mrjСовременная ревматологияModern Rheumatology Journal1996-70122310-158XIMA-PRESS, LLC10.14412/1996-7012-2018-3-34-39mrj-840Research ArticleОБЗОРЫREVIEWSСовременные возможности ранней диагностики системной красной волчанкиCurrent possibilities for early diagnosis of systemic lupus erythematosusЛилаВ. А.LilaV. A.

Виктория Александровна Лила

191015, Санкт-Петербург, ул. Кирочная, 41

Viktoria Aleksandrovna Lila

41, Kirochnaya St., Saint Petersburg 191015

liu_lo@mail.ruМазуровВ. И.MazurovV. I.ЛапинС. В.LapinS. V.МазингА. В.MazingA. V.МошниковаА. Н.MoshnikovaA. N.ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава РоссииРоссияI.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaRussian FederationФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова» Минздрава РоссииРоссияAcad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of RussiaRussian Federation2018150920181233439Copyright © Лила В.А., Мазуров В.И., Лапин С.В., Мазинг А.В., Мошникова А.Н., 20182018Лила В.А., Мазуров В.И., Лапин С.В., Мазинг А.В., Мошникова А.Н.Lila V.A., Mazurov V.I., Lapin S.V., Mazing A.V., Moshnikova A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mrj.ima-press.net/mrj/article/view/840

В обзоре представлены данные литературы о применении теста волчаночной полоски при системной красной волчанке (СКВ). Тест волчаночной полоски (ТВП) – метод прямой иммунофлюоресценции, используемый для обнаружения иммуноглобулинов и факторов комплемента в дермоэпидермальном соединении биоптатов кожи. ТВП может быть использован в качестве одного из диагностических тестов для ранней диагностики СКВ у пациентов без кожных проявлений, а также при «неполной» СКВ. Как и показатели других лабораторных исследований, результаты ТВП могут учитываться при установлении окончательного диагноза только в совокупности с другими клиническими, иммунологическими и инструментальными данными.

The review presents the data available in the literature on the use of the lupus band test (LBT) for systemic lupus erythematosus (SLE). LBT is a direct immunofluorescence method used to detect immunoglobulins and complement factors in the dermoepidermal junction of skin biopsy specimens. LBT may be applied as one of the diagnostic tests for early diagnosis of SLE in patients without skin manifestations and in those of incomplete SLE. Like the results of other laboratory tests, those of LBT may be taken into account when establishing a final diagnosis only in conjunction with other clinical, immunological and instrumental data.

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The authors declare that there are no conflicts of interest present.