References

mrj

Современная ревматология

Modern Rheumatology Journal

1996-70122310-158X

IMA-PRESS, LLC

10.14412/1996-7012-2016-3-69-76

mrj-704

Research Article

ОБЗОРЫ

REVIEWS

Инфекция, вызываемая вирусом Herpes zoster, и ревматические заболевания: современное состояние проблемы

Herpes zoster virus infection and rheumatic diseases: Current state of the problem

Буханова

Д. В.

Bukhanova

D. V.

rheumodaria@yandex.ru

Белов

Б. С.

Belov

B. S.

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», Москва, Россия 115522, Москва, Каширское шоссе, 34АРоссияV.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522Russian Federation

2016

26092016

1036976

2016

Буханова Д.В., Белов Б.С.

Bukhanova D.V., Belov B.S.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://mrj.ima-press.net/mrj/article/view/704

Настоящий обзор посвящен проблеме инфекции, вызываемой реактивацией вируса Herpes zoster (HZ), при ревматических заболеваниях (РЗ). По данным абсолютного большинства исследований, частота HZ-инфекции при РЗ превышает популяционную в 2–10 раз. В качестве факторов риска выделяют возраст, пол, прием глюкокортикоидов, длительность и тяжесть заболевания. Несомненно, важной является проблема вакцинации против HZ-инфекции пациентов с РЗ. На сегодняшний день представляет интерес изучение эффективности и безопасности новой адъювантной HZ/su-вакцины у пациентов с РЗ.

This review deals with infection caused by Herpes zoster (HZ) reactivation in rheumatic diseases (RD). The absolute majority of studies show that the incidence of HZ infection in RD is 2–10-fold higher than the population one. Patient age, gender, use of glucocorticoids, and duration and severity of the disease are identified as risk factors. Vaccination against HZ infection is sure to be important for patients with RD. Investigation of the efficacy and safety of a new adjuvant NZ/su vaccine in patients with RD is of interest today.

Herpes zosterкоморбидные инфекциикоморбидностьаутоиммунные ревматические заболеванияревматоидный артритсистемная красная волчанкадерматомиозитгенно-инженерные биологические препаратывакцинация.

Herpes zostercomorbid infectionscomorbidityautoimmune rheumatic diseasesrheumatoid arthritissystemic lupus erythematosusdermatomyositisbiological agentsvaccination

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The authors declare that there are no conflicts of interest present.