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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2016-1-48-51</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-671</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИСКУССИОННЫЕ ВОПРОСЫ РЕВМАТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DEBATABLE PROBLEMS OF RHEUMATOLOGY</subject></subj-group></article-categories><title-group><article-title>Ремиссия при анкилозирующем спондилите и аксиальных спондилоартритах: современное понимание проблемы</article-title><trans-title-group xml:lang="en"><trans-title>Remission in ankylosing spondylitis and axial spondyloarthritides: A modern understanding of the problem</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайдукова</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaydukova</surname><given-names>I. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>410012, Саратов, ул. Большая Казачья, 112</p></bio><bio xml:lang="en"><p>112, Bolshaya Kazachya St., Saratov 410012</p></bio><email xlink:type="simple">ubp1976@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ребров</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rebrov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>410012, Саратов, ул. Большая Казачья, 112</p></bio><bio xml:lang="en"><p>112, Bolshaya Kazachya St., Saratov 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шувалова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shuvalova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>410012, Саратов, ул. Большая Казачья, 112</p></bio><bio xml:lang="en"><p>112, Bolshaya Kazachya St., Saratov 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Саратовский государственный медицинский университет им. В.И. Разумовского» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>24</day><month>03</month><year>2016</year></pub-date><volume>10</volume><issue>1</issue><fpage>48</fpage><lpage>51</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гайдукова И.З., Ребров А.П., Шувалова А.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Гайдукова И.З., Ребров А.П., Шувалова А.А.</copyright-holder><copyright-holder xml:lang="en">Gaydukova I.Z., Rebrov A.P., Shuvalova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/671">https://mrj.ima-press.net/mrj/article/view/671</self-uri><abstract><p>Обсуждаются возможные подходы к определению ремиссии при анкилозирующем спондилите (АС) и других аксиальных спондилоартритах (аксСпА).</p><p>В настоящее время единого определения понятия «ремиссия» при аксСпА и АС не существует, что обусловлено как разнообразием проявлений аксСпА и наличием большого числа инструментов оценки активности заболевания, так и неодновременным изменением выраженности клинических, лабораторных симптомов, признаков острого воспаления по данным визуализирующих методов и признаков прогрессирования структурных изменений опорно-двигательного аппарата у одного и того же пациента. У больного может не совпадать по времени клиническая, лабораторная, магнитно-резонансная и рентгенологическая ремиссия, что в свою очередь влияет на выбор оптимальной терапии.</p><p>На клиническом примере продемонстрированы сложности коррекции лечения у пациента, достигшего клинико-лабораторной ремиссии при сохраняющихся воспалительных явлениях в опорно-двигательном аппарате по данным визуализирующих методов. Так как рекомендации по наблюдению и лечению больных с нерентгенологическим аксСпА и АС сегодня не различаются, в статье рассматривается единая для всех подтипов аксСпА проблема ремиссии.</p></abstract><trans-abstract xml:lang="en"><p>The paper discusses possible approaches to determining remission in ankylosing spondylitis (AS) and other axial spondyloarthritides (axSpA). At present, there is no single definition of the concept of remission in axSpA and AS, which is due to both the diversity of manifestations of axSpA and a large number of tools to measure disease activity and the nonsimultaneous change in the degree of clinical and laboratory symptoms, signs of acute inflammation, as evidenced by imaging techniques, and signs of progressive structural changes in the locomotor apparatus in the same patient. Clinical, laboratory, magnetic resonance imaging, and radiographic remissions in a patient cannot be in time, which in turn affects the choice of optimal therapy.</p><p>The case report demonstrates problems with treatment correction in a patient who has achieved clinical and laboratory remission in the presence of persistent inflammatory signs in the locomotor apparatus, as shown by imaging techniques. Since the guidelines for the follow-up and treatment of patients with nonradiographic axSpA and AS are similar today, the paper considers remission as a general problem for all subtypes of axSpA.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аксиальный спондилоартрит</kwd><kwd>анкилозирующий спондилит</kwd><kwd>ремиссия</kwd><kwd>нестероидные противовоспалительные препараты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>axial spondyloarthritis</kwd><kwd>ankylosing spondylitis</kwd><kwd>remission</kwd><kwd>non-steroidal anti-inflammatory drugs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Braun J, Sieper J. Ankylosing spondylitis. Lancet. 2007 Apr 21;369(9570):1379-90.</mixed-citation><mixed-citation xml:lang="en">Braun J, Sieper J. Ankylosing spondylitis. 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