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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2014-1-27-30</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-507</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Интерстициальное поражение легких у больной ревматоидным артритом</article-title><trans-title-group xml:lang="en"><trans-title>Interstitial lung disease in a female patient with rheumatoid arthritis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аверкиева</surname><given-names>Юлия Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Averkieva</surname><given-names>Yuliya Valeryavna</given-names></name></name-alternatives><email xlink:type="simple">doctorjulia@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раскина</surname><given-names>Татьяна Алексеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Raskina</surname><given-names>T A</given-names></name></name-alternatives><email xlink:type="simple">doctorjulia@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малышенко</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyshenko</surname><given-names>O S</given-names></name></name-alternatives><email xlink:type="simple">doctorjulia@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волыкова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volykova</surname><given-names>M A</given-names></name></name-alternatives><email xlink:type="simple">doctorjulia@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маслова</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Maslova</surname><given-names>O M</given-names></name></name-alternatives><email xlink:type="simple">doctorjulia@rambler.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Кемеровская государственная медицинская академия» Минздрава России, Кемерово, Россия; 650029, Кемерово, ул. Ворошилова, 22А</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kemerovo State Medical Academy, Ministry of Healthcare of the Russian Federation, Kemerovo, Russia; Voroshilova ul.. 22A, Kemerovo, 650029 Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ КО «Областной клинический госпиталь для ветеранов войн», Кемерово, Россия; 650000, Кемерово, ул. 50 лет Октября, 10</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital for War Veterans, Kemerovo, Russia; 50 let Oktyabrya ul., Kemerovo, 650000 Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ КО «Областная клиническая больница», Кемерово, Россия; 650000, Кемерово, пр. Октябрьский, 22</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital, Kemerovo, Russia; pr. Oktyabr’skiy, 22, Kemerovo, 650000 Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2014</year></pub-date><volume>8</volume><issue>1</issue><issue-title>№1 (2014)</issue-title><fpage>27</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аверкиева Ю.В., Раскина Т.А., Малышенко О.С., Волыкова М.А., Маслова О.М., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Аверкиева Ю.В., Раскина Т.А., Малышенко О.С., Волыкова М.А., Маслова О.М.</copyright-holder><copyright-holder xml:lang="en">Averkieva Y.V., Raskina T.A., Malyshenko O.S., Volykova M.A., Maslova O.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/507">https://mrj.ima-press.net/mrj/article/view/507</self-uri><abstract><p>Ревматоидный артрит (РА) характеризуется прогрессирующим течением с формированием деформаций суставов, развитием тяжелых функциональных нарушений. В то же время при этом заболевании часто встречаются и системные воспалительные поражения внутренних органов, которые могут стать причиной существенного ухудшения качества жизни, трудоспособности и в значительной мере определять прогноз. Особое внимание привлекают идиопатические интерстициальные пневмонии (ИИП), отличающиеся неблагоприятным прогнозом вследствие неуклонно прогрессирующей фиброзной перестройки легкого. В статье приводится клинический случай РА, при котором наблюдалась картина интерстициального поражения легких.</p></abstract><trans-abstract xml:lang="en"><p>Rheumatoid arthritis (RA) is a progressive disease, resulting in joint deformation and development of severe functional disorders. Meanwhile, RA patients frequently have systemic inflammatory disorders of internal organs, which may significantly worsen quality of life, labor capacity, and be a factor determining the prognosis. Idiopathic interstitial pneumonia is of particular interest. This disease is characterized by unfavorable prognosis due to progressive fibrous rearrangement of the lung. We report a clinical case of RA with signs of interstitial lung disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматоидный артрит</kwd><kwd>интерстициальное поражение легких</kwd><kwd>обычная интерстициальная пневмония</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatoid arthritis</kwd><kwd>interstitial lung disease</kwd><kwd>usual interstitial pneumonia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Бестаев ДВ, Каратеев ДЕ, Насонов ЕЛ. Интерстициальное поражение легких при ревматоидном артрите. Научно-практическая ревматология. 2012;50(6):63–9. [Bestaev DV, Karateyev DE, Nasonov EL. Intersitial lung involvement in rheumatoid arthritis. Rheumatology Science and Practice. 2012;50(6):63–9.]. DOI: http://dx.doi.org/10.14412/1995-4484-2012-1296.&lt;/p&gt;&lt;p&gt;Сулимов ВА, Маколкин ВИ, Фоминых ЕВ и др. Бронхолегочные поражения при ревматоидном артрите. Лечащий врач. 2010;11:57–61. [Sulimov VA, Makolkin VI, Fominykh EV i dr. Bronkholegochnye porazheniya pri revmatoidnom artrite. Lechashchii vrach. 2010;11:57–61.]&lt;/p&gt;&lt;p&gt;Fathi M, Vikgren J, Boijsen M, et al. Interstitial lung disease in polymyositis and dermatomyositis: longitudinal evaluation by pulmonary function and radiology. Arthritis Rheum. 2008;59(5):677–85. DOI: 10.1002/art.23571.&lt;/p&gt;&lt;p&gt;Насонов ЕЛ, редактор. Ревматология. Национальное руководство. Москва: ГЭОТАР-Медиа; 2008. [Nasonov EL, redaktor. Revmatologiya. Natsional'noe rukovodstvo. Moskva: GEOTAR-Media; 2008.]&lt;/p&gt;&lt;p&gt;Bradley B, Branley HM, Egan JJ, et al. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax. 2008;63 Suppl 5:v1–v58. DOI: 10.1136/thx.2008.101691.&lt;/p&gt;&lt;p&gt;Richeldi L, Davies HR, Ferrara G, Franco F. Corticosteroids for idiopathic pulmonary fibrosis. Cohrane Database Syst Rev. 2003;(3):CD002880.&lt;/p&gt;&lt;p&gt;Hagiwara K, Sato T, Takagi-Kobayashi S, et al. Acute exacerbation of preexisting interstitial lung disease after administration of etanercept for rheumatoid arthritis. J Rheumatol. 2007;34(5):1151–4. Epub 2007 Apr 15.&lt;/p&gt;&lt;p&gt;Demedts M, Behr J, Buhl R, et al. Highdose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med. 2005;353(21):2229–42. DOI: http://dx.doi.org/10.1056/NEJMoa042976.&lt;/p&gt;&lt;p&gt;Gehr J, Maier K, Degenkolb B, et al. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Am J Respir Crit Care Med. 1997;156(6):1897–901. DOI: http://dx.doi.org/10.1164/ajrc-cm.156.6.9706065.&lt;/p&gt;&lt;p&gt;Насонов ЕЛ. Ревматоидный артрит как общемедицинская проблема. Терапевтический архив. 2004;76(5):5–7. [Nasonov EL. Rheumatoid arthritis as a general medical problem. Terapevticheskii arkhiv. 2004;76(5):5–7.]&lt;/p&gt;&lt;p&gt;Насонов ЕЛ, Насонова ВА. Ревматология: Национальное руководство. Москва: ГЭОТАР-Медиа, 2008. [Nasonov EL, Nasonova VA. Revmatologiya: Natsional'noe rukovodstvo. Moskva: GEOTAR-Media, 2008.]&lt;/p&gt;&lt;p&gt;Park JH, Kim DS, Park IN, et al. Prognosis of fibrotic interstitial pneumonia: idiopathic versus collagen vascular diseaserelated subtypes. Am J Respir Crit Care Med. 2007;175(7):705–11. DOI: http://dx.doi.org/10.1164/rccm.200607-912OC.&lt;/p&gt;&lt;p&gt;Dawson JK, Fewins HE, Desmond J, et al. Predictors of progression of HRCT diagnosed fibrosing alveolitis in patients with rheumatoid arthritis. Ann Rheum Dis. 2002;61(6):517–21. DOI: http://dx.doi.org/10.1136/ard.61.6.517.&lt;/p&gt;&lt;p&gt;Kinder BW, Collard HR, Koth L, et al. Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease? Am J Respir Crit Care Med. 2007;176(7):691–7. DOI: http://dx.doi.org/10.1164/rccm.200702-220OC. Epub 2007 Jun 7.&lt;/p&gt;&lt;p&gt;Steen VD, Conte C, Owens GR, Medsger TA Jr. Severe restrictive lung disease in systemic sclerosis. Arthritis Rheum. 1994;37(9):1283–9. DOI: http://dx.doi.org/10.1002/art.1780370903.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Бестаев ДВ, Каратеев ДЕ, Насонов ЕЛ. Интерстициальное поражение легких при ревматоидном артрите. Научно-практическая ревматология. 2012;50(6):63–9. [Bestaev DV, Karateyev DE, Nasonov EL. Intersitial lung involvement in rheumatoid arthritis. Rheumatology Science and Practice. 2012;50(6):63–9.]. DOI: http://dx.doi.org/10.14412/1995-4484-2012-1296.&lt;/p&gt;&lt;p&gt;Сулимов ВА, Маколкин ВИ, Фоминых ЕВ и др. Бронхолегочные поражения при ревматоидном артрите. Лечащий врач. 2010;11:57–61. [Sulimov VA, Makolkin VI, Fominykh EV i dr. Bronkholegochnye porazheniya pri revmatoidnom artrite. Lechashchii vrach. 2010;11:57–61.]&lt;/p&gt;&lt;p&gt;Fathi M, Vikgren J, Boijsen M, et al. Interstitial lung disease in polymyositis and dermatomyositis: longitudinal evaluation by pulmonary function and radiology. Arthritis Rheum. 2008;59(5):677–85. DOI: 10.1002/art.23571.&lt;/p&gt;&lt;p&gt;Насонов ЕЛ, редактор. Ревматология. Национальное руководство. Москва: ГЭОТАР-Медиа; 2008. [Nasonov EL, redaktor. Revmatologiya. Natsional'noe rukovodstvo. Moskva: GEOTAR-Media; 2008.]&lt;/p&gt;&lt;p&gt;Bradley B, Branley HM, Egan JJ, et al. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax. 2008;63 Suppl 5:v1–v58. DOI: 10.1136/thx.2008.101691.&lt;/p&gt;&lt;p&gt;Richeldi L, Davies HR, Ferrara G, Franco F. Corticosteroids for idiopathic pulmonary fibrosis. Cohrane Database Syst Rev. 2003;(3):CD002880.&lt;/p&gt;&lt;p&gt;Hagiwara K, Sato T, Takagi-Kobayashi S, et al. Acute exacerbation of preexisting interstitial lung disease after administration of etanercept for rheumatoid arthritis. J Rheumatol. 2007;34(5):1151–4. Epub 2007 Apr 15.&lt;/p&gt;&lt;p&gt;Demedts M, Behr J, Buhl R, et al. Highdose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med. 2005;353(21):2229–42. DOI: http://dx.doi.org/10.1056/NEJMoa042976.&lt;/p&gt;&lt;p&gt;Gehr J, Maier K, Degenkolb B, et al. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Am J Respir Crit Care Med. 1997;156(6):1897–901. DOI: http://dx.doi.org/10.1164/ajrc-cm.156.6.9706065.&lt;/p&gt;&lt;p&gt;Насонов ЕЛ. Ревматоидный артрит как общемедицинская проблема. Терапевтический архив. 2004;76(5):5–7. [Nasonov EL. Rheumatoid arthritis as a general medical problem. Terapevticheskii arkhiv. 2004;76(5):5–7.]&lt;/p&gt;&lt;p&gt;Насонов ЕЛ, Насонова ВА. Ревматология: Национальное руководство. Москва: ГЭОТАР-Медиа, 2008. [Nasonov EL, Nasonova VA. Revmatologiya: Natsional'noe rukovodstvo. Moskva: GEOTAR-Media, 2008.]&lt;/p&gt;&lt;p&gt;Park JH, Kim DS, Park IN, et al. Prognosis of fibrotic interstitial pneumonia: idiopathic versus collagen vascular diseaserelated subtypes. Am J Respir Crit Care Med. 2007;175(7):705–11. DOI: http://dx.doi.org/10.1164/rccm.200607-912OC.&lt;/p&gt;&lt;p&gt;Dawson JK, Fewins HE, Desmond J, et al. Predictors of progression of HRCT diagnosed fibrosing alveolitis in patients with rheumatoid arthritis. Ann Rheum Dis. 2002;61(6):517–21. DOI: http://dx.doi.org/10.1136/ard.61.6.517.&lt;/p&gt;&lt;p&gt;Kinder BW, Collard HR, Koth L, et al. Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease? Am J Respir Crit Care Med. 2007;176(7):691–7. DOI: http://dx.doi.org/10.1164/rccm.200702-220OC. Epub 2007 Jun 7.&lt;/p&gt;&lt;p&gt;Steen VD, Conte C, Owens GR, Medsger TA Jr. Severe restrictive lung disease in systemic sclerosis. Arthritis Rheum. 1994;37(9):1283–9. DOI: http://dx.doi.org/10.1002/art.1780370903.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
