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Assessment of the feasibility of using a preparation containing a combination of B vitamins (B1 – thiamine, B6 – pyridoxine, and B12 – cyanocobalamin) in the multimodal treatment of pain in osteoarthritis: expert council resolution

https://doi.org/10.14412/1996-7012-2025-4-111-116

Abstract

The expert council evaluated the appropriateness of using a preparation containing a combination of B-group vitamins in the multimodal treatment of pain associated with osteoarthritis (OA). Theoretical rationale, clinical trial data, and meta-analyses support the consideration of high-dose B vitamin complexes as an effective component of combination therapy for musculoskeletal pain in OA.

About the Authors

A. M. Lila
V.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of the Russia
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522;

2/1, Barrikadnaya Street, Build. 1, Moscow 125993


V. I. Mazurov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

41, Kirochnaya Street, St. Petersburg 191015


L. I. Alexeeva
V.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional Education, Ministry of Health of the Russia
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522;

2/1, Barrikadnaya Street, Build. 1, Moscow 125993


A. V. Amelin
Pavlov First Saint Petersburg State Medical University
Russian Federation

6–8, Lev Tolstoy Street, St. Petersburg 197022


I. F. Akhtyamov
Kazan State Medical University; Republican Clinical Hospital, Ministry of Health of the Republic of Tatarstan
Russian Federation

49, Butlerova Street, Kazan 420012;

138, Orenburgsky Trakt, Kazan 420064


V. A. Badtieva
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); S.I. Spasokukotsky Center for Medical Rehabilitation and Sports Medicine
Russian Federation

8, Trubetskaya Street, Build. 2, Moscow 119048;

53, Zemlyanoy Val Street, Build. 1, Moscow 105120


E. I. Bialik
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522


O. M. Drapkina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

10, Petrovyerigsky Lane, Build. 3, Moscow 101000


E. V. Ekusheva
Federal Scientific and Clinical Center of Specialized Medical Care and Medical Technologies
Russian Federation

28, Orekhovy Boulevard, Moscow 115682


N. V. Zagorodny
N.N. Priorov National Medical Research Center of Traumatology and Orthopedics; RUDN University
Russian Federation

10, Priorova Street, Moscow 127299;

6, Miklukho-Maklaya Street, Moscow 117198


A. I. Zagrebneva
North-Western State Medical University named after I.I. Mechnikov; Moscow Clinical Research Center, Hospital №.52
Russian Federation

41, Kirochnaya Street, St. Petersburg 191015;

3, Pekhotnaya Street, Moscow 123182


E. V. Zonova
Novosibirsk State Medical University
Russian Federation

52, Krasny Prospekt, Novosibirsk 630091


D. A. Iskra
St. Petersburg State Pediatric Medical University
Russian Federation

152, Litovskaya Street, St. Petersburg 194100


A. E. Karateev
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522


D. E. Karateev
M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

61/2, Shchepkina Street, Moscow 129110


A. A. Klimenko
Institute of Clinical Medicine, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia (Pirogov University)
Russian Federation

1, Ostrovityanova Street, Moscow 117513


N. N. Kornilov
R.R. Vreden National Medical Research Center of Traumatology and Orthopedics
Russian Federation

8, Akademika Baikova Street, St. Petersburg 195427


S. A. Lapshina
Kazan State Medical University
Russian Federation

49, Butlerova Street, Kazan 420012


V. A. Lila
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

41, Kirochnaya Street, St. Petersburg 191015


M. A. Makarov
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522


A. V. Naumov
Russian Gerontological Scientific and Clinical Center, N.I. Pirogov Russian National Research Medical University Ministry of Health of Russia (Pirogov University)
Russian Federation

16, 1st Leonova Street, Moscow 129226


E. N. Otteva
Institute for Advanced Training of Healthcare Specialists of the Ministry of Health of the Khabarovsk Territory; Regional Clinical Hospital №1 named after Prof. S.I. Sergeev
Russian Federation

9, Krasnodarskaya Street, Khabarovsk 680009


V. A. Parfenov
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation

8, Trubetskaya draStreet, Build. 2, Moscow 119048


E. A. Taskina
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522


A. N. Torgashin
N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Russian Federation

10, Priorova Street, Moscow 127299


E. A. Trofimov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

41, Kirochnaya Street, St. Petersburg 191015


P. A. Shesternya
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky, Ministry of Health of Russia
Russian Federation

1, Partizana Zheleznyaka Street, Krasnoyarsk 660022


E. S. Filatova
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

34A, Kashirskoye Shosse, Moscow 115522


S. P. Yakupova
Kazan State Medical University
Russian Federation

49, Butlerova Street, Kazan 420012


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Review

For citations:

Lila AM, Mazurov VI, Alexeeva LI, Amelin AV, Akhtyamov IF, Badtieva VA, Bialik EI, Drapkina OM, Ekusheva EV, Zagorodny NV, Zagrebneva AI, Zonova EV, Iskra DA, Karateev AE, Karateev DE, Klimenko AA, Kornilov NN, Lapshina SA, Lila VA, Makarov MA, Naumov AV, Otteva EN, Parfenov VA, Taskina EA, Torgashin AN, Trofimov EA, Shesternya PA, Filatova ES, Yakupova SP. Assessment of the feasibility of using a preparation containing a combination of B vitamins (B1 – thiamine, B6 – pyridoxine, and B12 – cyanocobalamin) in the multimodal treatment of pain in osteoarthritis: expert council resolution. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2025;19(4):111-116. (In Russ.) https://doi.org/10.14412/1996-7012-2025-4-111-116

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ISSN 1996-7012 (Print)
ISSN 2310-158X (Online)

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