Clinical significance of antibodies to the phosphatidylserine/prothrombin complex
https://doi.org/10.14412/1996-7012-2022-2-81-86
Abstract
Classical serological markers of antiphospholipid syndrome (APS) are antibodies to cardiolipin, antibodies to β2-glycoprotein 1, and lupus anticoagulant. The utility of testing other antiphospholipid antibodies, not included in the classification criteria for improving the diagnosis of autoimmune thrombophilia continues to be debated. The review presents literature data on the study of antibodies to prothrombin and the phosphatidylserine/prothrombin complex in patients with systemic lupus erythematosus and APS.
About the Authors
T. M. Reshetnyak
V.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Tatyana Magomedalievna Reshetnyak
34A, Kashirskoe shosse, Moscow 115522, Russia
2/1, Barrikadnaya street, building 1, Moscow 125993, Russia
F. A. Cheldieva
V.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
34A, Kashirskoe shosse, Moscow 115522, Russia
2/1, Barrikadnaya street, building 1, Moscow 125993, Russia
M. V. Cherkasova
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe shosse, Moscow 115522, Russia
A. M. Lila
V.A. Nasonova Research Institute of Rheumatology; Department of Rheumatology, Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
34A, Kashirskoe shosse, Moscow 115522, Russia
2/1, Barrikadnaya street, building 1, Moscow 125993, Russia
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Review
For citations:
Reshetnyak TM, Cheldieva FA, Cherkasova MV, Lila AM. Clinical significance of antibodies to the phosphatidylserine/prothrombin complex. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2022;16(2):81-86. (In Russ.) https://doi.org/10.14412/1996-7012-2022-2-81-86
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