mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2018-3-19-28mrj-839Research ArticleОБЗОРЫREVIEWSАнкилозирующий спондилит и беременность : современный взгляд на проблемуAnkylosing spondylitis and pregnancy: a current view on the problemКричевскаяО. А.KrichevskayaO. A.

Ольга Аркадьевна Кричевская

115522, Москва, Каширское шоссе, 34А

Olga Arkadyevna Krichevskaya

34A, Kashirskoe Shosse, Moscow 115522

o.krichevskaya@mail.ruГандалоеваЗ. М.GandaloevaZ. M.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ДубининаТ. В.DubininaТ. V.

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation2018150920181231928Copyright © Кричевская О.А., Гандалоева З.М., Дубинина Т.В., 20182018Кричевская О.А., Гандалоева З.М., Дубинина Т.В.Krichevskaya O.A., Gandaloeva Z.M., Dubinina Т.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/839

Анкилозирующий спондилит (АС) чаще развивается в 3–4-м десятилетии жизни, когда многие женщины задумываются о материнстве. Сегодня пересмотрено господствовавшее с середины XX в. мнение об АС как о мужской болезни: соотношение мужчин и женщин, страдающих этим заболеванием, приближается к 1 : 1, что обусловливает актуальность изучения проблемы беременности при АС. В обзоре приведены данные литературы о фертильности при АС, взаимовлиянии АС и беременности, лекарственной терапии при гестации. Обосновано проведение дальнейших исследований, направленных на уточнение течения АС, оптимизацию оценки его активности и функционального состояния больных, выявление маркеров обострения заболевания во время беременности и после родов, стандартизацию лекарственной терапии как на этапе подготовки к беременности, так и на ее фоне.

Ankylosing spondylitis (AS) more often develops in the 3rd and 4th decade of life when many women think about motherhood. Today, the view which has prevailed since the middle of the 20th century on AS as a male disease has been revised; the male to female ratio for this disease is approaching 1:1, which makes it urgent to study the problem of pregnancy in AS. The review gives the data available in the literature on fertility in AS, the interaction of the latter and pregnancy, and drug therapy during gestation. There is evidence for further investigations to clarify the course of AS, to optimize the assessment of its activity and patients' functional status, to identify markers for an exacerbation of the disease during pregnancy and after childbirth, and to standardize drug therapy when preparing for pregnancy and during the latter.

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The authors declare that there are no conflicts of interest present.