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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2012-707</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-392</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Лечение больных псориатическим артритом. Рекомендации Европейской антиревматической лиги</article-title><trans-title-group xml:lang="en"><trans-title>Management of patients with psoriatic arthritis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корсакова</surname><given-names>Ю. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Korsakova</surname><given-names>Yulia Leonidovna</given-names></name></name-alternatives><email xlink:type="simple">_julia_06@mail.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2012</year></pub-date><volume>6</volume><issue>1</issue><issue-title>№1 (2012)</issue-title><fpage>5</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корсакова Ю.Л., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Корсакова Ю.Л.</copyright-holder><copyright-holder xml:lang="en">Korsakova Y.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/392">https://mrj.ima-press.net/mrj/article/view/392</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Kavanaugh A., Antoni C.E., Gladman D. et al. The Infliximab Multinational Psoriatic Arthritis Controlled Trial (IMPACT): results of radiographic analyses after 1 year. Ann Rheum Dis 2006; 65: 1038-43.&lt;/p&gt;&lt;p&gt;Mease P.J., Goffe B.S., Metz J. et al. Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Lancet 2000; 356: 385-90.&lt;/p&gt;&lt;p&gt;Antoni C., Krueger G.G., de Vlam K. et al. Infliximab improves signs and symptoms of psoriatic arthritis: results of the IMPACT 2 trial. Ann Rheum Dis 2005; 64: 1150-7.&lt;/p&gt;&lt;p&gt;Kaltwasser J.P., Nash P., Gladman D. et al. Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: a multinational, double-blind, randomized, placebo-controlled clinical trial. Arthr Rheum 2004; 50: 1939-50.&lt;/p&gt;&lt;p&gt;Mease P.J., Gladman D.D., Ritchlin C.T. et al. Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double-blind, randomized, placebo-controlled trial. Arthr Rheum 2005; 52: 3279-89.&lt;/p&gt;&lt;p&gt;Kavanaugh A., McInnes I., Mease P. et al. Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: twenty-four-week efficacy and safety results of a randomized, placebo-controlled study. Arthr Rheum 2009; 60: 976-86.&lt;/p&gt;&lt;p&gt;Mease P.J., Gladman D.D., Keystone E.C. Alefacept in combination with methotrexate for the treatment of psoriatic arthritis: results of a randomized, double-blind, placebocontrolled study. Arthr Rheum 2006; 54: 1638-45.&lt;/p&gt;&lt;p&gt;Menter A., Korman N.J., Elmets C.A. et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 4.Guidelines of care for the management and treatment of psoriasis with traditional systemic agents. J Am Acad Dermatol 2009; 61: 451-85.&lt;/p&gt;&lt;p&gt;Jones G., Crotty M., Brooks P. Interventions for psoriatic arthritis. Cochrane Database Syst Rev 2000; 3: CD000212.&lt;/p&gt;&lt;p&gt;Gottlieb A., Menter A., Mendelsohn A. et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebocontrolled, crossover trial. Lancet 2009; 373: 633-40.&lt;/p&gt;&lt;p&gt;Peeters A.J., Dijkmans B.A., van der Schroeff J.G. Fumaric acid therapy for psoriatic arthritis. A randomized, double-blind, placebo-controlled study. Br J Rheum 1992; 31: 502-4.&lt;/p&gt;&lt;p&gt;Menter A., Korman N.J., Elmets C.A. et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. J Am Acad Dermatol 2010; 62: 114-35.&lt;/p&gt;&lt;p&gt;Wright V., Moll J.M. Psoriatic arthritis. Bull Rheum Dis 1971; 21: 627-32.&lt;/p&gt;&lt;p&gt;Van den Bosch F., Cryssen B.V., Mielants H. Clinical assessment in the spondy loarthropathies, including psoriatic arthritis. Curr Opin Rheumatol 2006; 18: 354-8.&lt;/p&gt;&lt;p&gt;McGonagle D., Conaghan P.G., Emery P. Psoriatic arthritis: a unified concept twenty years on. Arthr Rheum 1999; 42: 1080-6.&lt;/p&gt;&lt;p&gt;Antoni C.E., Kavanaugh A., Kirkham B. et al. Sustained benefits of infliximab therapy for dermatologic and articular manifestations of psoriatic arthritis: results from the infliximab multinational psoriatic arthritis controlled trial (IMPACT). Arthr Rheum 2005; 52: 1227-36.&lt;/p&gt;&lt;p&gt;Gladman D.D., Mease P.J., Ritchlin C.T. et al. Adalimumab for long-term treatment of psoriatic arthritis: forty-eight week data from the adalimumab effectiveness in psoriatic arthritis trial. Arthr Rheum 2007; 56: 476-88.&lt;/p&gt;&lt;p&gt;Gladman D.D., Mease P.J., Cifaldi M.A. et al. Adalimumab improves joint-related and skin-related functional impairment in patients with psoriatic arthritis: patient-reported outcomes of the Adalimumab Effectiveness in Psoriatic Arthritis Trial. Ann Rheum Dis 2007; 66: 163-8.&lt;/p&gt;&lt;p&gt;Furst D.E., Keystone E.C., Fleischmann R. et al. Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2009. Ann Rheum Dis 2010; 69(Suppl. 1): i2—29.&lt;/p&gt;&lt;p&gt;Ritchlin C.T., Kavanaugh A., Gladman D.D. et al. Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 2009; 68: 1387-94.&lt;/p&gt;&lt;p&gt;Kavanaugh A.F., Ritchlin C.T. Systematic review of treatments for psoriatic arthritis: an evidence based approach and basis for treatment guidelines. J Rheum 2006; 33: 1417-21.&lt;/p&gt;&lt;p&gt;Fraser A.D., van Kuijk A.W., Westhovens R. et al. A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis. Ann Rheum Dis 2005; 64: 859-64.&lt;/p&gt;&lt;p&gt;Gladman D.D., Mease P.J., Healy P. et al. Outcome measures in psoriatic arthritis. J Rheum 2007; 34: 1159-66.&lt;/p&gt;&lt;p&gt;Kivitz A.J., Espinoza L.R., Sherrer Y.R. et al. A comparison of the efficacy and safety of celecoxib 200 mg and celecoxib 400 mg once daily in treating the signs and symptoms of psoriatic arthritis. Sem Arthr Rheum 2007; 37: 164-73.&lt;/p&gt;&lt;p&gt;Sarzi-Puttini P., Santandrea S., Boccassini L. et al. The role of NSAIDs in psoriatic arthritis: evidence from a controlled study with nimesulide. Clin Exp Rheum 2001; 19(1 Suppl. 22): S17-20.&lt;/p&gt;&lt;p&gt;Borer J.S., Simon L.S. Cardiovascular and gastrointestinal effects of COX-2 inhibitors and NSAIDs: achieving a balance. Arthr Res Ther 2005; 7(Suppl. 4): S14-22.&lt;/p&gt;&lt;p&gt;Latimer N., Lord J., Grant R.L. et al. Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis. BMJ 2009; 339: b2538.&lt;/p&gt;&lt;p&gt;Strand V. Are COX-2 inhibitors preferable to non-selective non-steroidal antiinflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin? Lancet 2007; 370: 2138-51.&lt;/p&gt;&lt;p&gt;Gladman D.D., Farewell V.T. Progression in psoriatic arthritis: role of time varying clinical indicators. J Rheum 1999; 26: 2409-13.&lt;/p&gt;&lt;p&gt;Lard L.R., Visser H., Speyer I. et al. Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. Am J Med 2001; 111: 446-51.&lt;/p&gt;&lt;p&gt;Scarpa R., Peluso R., Atteno M. et al. The effectiveness of a traditional therapeutical approach in early psoriatic arthritis: results of a pilot randomised 6-month trial with methotrexate. Clin Rheum 2008; 27: 823-6.&lt;/p&gt;&lt;p&gt;Lie E., van der Heijde D., Uhlig T. et al. Effectiveness and retention rates of methotrexate in psoriatic arthritis in comparison with methotrexate-treated patients with rheumatoid arthritis. Ann Rheum Dis 2010; 69: 671-6.&lt;/p&gt;&lt;p&gt;Black R.L., O'Brien W.M., Vanscott E.J. et al. Methotrexate therapy in psoriatic arthritis; double-blind study on 21 patients. JAMA 1964; 189: 743-7.&lt;/p&gt;&lt;p&gt;Visser K., van der Heijde D. Optimal dosage and route of administration of methotrexate in rheumatoid arthritis: a systematic review of the literature. Ann Rheum Dis 2009; 68: 1094-9.&lt;/p&gt;&lt;p&gt;Gupta A.K., Grober J.S., Hamilton T.A. et al. Sulfasalazine therapy for psoriatic arthritis: a double blind, placebo controlled trial. J Rheum 1995; 22: 894-8.&lt;/p&gt;&lt;p&gt;Salvarani C., Macchioni P., Olivieri I. et al. A comparison of cyclosporine, sulfasalazine, and symptomatic therapy in the treatment of psoriatic arthritis. J Rheum 2001; 28: 2274-82.&lt;/p&gt;&lt;p&gt;Clark C.M., Kirby B., Morris A.D. et al. Combination treatment with methotrexate and cyclosporin for severe recalcitrant psoriasis. Br J Dermatol 1999; 141: 279-82.&lt;/p&gt;&lt;p&gt;Helliwell P.S., Taylor W.J. Treatment of psoriatic arthritis and rheumatoid arthritis with disease modifying drugs - comparison of drugs and adverse reactions. J Rheum 2008; 35: 472-6.&lt;/p&gt;&lt;p&gt;Rosenberg P., Urwitz H., Johannesson A. et al. Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment. J Hepatol 2007; 46: 1111-18.&lt;/p&gt;&lt;p&gt;Heydendael V.M., Spuls P.I., Opmeer B.C. et al. Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis. N Engl J Med 2003; 349: 658-65.&lt;/p&gt;&lt;p&gt;Eder L., Chandran V., Ueng J. et al. Predictors of response to intra-articular steroid injection in psoriatic arthritis. Rheumatology (Oxford) 2010; 49: 1367-73.&lt;/p&gt;&lt;p&gt;Ritchlin C.T., Kavanaugh A., Gladman D.D. et al. Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 2009; 68: 1387-94.&lt;/p&gt;&lt;p&gt;Fredriksson T., Pettersson U. Severe psoriasis - oral therapy with a new retinoid. Dermatologica 1978; 157: 238-44.&lt;/p&gt;&lt;p&gt;Zink A., Thiele K., Huscher D. et al. Healthcare and burden of disease in psoriatic arthritis. A comparison with rheumatoid arthritis and ankylosing spondylitis. J Rheum 2006; 33: 86-90.&lt;/p&gt;&lt;p&gt;Hoes J.N., Jacobs J.W., Verstappen S.M. et al. A dverse events of low- to mediumdose oral glucocorticoids in inflammatory diseases: a meta-analysis. Ann Rheum Dis 2009; 68: 1833-8.&lt;/p&gt;&lt;p&gt;Antoni C.E., Kavanaugh A., Kirkham B. et al. Sustained benefits of infliximab therapy for dermatologic and articular manifestations of psoriatic arthritis: results from the infliximab multinational psoriatic arthritis controlled trial (IMPACT). Arthr Rheum 2005; 52: 1227-36.&lt;/p&gt;&lt;p&gt;Griffiths C.E., Strober B.E., van de Kerkhof P. et al. Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. N Engl J Med 2010; 362: 118-28.&lt;/p&gt;&lt;p&gt;Ash Z. A systematic literature review of conventional and biologic drug therapies for the treatment of psoriatic arthritis: current evidence informing the EULAR recommendations for the management of Psoriatic Arthritis. Ann Rheum Dis 2012; 71(3): 319—26.&lt;/p&gt;&lt;p&gt;Heiberg M.S., Koldingsnes W., Mikkelsen K. et al. The comparative one-year performance of anti-tumor necrosis factor alpha drugs in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: results from a longitudinal, observational, multicenter study. Arthr Rheum 2008; 59: 234-40.&lt;/p&gt;&lt;p&gt;Mease P.J., Ory P., Sharp J.T. et al. Adalimumab for long-term treatment of psoriatic arthritis: 2-year data from the Adalimumab Effectiveness in Psoriatic Arthritis Trial (ADEPT). Ann Rheum Dis 2009; 68: 702-9.&lt;/p&gt;&lt;p&gt;Mease P.J., Kivitz A.J., Burch F.X. et al. Continued inhibition of radiographic progression in patients with psoriatic arthritis following 2 years of treatment with etanercept. J Rheum 2006; 33: 712-21.&lt;/p&gt;&lt;p&gt;Antoni C.E., Kavanaugh A., van der Heijde D. et al. Two-year efficacy and safety of infliximab treatment in patients with active psoriatic arthritis: findings of the Infliximab Multinational Psoriatic Arthritis Controlled Trial (IMPACT). J Rheum 2008; 35: 869-76.&lt;/p&gt;&lt;p&gt;Zochling J., van der Heijde D., Burgos-Vargas R. et al. ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2006; 65: 442-52.&lt;/p&gt;&lt;p&gt;Braun J., Davis J., Dougados M. et al. First update of the international ASAS consensus statement for the use of anti-TNF agents in patients with ankylosing spondylitis. Ann Rheum Dis 2006; 65: 316-20.&lt;/p&gt;&lt;p&gt;Braun J., Pham T., Sieper J. et al. International ASAS consensus statement for the use of anti-tumour necrosis factor agents in patients with ankylosing spondylitis. Ann Rheum Dis 2003; 62: 817-24.&lt;/p&gt;&lt;p&gt;Gomez-Reino J.J., Carmona L. Switching TNF antagonists in patients with chronic arthritis: an observational study of 488 patients over a four-year period. Arthr Res Ther 2006; 8: R29.&lt;/p&gt;&lt;p&gt;Saad A.A., Ashcroft D.M., Watson K.D. et al. Persistence with anti-tumour necrosis factor therapies in patients with psoriatic arthritis: observational study from the British Society of Rheumatology Biologics Register. Arthr Res Ther 2009; 11: R52.&lt;/p&gt;&lt;p&gt;Tam L.S., Tomlinson B., Chu T.T. et al. Cardiovascular risk profile of patients with psoriatic arthritis compared to controls - the role of inflammation. Rheumatology (Oxford) 2008; 47: 718-23.&lt;/p&gt;&lt;p&gt;Бадокин В.В., Корсакова Ю.Л., Барскова В.Г. и др. Терапия псориатического артрита инфликсимабом. Совр ревматол 2009; 1: 29-35.&lt;/p&gt;&lt;p&gt;Gossec L., Smolen J.S., Gaujoux-Viala C. et al. European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Ann Rheum Dis 2012; 71: 4-12.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Kavanaugh A., Antoni C.E., Gladman D. et al. The Infliximab Multinational Psoriatic Arthritis Controlled Trial (IMPACT): results of radiographic analyses after 1 year. Ann Rheum Dis 2006; 65: 1038-43.&lt;/p&gt;&lt;p&gt;Mease P.J., Goffe B.S., Metz J. et al. Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Lancet 2000; 356: 385-90.&lt;/p&gt;&lt;p&gt;Antoni C., Krueger G.G., de Vlam K. et al. Infliximab improves signs and symptoms of psoriatic arthritis: results of the IMPACT 2 trial. Ann Rheum Dis 2005; 64: 1150-7.&lt;/p&gt;&lt;p&gt;Kaltwasser J.P., Nash P., Gladman D. et al. Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: a multinational, double-blind, randomized, placebo-controlled clinical trial. Arthr Rheum 2004; 50: 1939-50.&lt;/p&gt;&lt;p&gt;Mease P.J., Gladman D.D., Ritchlin C.T. et al. Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double-blind, randomized, placebo-controlled trial. Arthr Rheum 2005; 52: 3279-89.&lt;/p&gt;&lt;p&gt;Kavanaugh A., McInnes I., Mease P. et al. Golimumab, a new human tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: twenty-four-week efficacy and safety results of a randomized, placebo-controlled study. Arthr Rheum 2009; 60: 976-86.&lt;/p&gt;&lt;p&gt;Mease P.J., Gladman D.D., Keystone E.C. Alefacept in combination with methotrexate for the treatment of psoriatic arthritis: results of a randomized, double-blind, placebocontrolled study. Arthr Rheum 2006; 54: 1638-45.&lt;/p&gt;&lt;p&gt;Menter A., Korman N.J., Elmets C.A. et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 4.Guidelines of care for the management and treatment of psoriasis with traditional systemic agents. J Am Acad Dermatol 2009; 61: 451-85.&lt;/p&gt;&lt;p&gt;Jones G., Crotty M., Brooks P. Interventions for psoriatic arthritis. Cochrane Database Syst Rev 2000; 3: CD000212.&lt;/p&gt;&lt;p&gt;Gottlieb A., Menter A., Mendelsohn A. et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebocontrolled, crossover trial. Lancet 2009; 373: 633-40.&lt;/p&gt;&lt;p&gt;Peeters A.J., Dijkmans B.A., van der Schroeff J.G. Fumaric acid therapy for psoriatic arthritis. A randomized, double-blind, placebo-controlled study. Br J Rheum 1992; 31: 502-4.&lt;/p&gt;&lt;p&gt;Menter A., Korman N.J., Elmets C.A. et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. J Am Acad Dermatol 2010; 62: 114-35.&lt;/p&gt;&lt;p&gt;Wright V., Moll J.M. Psoriatic arthritis. Bull Rheum Dis 1971; 21: 627-32.&lt;/p&gt;&lt;p&gt;Van den Bosch F., Cryssen B.V., Mielants H. Clinical assessment in the spondy loarthropathies, including psoriatic arthritis. Curr Opin Rheumatol 2006; 18: 354-8.&lt;/p&gt;&lt;p&gt;McGonagle D., Conaghan P.G., Emery P. Psoriatic arthritis: a unified concept twenty years on. Arthr Rheum 1999; 42: 1080-6.&lt;/p&gt;&lt;p&gt;Antoni C.E., Kavanaugh A., Kirkham B. et al. Sustained benefits of infliximab therapy for dermatologic and articular manifestations of psoriatic arthritis: results from the infliximab multinational psoriatic arthritis controlled trial (IMPACT). Arthr Rheum 2005; 52: 1227-36.&lt;/p&gt;&lt;p&gt;Gladman D.D., Mease P.J., Ritchlin C.T. et al. Adalimumab for long-term treatment of psoriatic arthritis: forty-eight week data from the adalimumab effectiveness in psoriatic arthritis trial. Arthr Rheum 2007; 56: 476-88.&lt;/p&gt;&lt;p&gt;Gladman D.D., Mease P.J., Cifaldi M.A. et al. Adalimumab improves joint-related and skin-related functional impairment in patients with psoriatic arthritis: patient-reported outcomes of the Adalimumab Effectiveness in Psoriatic Arthritis Trial. Ann Rheum Dis 2007; 66: 163-8.&lt;/p&gt;&lt;p&gt;Furst D.E., Keystone E.C., Fleischmann R. et al. Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2009. Ann Rheum Dis 2010; 69(Suppl. 1): i2—29.&lt;/p&gt;&lt;p&gt;Ritchlin C.T., Kavanaugh A., Gladman D.D. et al. Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 2009; 68: 1387-94.&lt;/p&gt;&lt;p&gt;Kavanaugh A.F., Ritchlin C.T. Systematic review of treatments for psoriatic arthritis: an evidence based approach and basis for treatment guidelines. J Rheum 2006; 33: 1417-21.&lt;/p&gt;&lt;p&gt;Fraser A.D., van Kuijk A.W., Westhovens R. et al. A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis. Ann Rheum Dis 2005; 64: 859-64.&lt;/p&gt;&lt;p&gt;Gladman D.D., Mease P.J., Healy P. et al. Outcome measures in psoriatic arthritis. J Rheum 2007; 34: 1159-66.&lt;/p&gt;&lt;p&gt;Kivitz A.J., Espinoza L.R., Sherrer Y.R. et al. A comparison of the efficacy and safety of celecoxib 200 mg and celecoxib 400 mg once daily in treating the signs and symptoms of psoriatic arthritis. Sem Arthr Rheum 2007; 37: 164-73.&lt;/p&gt;&lt;p&gt;Sarzi-Puttini P., Santandrea S., Boccassini L. et al. The role of NSAIDs in psoriatic arthritis: evidence from a controlled study with nimesulide. Clin Exp Rheum 2001; 19(1 Suppl. 22): S17-20.&lt;/p&gt;&lt;p&gt;Borer J.S., Simon L.S. Cardiovascular and gastrointestinal effects of COX-2 inhibitors and NSAIDs: achieving a balance. Arthr Res Ther 2005; 7(Suppl. 4): S14-22.&lt;/p&gt;&lt;p&gt;Latimer N., Lord J., Grant R.L. et al. Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis. BMJ 2009; 339: b2538.&lt;/p&gt;&lt;p&gt;Strand V. Are COX-2 inhibitors preferable to non-selective non-steroidal antiinflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin? Lancet 2007; 370: 2138-51.&lt;/p&gt;&lt;p&gt;Gladman D.D., Farewell V.T. Progression in psoriatic arthritis: role of time varying clinical indicators. J Rheum 1999; 26: 2409-13.&lt;/p&gt;&lt;p&gt;Lard L.R., Visser H., Speyer I. et al. Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. 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Ann Rheum Dis 2012; 71: 4-12.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
