Forecasting index of unfavorable outcomes of systemic lupus erythematosus
E. A. Aseeva,
N. Yu. Nikishina,
A. A. Mesnyankina,
S. K. Solovyev,
B. Sh. Isaeva,
G. M. Koilubaeva,
A. M. Lila https://doi.org/10.14412/1996-7012-2021-3-98-102
Abstract
The development of irreversible organ damage (IOD) in systemic lupus erythematosus (SLE) significantly increases the risk of death, worsens the quality of life and significantly increases the cost of treatment. The development and implementation of specific tools that will promote early identification of the risk of unfavorable outcomes is a priority. The article presents literature review on a new method for prediction of unfavorable outcomes in SLE – frailty index (FI, vulnerability index). FI, developed by a group of international experts on the basis of the database of the international cohort of SLE patients – SLICC (Systemic Lupus International Collaborating Clinics) – is easily reproducible in real clinical practice and can be used in patients with an early stage of SLE to predict the risk of death, the development of IOD. and hospitalization. The SLE Forecasting index of unfavorable outcomes (SLICC-FI) appears to be a promising clinical and research tool for identifying those who need more careful monitoring and an individual therapeutic strategy at an early stage of the disease.
About the Authors
E. A. Aseeva
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
Elena Alexandrovna Aseeva
34A, Kashirskoe Shosse, Moscow 115522, Russia
N. Yu. Nikishina
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522, Russia
A. A. Mesnyankina
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522, Russia
S. K. Solovyev
JSC Group of companies MEDSI
Russian Federation
Russian Federation
3A, Gruzinskiy pereulok, Moscow 123056, Russia
B. Sh. Isaeva
Asfendiyarov Kazakh National Medical University
Kazakhstan
Kazakhstan
94, Tole Bi Street, Almaty 050000, Kazakhstan
G. M. Koilubaeva
Academician M. Mirrakhimov National Center for Cardiology and Therapy
Kyrgyzstan
Kyrgyzstan
3, Togolok Moldo St., Bishkek 720040, Kyrgyzstan
A. M. Lila
V.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522, Russia
2/1, Barrikadnaya St., Build. 1, Moscow 125993, Russia
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Review
For citations:
Aseeva EA, Nikishina NY, Mesnyankina AA, Solovyev SK, Isaeva BS, Koilubaeva GM, Lila AM. Forecasting index of unfavorable outcomes of systemic lupus erythematosus. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2021;15(3):98-102. (In Russ.) https://doi.org/10.14412/1996-7012-2021-3-98-102
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