Current concepts of erythema nodosum: from etiology to management strategy
https://doi.org/10.14412/1996-7012-2026-2-13-20
Abstract
Erythema nodosum (EN) is the most common type of septal panniculitis without signs of vasculitis. The clinical picture is characterized by painful erythematous nodules predominantly localized on the shins. Although the etiology of EN often remains unknown, the disease is based on a delayed-type hypersensitivity reaction to various antigenic stimuli. Since EN may be the first marker of a serious systemic disorder, ruling out a secondary nature of the disease is of fundamental importance. A wide range of possible etiological factors requires a thorough targeted evaluation of the patient to verify the diagnosis.
The authors present a diagnostic algorithm developed by them that will help optimize the initial assessment of patients with EN. Current approaches to the treatment of this condition are discussed.
Keywords
Supporting agencies: The article was prepared within the framework of the research project (state assignments № RK 125020501434-1 and RK 125020501433-4).
About the Authors
O. N. Egorova
V.A. Nasonova Research Institute of Rheumatology ; M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation
Russian Federation
Olga Nikolaevna Egorova
34A, Kashirskoe Shosse, Moscow 115522
61/2, Shchepkina Street, Moscow 129110
B. S. Belov
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
M. V. Datsina
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Russian Federation
Russian Federation
8, Trubetskaya Street, Build. 2, Moscow 119048
G. M. Tarasova
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
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Review
For citations:
Egorova ON, Belov BS, Datsina MV, Tarasova GM. Current concepts of erythema nodosum: from etiology to management strategy. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2026;20(2):13-20. (In Russ.) https://doi.org/10.14412/1996-7012-2026-2-13-20
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