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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2017-1-19-22</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-733</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Распространенность псориатического артрита и коморбидных заболеваний у больных тяжелым псориазом: данные ретроспективного анализа госпитальной когорты</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of psoriatic arthritis and comorbidities in patients with severe psoriasis: Data of a retrospective analysis of a hospital cohort</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баткаева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Batkaeva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Факультет повышения квалификации медицинских работников</p><p>117198, Москва, ул. Миклухо-Маклая, 21, корп. 3</p></bio><bio xml:lang="en"><p>Faculty for Advanced Training of Medical Workers</p><p>21, Miklukho-Maklai St., Build. 3, Moscow 117198</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коротаева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotaeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><email xlink:type="simple">tatianakorotaeva@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баткаев</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Batkaev</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Факультет повышения квалификации медицинских работников</p><p>117198, Москва, ул. Миклухо-Маклая, 21, корп. 3</p></bio><bio xml:lang="en"><p>Faculty for Advanced Training of Medical Workers</p><p>21, Miklukho-Maklai St., Build. 3, Moscow 117198</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>RUDN University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>24</day><month>03</month><year>2017</year></pub-date><volume>11</volume><issue>1</issue><fpage>19</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баткаева Н.В., Коротаева Т.В., Баткаев Э.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Баткаева Н.В., Коротаева Т.В., Баткаев Э.А.</copyright-holder><copyright-holder xml:lang="en">Batkaeva N.V., Korotaeva T.V., Batkaev E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/733">https://mrj.ima-press.net/mrj/article/view/733</self-uri><abstract><p>Цель исследования – изучить распространенность псориатического артрита (ПсА) и коморбидных заболеваний у госпитальной когорты больных с тяжелым псориазом (Пс).</p><sec><title>Пациенты и методы</title><p>Пациенты и методы. Выполнен ретроспективный анализ данных историй болезней 592 больных Пс (348 мужчин и 244 женщин, средний возраст – 49,2±0,6 года, средняя длительность Пс – 11,8±0,6 года, средний PASI – 49,4±0,5 балла), находившихся на стационарном лечении в филиале «Клиника им. В.Г. Короленко» Московского научно-практического центра дерматовенерологии и косметологии с 2010 по 2011 г. Диагноз сопутствующих заболеваний подтверждали врачи-специалисты в соответствии с кодом по МКБ-10; анализировали частоту и структуру (в %) коморбидных заболеваний.</p></sec><sec><title>Результаты</title><p>Результаты. У 503 (85,1%) из 592 больных Пс выявлены сопутствующие заболевания. У большинства пациентов (61,6%) зарегистрированы сердечно-сосудистые заболевания (ССЗ; I00–I199). ПсА выявлен у 39,4% обследованных (L40.5, M07.0–M07.3). Другие заболевания костно-мышечной системы, не связанные с псориазом (M00–M99), имелись у 27,6% пациентов. Заболевания желудочно-кишечного тракта (ЖКТ) и гепатобилиарной системы (К00–К93, В15–В19) выявлены у 47,5% больных. Заболевания эндокринной системы, расстройства питания, нарушения обмена веществ (Е00–Е90), в частности сахарный диабет, болезни щитовидной железы, ожирение, диагностированы соответственно у 12,2, 24 и 88% больных Пс. Заболевания мочеполового тракта имелись у 13,9% пациентов с Пс, из них хронический пиелонефрит (N20), кисты почек (N28.1), мочекаменная болезнь (Q61), заболевания предстательной железы (N11) отмечены в 73; 71; 47 и 27% случаев соответственно.</p></sec><sec><title>Выводы</title><p>Выводы. У большинства пациентов с тяжелым Пс наблюдается коморбидная патология, в первую очередь заболевания опорно-двигательного аппарата, ССЗ и ЖКТ. ПсА зарегистрирован более чем у трети больных. У 36% больных Пс выявлена коморбидная патология.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to study the prevalence of psoriatic arthritis (PsA) and comorbidities in a hospital cohort of patients with severe psoriasis (PsO).</p></sec><sec><title>Patients and methods</title><p>Patients and methods. Case history data were retrospectively analyzed in 592 patients with PsO (348 men and 244 women; mean age, 49.2±0.6 years; mean PsO duration, 11.8±0.6 years; mean Psoriasis Area and Severity Index (PASI), 49.4±0.5 scores) who had been treated at the Branch of the V.G. Korolenko Clinic, Moscow Research and Practical Center of Dermatovenereology and Cosmetology, in 2010 to 2011. The diagnosis of comorbidities was confirmed by medical specialists in accordance with the ICD-10 code; the rate and pattern (%) of comorbidities were analyzed.</p></sec><sec><title>Results</title><p>Results. Out of the 592 patients with PsO, 503 (85.1%) were found to have comorbidities. Diseases of the cardiovascular system (CVS)(I00–I199) were recorded in the majority (61.6%) of the patients. PsA (L40.5, M07.0–M07.3) was detected in 39.4% of the examinees. Other diseases of the skeletomuscular system unassociated with psoriasis (M00–M99) were present in 27.6% of the patients. Diseases of the gastrointestinal tract (GIT) and hepatobiliary system (K00–K93, B15–B19) were found in 47.5% of the patients. Endocrine diseases, nutritional and metabolic disorders (E00–E90), particularly diabetes mellitus, thyroid diseases, and obesity, were diagnosed in 12.2, 24, and 88% of the patients with PsO, respectively. 13.9% of the patients with PsO had urinary tract diseases, among them there was chronic pyelonephritis (N20), kidney cysts (N28.1), urolithiasis (Q61), prostate diseases (N11) in 73, 71, 47, and 27% of cases, respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Most patients with severe PsO were observed to have comorbidity, primarily diseases of the locomotor apparatus, CVS, and GIT. PsA was recorded in more than one third of patients. Comorbidity was identified in 36% of the patients with PsO.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>псориатический артрит</kwd><kwd>коморбидная патология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>psoriatic arthritis</kwd><kwd>comorbidity.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yeung H, Takeshita J, Mehta NN, et al. Psoriasis severity and the prevalence of major medical comorbidity: a population-based study. JAMA Dermatol. 2013 Oct;149(10):1173-9. doi: 10.1001/jamadermatol.2013.5015.</mixed-citation><mixed-citation xml:lang="en">Yeung H, Takeshita J, Mehta NN, et al. 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