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Бисфосфонаты: приверженность терапии - залог успешного лечения остеопороза

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1. <div><p>Клинические рекомендации «Остеопороз. Диагностика, профилактика и лечение» (ред. Л.И. Беневоленская, О.М. Лесняк). М.: ГЭОТАР-Медиа, 2005, 171 с.</p><p>Hochberg M.C., Greenspan S., Wasnich R.D. Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agents. J Clin Endocrinol Metab 2002; 87, 1586-92.</p><p>Беневоленская Л.И. Бисфосфонаты в терапии и профилактике остеопороза. Рос pевматол 1998; 2: 2-9.</p><p>Fleisch H. Bisphosphonates: mechanisms of action. Endocr Rev 1998; 19:80-100.</p><p>Rogers M.J. New insights into the molecular mechanisms of action of bisphosphonates. Curr Pharm Des 2003; 9: 2643-58.</p><p>World Health Organization. Adherence to long-term therapies: evidence for action. Geneva: WHO, 2003.</p><p>Baroutsou B., Babiolakis D., Stamatiadou A. et al. Patient compliance and preference of alendronate once weekly administration in comparison with daily regimens for osteoporotic postmenopausal women. Ann Rheum Dis 2004; 63(suppl. 1): 455(SATO240).</p><p>Kendler D., Kung A.W., Fuleihan Gel H. et al. Patients with osteoporosis prefer once weekly to once daily dosing with alendronate. Maturitas 2004; 48: 243-51.</p><p>Simon J.A., Lewiecki E.M., Smith M.E. et al. Patient preference for once-weekly alendronate 70 mg versus once-daily alendronate 10 mg: a multicenter, randomized, open-label, cross-over study. Clin Ther 2002; 24: 1871-86.</p><p>Cramer J., Amonkar M.M., Hebborn A. et al. Compliance and persistence with bisphosphonate dosing regimens among women with post- menopausal osteoporosis. Curr Med Res Opin 2005; 21: 1453-60.</p><p>Emkey R., Koltun W., Beusterien K. et al. Patient preference for once-monthly ibandronate versus once-weekly alendronate in a randomized, open-label, cross-over trial: the Bonviva Alendronate Trial in Osteoporosis. Curr Med Res Opin 2005; 21: 1895-903.</p><p>Barrett J., Worth E., Bauss F., Epstein S. Ibandronate: a clinical pharmacological and pharma-cokinetic update. J Clin Pharmacol 2004; 44: 951-65.</p><p>Bauss F., Russel R.G. Ibandronate in osteoporosis: preclinical data and rationale for intermittent dosing. Osteoporosis Int 2004; 15: 423-33.</p><p>Munbauers R.C., Bauss F., Schenk R. et al. Ibandronate, a potent new bisphosphonate to inhibit bone resorption. J Bone Miner Res 1991; 6: 1003-11.</p><p>Bauss F., Wagner M., Hothorn L.H. Total administered dose of ibandronate determines its effects on bone mass and architecture in ovariec- tomized aged rats. J Rheumatol 2002; 29: 990-98.</p><p>Bidstrup B., Ise J., Huss H. et al. Total dose, and not dosing frequency, determines treatment response to ibandronate. Osteoporos Int 2000; 11(suppl.1): S26.</p><p>Fleisch H. The bisphosphonate ibandronate, given daily as well as discontinuously, decreases bone resorption and increases calcium retention as assessed by 45Ca kinetics in the intact rat. Osteoporos Int 1996; 6: 166-70.</p><p>Monier-Faugere M.C., Geng Z., Paschalis E.P. et al. Intermittent and continuous administration of the bisphosphonate ibandronate in ovariectomized beagle dogs: effects on bone morthometry and mineral properties. J Bone Miner Res 1999; 14: 1768-78.</p><p>Cooper C., Emkey R.D., McDonald R.H. et al. Efficacy and safety of oral weekly iban-dronate in the treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab 2003; V 88: P 4609 - 15.</p><p>Riis B.J., Ise J., von Stein T. et al. Ibandronate: A comparison of oral daily dosing versus intermittent dosing in postmenopausal osteoporosis. J Bone Miner Res 2001; 16: 1871-8.</p><p>Reginster J.-Y., Wilson K.M., Dumount E. 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Для цитирования:

Торопцова Н.В., Беневоленмкая Л.И., Торопцова Н.В., Беневоленмкая Л.И. Бисфосфонаты: приверженность терапии - залог успешного лечения остеопороза. Современная ревматология. 2008;2(1):78-81.

For citation:

Toroptsova N.V., Benevolenskaya L.I., Toroptsova N.V., Benevolenskaya L.I. Biophosphonates: adherence to therapy is a pledge of successful treatment for osteoporosis. Modern Rheumatology Journal. 2008;2(1):78-81. (In Russ.)

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