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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2016-4-51-56</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-719</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>КЛИНИЧЕСКАЯ ГЕТЕРОГЕННОСТЬ РАННЕГО ПСОРИАТИЧЕСКОГО АРТРИТА</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL HETEROGENEITY OF EARLY PSORIATIC ARTHRITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадокин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Badokin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Контакты: Владимир Васильевич Бадокин; ФГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России, 123836, Москва, Баррикадная ул., 2/1</p></bio><bio xml:lang="en"><p>Contact: Vladimir Vasilyevich Badokin;RussianMedicalAcademyof Postgraduate Education, Ministry of Health ofRussia, 2/1, Barrikadnaya St.,Moscow123836</p></bio><email xlink:type="simple">vbadokin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошкина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshkina</surname><given-names>I. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российская медицинская академия последипломного образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт ревматологии им. В.А. Насоновой</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>16</day><month>12</month><year>2016</year></pub-date><volume>10</volume><issue>4</issue><fpage>51</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бадокин В.В., Трошкина И.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Бадокин В.В., Трошкина И.А.</copyright-holder><copyright-holder xml:lang="en">Badokin V.V., Troshkina I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/719">https://mrj.ima-press.net/mrj/article/view/719</self-uri><abstract><p>Цель исследования – выявить характерные симптомы и синдромы ранней стадии псориатического артрита (рПсА), имеющие кардинальное значение для ранней диагностики этого заболевания.</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Обследован 51 больной с давностью ПсА до 2 лет (в среднем – 12 мес). Диагноз ПсА устанавливался на основании общепринятых критериев CASPAR и отечественных критериев, разработанных экспертным методом. Для выявления воспалительной активности использовали общепринятые современные критерии, включая число болезненных и припухших суставов, индекс DAS28, значения острофазовых показателей. Оценка кожного синдрома осуществлялась с использованием индекса PASI. Проводили рентгенографию кистей, дистальных и проксимальных отделов стоп, таза и других пораженных суставов, а также магнитно-резонансную томографию дистальных отделов кистей/стоп. Для оценки энтезопатии использовали индекс MASES и редуцированный счет GUESS.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлены варианты суставного синдрома рПсА в зависимости от длительности заболевания. Определены характерные особенности артрита, спондилита, энтезита, дактилита, их диагностическая значимость и ассоциации с другими проявлениями в первые 2 года ПсА. Определена взаимосвязь дерматита и псориатической онихопатии с клинической картиной суставного синдрома.</p></sec><sec><title>Выводы</title><p>Выводы. РПсА характеризуется выраженной гетерогенностью суставного синдрома с преимущественно моно/олигоартритическим и полиартритическим суставным синдромом. Значимыми признаками являются энтезит и дактилит, которые служат факторами риска неблагоприятного течения заболевания. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to reveal the characteristic symptoms and syndromes of early-stage psoriatic arthritis (ePsA), which are pivotal to its early diagnosis.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. Fifty-one patients with a PsA duration of less than 2 years (mean 12 months) were examined. The diagnosis of PsA was established on the basis of the conventional CASPAR criteria and the Russian criteria developed by the expert method. The conventional current criteria, including the number of tender and swollen joints, DAS28, values of acute-phase indicators, were used to detect inflammatory activity. Skin syndrome was evaluated using the Psoriasis Area and Severity Index (PASI). X-ray study of the hands, distal and proximal feet, pelvis, and other involved joints and MRI of the distal hands/feet were performed. The Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and reduced GUESS were used to assess enthesopathy.</p></sec><sec><title>Results</title><p>Results. The types of articular syndrome in ePsA were identified in accordance of the duration of the disease. The authors determined the characteristic features of arthritis, spondylitis, enthesitis, and dactylitis, their diagnostic value and associations with other manifestations in the first 2 years of PsA. There was a relationship of dermatitis and psoriatic onychopathy to the clinical picture of articular syndrome.</p></sec><sec><title>Conclusion</title><p>Conclusion. ePsA is characterized by marked heterogeneity of articular syndrome with predominantly mono/oligoarthritic and polyarthritic articular syndrome. The significant signs are enthesitis and dactylitis, which serve as risk factors for the unfavorable course of the disease. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ранний псориатический артрит</kwd><kwd>чувствительность симптомов</kwd><kwd>энтезит</kwd><kwd>дактилит</kwd><kwd>псориатический артрит</kwd><kwd>псориатический спондилит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>early psoriatic arthritis</kwd><kwd>sensitivity of symptoms</kwd><kwd>enthesitis</kwd><kwd>dactylitis</kwd><kwd>psoriatic arthritis</kwd><kwd>psoriatic spondylitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Агабабова ЭР, Бадокин ВВ, Эрдес ШФ и др. Разработка и апробация диагностических критериев псориатического артрита. Терапевтический архив. 1998;12:117-21 [Agababova ER, Badokin VV, Erdes ShF, et al. 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