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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mrj</journal-id><journal-title-group><journal-title xml:lang="ru">Современная ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Modern Rheumatology Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1996-7012</issn><issn pub-type="epub">2310-158X</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1996-7012-2019-2-9-21</article-id><article-id custom-type="elpub" pub-id-type="custom">mrj-905</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURES</subject></subj-group></article-categories><title-group><article-title>Остеоартрит: эпидемиология, классификация, факторы риска и прогрессирования, клиника, диагностика, лечение</article-title><trans-title-group xml:lang="en"><trans-title>Osteoarthritis: epidemiology, classification, risk factors, and progression, clinical presentation, diagnosis, and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoye Shosse, Moscow 115522</p></bio><email xlink:type="simple">dr.alekseeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таскина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Taskina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoye Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашеварова</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashevarova</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoye Shosse, Moscow 115522</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>13</day><month>05</month><year>2019</year></pub-date><volume>13</volume><issue>2</issue><fpage>9</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева Л.И., Таскина Е.А., Кашеварова Н.Г., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Алексеева Л.И., Таскина Е.А., Кашеварова Н.Г.</copyright-holder><copyright-holder xml:lang="en">Alekseeva L.I., Taskina E.A., Kashevarova N.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://mrj.ima-press.net/mrj/article/view/905">https://mrj.ima-press.net/mrj/article/view/905</self-uri><abstract><p>В статье впервые подробно представлена распространенность остеоартрита (ОА), рассмотрены предикторы развития и прогрессирования заболевания. Описаны клиническая классификация ОА и его место в МКБ-10. Детально охарактеризована клиническая картина заболевания в зависимости от локализации процесса. Отмечено изменение представлений об ОА как о классической модели ноцицептивной боли. Приведены клинические и лабораторно-инструментальные методы диагностики заболевания и классификационные и диагностические критерии, большое внимание уделено современным принципам терапии ОА, согласно российским клиническим рекомендациям, рекомендациям Европейского общества по клиническим и экономическим аспектам остеопороза и остеоартрита (European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, ESCEO) и Европейской лиги против ревматизма (European League Against Rheumatism, EULAR).</p></abstract><trans-abstract xml:lang="en"><p>For the first time, the paper presents in detail the prevalence of osteoarthritis (OA) and considers the predictors of disease development and progression. The clinical classification of OA and its place in the ICD-10 are described. The clinical presentation of the disease is characterized in detail according to the localization of the process. It is noted that there is a change in the understanding of OA as a classic model of nociceptive pain. The paper depicts clinical, laboratory, and instrumental methods for diagnosing the disease, as well as classification and diagnostic criteria; much attention is paid to the current principles of OA therapy according to the Russian clinical recommendations and the guidelines of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the European League Against Rheumatism (EULAR).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>остеоартрит</kwd><kwd>эпидемиология</kwd><kwd>классификация</kwd><kwd>факторы риска</kwd><kwd>клиника</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteoarthritis</kwd><kwd>epidemiology</kwd><kwd>classification</kwd><kwd>risk factors</kwd><kwd>clinical presentation</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cunningham LS, Kelsey JL. 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