THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS
https://doi.org/10.14412/1996-7012-2016-4-64-68
Abstract
The paper analyzes two matching-adjusted indirect comparison-based investigations of the efficacy of adalimumab (ADA) and secukinumab (SCM) in active ankylosing spondylitis, which have been recently reported at the EULAR Congress (London, 2016). One study sponsored by AbbVie was conducted to determine the short-term (16-week) comparative clinical and economic efficacy of the test drugs and the other was supported by Novartis to reveal long-term (52-week), only clinical efficacy. Both studies have shown that the short-term efficacy ofADAand SCM is practically similar; however, the latter has a better long-term clinical efficacy. A pharmacoeconomic analysis of both drugs used during the first 12 weeks has demonstrated some advantage ofADA.
About the Author
Sh. F. Erdes
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
Contact: Shandor Fedorovich Erdes; V.A. Nasonova Research Institute of Rheumatology, 34A, Kashirskoe Shosse,Moscow115552
References
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Review
For citations:
Erdes SF. THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2016;10(4):64-68. (In Russ.) https://doi.org/10.14412/1996-7012-2016-4-64-68
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