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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2016-1-63-66</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-674</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Влияние терапии ингибиторами фактора некроза опухоли α на трудоспособность больных анкилозирующим спондилитом</article-title><trans-title-group xml:lang="en"><trans-title>Impact of therapy with tumor necrosis factor-α inhibitors on the working ability of patients with ankylosing spondylitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эрдес</surname><given-names>Ш. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Erdes</surname><given-names>Sh. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115552</p></bio><email xlink:type="simple">erdes@irramn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подряднова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Podryadnova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115552</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>24</day><month>03</month><year>2016</year></pub-date><volume>10</volume><issue>1</issue><fpage>63</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Эрдес Ш.Ф., Подряднова М.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Эрдес Ш.Ф., Подряднова М.В.</copyright-holder><copyright-holder xml:lang="en">Erdes S.F., Podryadnova M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/674">https://mrj.ima-press.net/mrj/article/view/674</self-uri><abstract><p>Анкилозирующий спондилит (АС) – хроническое прогрессирующее заболевание, приводящее к инвалидизации. Поражая в основном лиц молодого и трудоспособного возраста, АС значительно сокращает трудовой потенциал общества. В настоящее время с учетом имеющихся данных можно утверждать, что длительная терапия больных АС ингибиторами фактора некроза опухоли α позволяет не только улучшить клиническое состояние, но и восстановить трудоспособность. Это, в свою очередь, позволяет сделать вывод, что непрямые расходы, связанные с данным заболеванием, значительно могут сократить медицинские потери общества (связанные с дорогостоящим лечением) по мере возвращения больных к активному труду.</p></abstract><trans-abstract xml:lang="en"><p>Ankylosing spondylitis (AS) is a chronic progressive disease resulting in disability. Affecting mainly young and able-bodied people, AS considerably reduces the manpower of society. To date, it may be stated on the basis of the available data, that long-term therapy with tumor necrosis factor-α inhibitors makes it possible not only to improve clinical status, but also to restore working ability. This in turn can lead to the conclusion that the indirect costs associated with this disease can substantially reduce costly treatment-related medical losses of society as the patients return to active labor.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>анкилозирующий спондилит</kwd><kwd>инвалидизация</kwd><kwd>терапия ингибиторами фактора некроза опухоли α</kwd><kwd>улучшение трудоспособности больных</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ankylosing spondylitis</kwd><kwd>disability</kwd><kwd>therapy with tumor necrosis factor-α inhibitors</kwd><kwd>improvement of patients’ working ability</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chorus AM, Miedema HS, Boonen A, Van Der Linden S. Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age. 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