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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2018-3-4-18</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-838</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GUIDELINES</subject></subj-group></article-categories><title-group><article-title>Проект междисциплинарных рекомендаций по диагностике, методам оценки степени активности, терапевтической эффективности и применению генно-инженерных биологических препаратов у пациентов с сочетанными иммуновоспалительными заболеваниями (псориаз, псориатический артрит, болезнь Крона)</article-title><trans-title-group xml:lang="en"><trans-title>Draft interdisciplinary guidelines for diagnosis, methods for estimation of the degree of activity, for evaluation of therapeutic efficacy, and for use of biological agents in patients with concomitant immunoinflammatory diseases (psoriasis, psoriatic arthritis, Crohn's disease)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдулганиева</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdulganieva</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420012, Республика Татарстан, Казань, ул. Бутлерова, 49</p></bio><bio xml:lang="en"><p>49, Butlerov St., Kazan, Republic of Tatarstan 420012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакулев</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakulev</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Belousova</surname><given-names>E. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Александровна Белоусова</p><p>129110, Москва, ул. Щепкина, 61/2</p></bio><bio xml:lang="en"><p>Elena Aleksandrovna Belousova</p><p>61/2, Shchepkin St., Moscow 129110</p></bio><email xlink:type="simple">eabelous@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Знаменская</surname><given-names>Л. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Znamenskaya</surname><given-names>L. F.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коротаева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotaeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Викторовна Коротаева</p><p>115522, Москва, Каширское шоссе, 34А </p></bio><bio xml:lang="en"><p>Tatiana Viktorovna Korotaeva</p><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><email xlink:type="simple">tatianakorotaeva@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Круглова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglova</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кохан</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokhan</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайрутдинов</surname><given-names>В. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khairutdinov</surname><given-names>V. R.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халиф</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Khalif</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хобейш</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khobeish</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марианна Михайловна Хобейш</p><p>197022, Санкт-Петербург, ул. Льва Толстого, 6-8</p></bio><bio xml:lang="en"><p>Marianna Mikhailovna Khobeish</p><p>6-8, Lev Tolstoy St., Saint Petersburg 197022 </p></bio><email xlink:type="simple">mkhobeysh@yandex.ru</email><xref ref-type="aff" rid="aff-10"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Саратовский государственный медицинский университет им. В.И. Разумовского» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.F. Vladimirsky Moscow Regional Research and Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБУ «Государственный научный центр дермато-венерологии и косметологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Research Center for Dermatovenereology and Cosmetology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy, Presidential Administration of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>ГБУ Свердловской области «Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Research Institute of Dermatovenerology and Immunopathology, Yekaterinburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>ФГБОУ ВО «Военно-медицинская академия им. С.М. Кирова» Министерства обороны России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.M. Kirov Military Medical Academy, Ministry of Defense of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>ФГБУ «Государственный научный центр колопроктоло гии им. А.Н. Рыжих» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.N. Ryzhikh State Research Center for Coloproctology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>15</day><month>09</month><year>2018</year></pub-date><volume>12</volume><issue>3</issue><fpage>4</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абдулганиева Д.И., Бакулев А.Л., Белоусова Е.А., Знаменская Л.Ф., Коротаева Т.В., Круглова Л.С., Кохан М.М., Лила А.М., Хайрутдинов В.Р., Халиф И.Л., Хобейш М.М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Абдулганиева Д.И., Бакулев А.Л., Белоусова Е.А., Знаменская Л.Ф., Коротаева Т.В., Круглова Л.С., Кохан М.М., Лила А.М., Хайрутдинов В.Р., Халиф И.Л., Хобейш М.М.</copyright-holder><copyright-holder xml:lang="en">Abdulganieva D.I., Bakulev A.L., Belousova E.А., Znamenskaya L.F., Korotaeva T.V., Kruglova L.S., Kokhan M.M., Lila A.M., Khairutdinov V.R., Khalif I.L., Khobeish M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/838">https://mrj.ima-press.net/mrj/article/view/838</self-uri><abstract><p>В связи с высоким риском развития у одного пациента нескольких иммунновоспалительных заболеваний (псориаз, псориатический артрит – ПсА и болезнь Крона – БК) крайне актуальными являются их ранняя диагностика и адекватная терапия. Междисциплинарной рабочей группой, в которую вошли эксперты ревматологи, гастроэнтерологи и дерматологи, разработан проект рекомендаций по ранней диагностике, методам оценки активности и показаниям к применению генно-инженерных биологических препаратов у пациентов с сочетанной иммуновоспалительной патологией – псориазом, ПсА, БК. В соответствии с решением Совета экспертов и результатами обсуждения со специалистами из разных регионов Российской Федерации будут предприняты дальнейшие шаги для валидации рекомендаций.</p></abstract><trans-abstract xml:lang="en"><p>Due to that one patient may be at high risk for developing several immunoinflammatory diseases (psoriasis, psoriatic arthritis (PsA), and Crohn's disease (CD)), their early diagnosis and adequate therapy are extremely relevant. The Interdisciplinary Working Group that includes experts in rheumatology, gastroenterology and dermatology has developed draft guidelines for early diagnosis, methods for activity assessments and for indications for the use of biological agents in patients with concomitant immunoinflammatory diseases (psoriasis, PsA, and CD). In accordance with the decision adopted by the Council of Experts and with the results of a discussion with experts from different regions of the Russian Federation, further steps will be undertaken to validate the guidelines.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>междисциплинарные рекомендации</kwd><kwd>псориаз</kwd><kwd>псориатический артрит</kwd><kwd>болезнь Крона</kwd></kwd-group><kwd-group xml:lang="en"><kwd>interdisciplinary guidelines</kwd><kwd>psoriasis</kwd><kwd>psoriatic arthritis</kwd><kwd>Crohn's disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kavanaugh A, Helliwell P, Ritchlin C. Psoriatic arthritis and burden of disease: patient perspectives from the population-based multinational assessment of psoriasis and psoriatic arthritis (MAPP) survey. Rheumatol Ther. 2016 Jun;3(1):91-102. doi: 10.1007/s40744-016-0029-z. 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