mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2017-1-62-65mrj-740Research ArticleОБЗОРЫREVIEWSПрименение высокомолекулярных препаратов гиалуроновой кислоты в терапии остеоартритаThe use of highmolecular-weight hyaluronic acid in the treatment of osteoarthritisАникинС. Г.AnikinS. G.

115522, Москва, Каширское шоссе, 34А

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artos2000@yandex.ruФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation2017240320171116265Copyright © Аникин С.Г., 20172017Аникин С.Г.Anikin S.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/740

Остеоартрит (ОА) является одним из самых распространенных заболеваний скелетно-мышечной системы, поражающих преимущественно лиц старших возрастных групп. Для лечения ОА применяют комбинированную терапию с использованием фармакологических и нефармакологических методов, включая препараты гиалуроновой кислоты. Гиланы представляют собой высокомолекулярные (ВМ) производные гиалуроновой кислоты (ГНК). Применение гиланов сопровождается уменьшением боли, скованности и улучшением функциональной активности. Их эффективность сопоставима с таковой низкомолекулярных препаратов ГНК. Внутрисуставное введение ВМ производных ГНК является безопасным и эффективным методом лечения ОА.

Osteoarthritis (OA) is one of the most common diseases of the musculoskeletal system, affecting mainly people of old age. The management of OA requires combined therapy using pharmaceutical and nonpharmacological modalities, including hyaluronic acid (HA). Hylans are highmolecular-weight (HMW) HA derivatives. The use of hylans results in reducing pain and stiffness and in improving functional activity. Their efficacy is comparable with that of lowmolecular-weight HA. Intraarticular injection of HMW HA derivatives is safe and effective for treating OA.

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The authors declare that there are no conflicts of interest present.