month><year>2011</year></pub-date><volume>5</volume><issue>2</issue><issue-title>№2 (2011)</issue-title><fpage>77</fpage><lpage>80</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Парфенов В.А., Герасимова О.Н., Парфенов В.А., Герасимова О.Н., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Парфенов В.А., Герасимова О.Н., Парфенов В.А., Герасимова О.Н.</copyright-holder><copyright-holder xml:lang="en">Parfenov V.A., Gerasimova O.N., Parfenov V.A., Gerasimova O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/359">https://mrj.ima-press.net/mrj/article/view/359</self-uri><abstract><p>Для лечения хронической боли в спине и конечностях широко используются нестероидные противовоспалительные препараты (НПВП), длительный прием которых связан с риском осложнений, особенно со стороны желудочно-кишечного тракта (ЖКТ). Представлен обзор литературы, посвященной побочным эффектам, возникающим при лечении НПВП, обсуждаются вопросы фармакоэкономики при использовании различных НПВП. Отмечается, что применение селективного ингибитора циклооксигеназы 2 мелоксикама (мовалиса) вызывает меньше побочных эффектов со стороны ЖКТ, чем прием стандартных НПВП, при этом снижаются затраты на лечение осложнений со стороны ЖКТ.</p></abstract><trans-abstract xml:lang="en"><p>Nonsteroidal anti-inflammatory drugs (NSAIDs), the long-term administration of which is associated with a risk for complications, gastrointestinal tract (GIT) ones in particular, are extensively used to treat chronic pain in the back and limbs. The paper reviews the data available in the literature on adverse reactions occurring with the use of NSAIDs, discusses the issues of pharmacoeconomics in the administration of various NSAIDs. The use of the selective cyclooxygenase-2 inhibitor meloxicam (Movalis) is noted to cause fewer GIT adverse reactions than that of standard NSAIDs, the cost of treatment for GIT complications reduces.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая боль в спине и конечностях</kwd><kwd>нестероидные противовоспалительные препараты</kwd><kwd>мелокикам (мовалис)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic pain in the back and limbs</kwd><kwd>nonsteroidal anti-inflammatory drugs</kwd><kwd>meloxicam (movalis)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru"></mixed-citation><mixed-citation xml:lang="en"></mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
