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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2018-2-4-11</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-820</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group></article-categories><title-group><article-title>Лихорадка неясного происхождения в ревматологии</article-title><trans-title-group xml:lang="en"><trans-title>Fever of unknown origin in rheumatology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гордеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gordeev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><email xlink:type="simple">avg1305@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савушкина</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Savushkina</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галушко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Galushko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А.  Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>06</day><month>06</month><year>2018</year></pub-date><volume>12</volume><issue>2</issue><fpage>4</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гордеев А.В., Савушкина Н.М., Галушко Е.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Гордеев А.В., Савушкина Н.М., Галушко Е.А.</copyright-holder><copyright-holder xml:lang="en">Gordeev A.V., Savushkina N.M., Galushko E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/820">https://mrj.ima-press.net/mrj/article/view/820</self-uri><abstract><p>В статье рассмотрено современное состояние проблемы лихорадки неясного происхождения (ЛНП). Освещены основные этапы изучения данного вопроса с подробным описанием происходивших со временем изменений классификационных диагностических критериев, этиологических вариантов и клинических признаков отдельных видов ЛНП. Представлен дифференциально-диагностический алгоритм ведения больных ЛНП, проанализирована диагностическая ценность наиболее значимых лабораторных и инструментальных методов обследования. Описан РРР-синдром как один из возможных этиологических факторов ЛНП. Обозначен круг наиболее частых причин развития ЛНП у пациентов разного возраста. Отмечено, что наиболее частой причиной ЛНП у пожилых больных являются ревматические заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The article considers the current state of the problem related to fever of unknown origin (FUO). It highlights the main stages of studying this issue with a detailed description of the classification diagnostic criteria, etiological types, and clinical signs of certain types of FUO, which have undergone changes over time. The authors present a differential diagnostic algorithm for managing patients with FUO and analyze the diagnostic value of the most significant laboratory and instrumental studies. PPP-syndrome is described as one of the possible etiological factors for FUO. The circle of the most common of FUO is denoted in patients at different ages. It is noted that rheumatic diseases are the most common cause of FUO in elderly patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лихорадка неясного происхождения</kwd><kwd>ревматические заболевания</kwd><kwd>гипертермия</kwd><kwd>неинфекционные воспалительные заболевания</kwd><kwd>позитронно-эмиссионная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>fever of unknown origin</kwd><kwd>rheumatic diseases</kwd><kwd>hyperthermia</kwd><kwd>non-infectious inflammatory diseases</kwd><kwd>positron emission tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Durack DT, Street AC. Fever of unknown origin-re-examined and redefined. Curr Clin Top Infect Dis. 1991;11:35-51.</mixed-citation><mixed-citation xml:lang="en">Durack DT, Street AC. Fever of unknown origin-re-examined and redefined. 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