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Современная ревматология

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Фармакотерапия люмбалгии

https://doi.org/10.14412/1996-7012-2014-2-95-102

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Аннотация

Неспецифическая боль в нижней части спины (БНЧС) – одно из самых распространенных ревматических заболеваний, с которым связано наибольшее число обращений за медицинской помощью. К сожалению, в нашей стране отсутствуют общепризнанная точка зрения на природу этой патологии и единая концепция ее терапии. Серьезной проблемой при ведении пациентов с БНЧС является неоправданно широкое применение дорогостоящих инструментальных методов диагностики и методов лечения с недоказанной и спорной эффективностью.

Основными препаратами для лечения БНЧС были и остаются нестероидные противовоспалительные препараты (НПВП). Их терапевтический потенциал доказан большим числом хорошо организованных клинических исследований и не вызывает сомнений. Вместе с тем появляются новые методы фармакотерапии БНЧС, такие как эпидуральное введение ингибиторов фактора некроза опухоли α, использование ингибиторов факта роста нервов и препаратов, влияющих на дисфункцию ноцицептивной системы. В статье рассмотрены основные группы лекарственных средств, которые нашли свое место или изучались при БНЧС: НПВП, парацетамол, опиоиды, миорелаксанты, антидепрессанты и антиконвульсанты, глюкокортикоиды, локальные анестетики, генноинженерные биологические препараты, представлены основные данные об их эффективности и переносимости. 

Об авторе

А.Е. Каратеев
ФГБУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой» РАМН, Москва, Россия


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Для цитирования:


Каратеев А. Фармакотерапия люмбалгии. Современная ревматология. 2014;8(2):95-102. https://doi.org/10.14412/1996-7012-2014-2-95-102

For citation:


Karateev A. Pharmacotherapy for lumbago. Modern Rheumatology Journal. 2014;8(2):95-102. (In Russ.) https://doi.org/10.14412/1996-7012-2014-2-95-102

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ISSN 1996-7012 (Print)
ISSN 2310-158X (Online)