Current state of diagnostic and treatment of osteoporosis in real-life clinical practice (a pilot study)
https://doi.org/10.14412/1996-7012-2014-2-58-62
Abstract
We report the results of a pilot study on physician awareness of modern diagnostic methods and drug therapy of osteoporosis (OP) and the use of this knowledge in daily practice.
A pilot survey among physicians demonstrated that experts (rheumatologists, endocrinologists, etc.) have a high level of awareness of the OP problem and successfully use this knowledge in daily practice (modern diagnosis, prevention, and treatment methods). They widely prescribe original drugs and certain generics that were shown to be effective in post-marketing surveillance.
Limitations of the study: 1) only physicians dealing with diagnosis and treatment of OP were surveyed; hence, the conclusions of this study are valid only for this group of physicians; 2) only physicians working in large cities who can use modern diagnosis methods (densitometry; determination of bone turnover markers) participated in the study; 3) Prolia medication, which has been used in Russia since 2013, was not taken into account in the questionnaire.
About the Authors
O.A. Nikitinskaya
V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, Russia
Russian Federation
Russian Federation
N.V. Toroptsova
V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, Russia
Russian Federation
Russian Federation
References
1. Cause-specific mortality, 2008: WHO region by country. Geneva: World Health Organization, 2011. Available from: http://apps.who.int/gho/data/node.main.887?lang=en
2. Марченкова ЛА, Древаль АВ, Крюкова ИВ. Информированность врачей различных специальностей в области остеопороза в московском регионе. Остеопороз и остеопатии. 2012;(1):11–4. [Marchenkova LA, Dreval AV, Kryukov IV. Awareness of physicians of various specialties of osteoporosis in the moscow region. Osteoporoz i osteopatii. 2012; (1):11–4. (In Russ.)]
3. Кузнецова ОЮ, Моисеева ИЕ. Изучение информированности врачей общей практики о проблеме остеопороза. Боль. Суставы. Позвоночник. 2012;3(07):15–7. [Kuznetsova OYu, Moiseeva IE. Studying of knowledge of general practitioners about an osteoporosis problem. Bol'. Sustavy. Pozvonochnik. 2012;3(07):15–7. (In Russ.)]
4. Лесняк ОМ. Аудит состояния проблемы остеопороза в странах Восточной Европы и Центральной Азии 2010. Остеопороз и остеопатии. 2011;(2):3–6. [Lesnyak OM. Audit of a condition of a problem of osteoporosis in countries of Eastern Europe and Central Asia 2010. Osteoporoz i osteopatii. 2011;(2):3–6. (In Russ.)]
5. Лесняк ОМ, редактор. Клинические рекомендации по профилактике и ведению больных с остеопорозом Российской ассоциации по остеопорозу. Ярославль: ИПК Литера; 2012. 24 с. [Lesnyak OM, editor. Klinicheskie rekomendatsii po profilaktike i vedeniyu bol'nykh s osteoporozom. Rossiiskaya assotsiatsiya po osteoporozu [Clinical recommendations about prevention and maintaining patients with osteoporosis of the Russian association on osteoporosis.]. Yaroslavl': IPK Litera; 2012. 24 p.]
6. Hansen C, Pedersen D, Konradsen H, Abrahamsen B. Anti-osteoporotic therapy in Denmark-predictors and demographics of poor refill compliance and poor persistence. Osteoporos Int. 2013;24(7):2079–7. DOI: 10.1007/s00198-012-2221-5. Epub 2012 Nov 22.
7. Black DM, Thompson DE, Bauer DC, et al. Fracture risk reduced with alendronate in women with osteoporosis. The fracture intervention trial. J Clin Endocrinol Metab. 2000;85(11):4118–24. DOI: http://dx.doi.org/10.1210/jcem.85.11.6953.
8. Торопцова НВ, Никитинская ОА. Лечение остеопороза: клинический опыт применения дженерического препарата. Современная ревматология. 2011;(1):28–32. [Toroptsova NV, Nikitinskaya OA. Treatment of osteoporosis: clinical experience in using a generic dru. Sovremennaya revmatologiya = Modern Rheumatology Journal. 2011;(1):28–32. (In Russ.)]. DOI: http://dx.doi.org/10.14412/1996-7012-2011-648.
9. Торопцова НВ, Никитинская ОА, Демин НВ и др. Результаты изучения эффективности еженедельного приема алендроната (Фосамакс®) у больных первичным остеопорозом. Остеопороз и остеопатии. 2006;(1):22–5. [Toroptsova NV, Nikitinskaya OA, Demin NV, et al. Results of studying of efficiency of weekly reception alendronate (Fosamax®) at patients with primary osteoporosis. Osteoporoz i osteopatii. 2006;(1):22–5. (In Russ.)]
10. Скрипникова ИА, Косматова ОВ, Новиков ВЕ и др. Результаты открытого многоцентрового исследования эффективности и переносимости Фосамакса 70 мг 1 раз в неделю при постменопаузальном остеопорозе. Остеопороз и остеопатии. 2005;(3):34–7. [Skripnikova IA, Kosmatova OV, Novikov VE, et al. Results of open multicenter research of efficiency and Fosamaks's shipping of 70 mg once a week at post-menopausal osteoporosis. Osteoporoz i osteopatii. 2005;(3):34–7. (In Russ.)]
11. Reymondier A, Caillet P, Abbas-Chorfa F, et al. MENOPOST – Calciumand vitamin D supplementation in postmenopausal osteoporosis treatment: a descriptive cohort study. Osteoporos Int. 2013;24(2):559–66. DOI: 10.1007/s00198-012-1999-5. Epub 2012 May 16.
12. Blotman F, Cortet B, Hilliquin P, et al. Characterization of patients with post-menopausal osteoporosis in French primary healthcare. Drugs Aging. 2007;24(7):03–14. DOI: http://dx.doi.org/10.2165/00002512-200724070-00007.
13. Lespessailles E, Cotto F-E, Roux C, et al. Prevalence and features of osteoporosis in the French general population: the Instant study. Joint Bone Spine. 2009;76(4):394–400. DOI: 10.1016/j.jbspin. 2008.10.008. Epub 2009 Mar 17.
14. Fardellone P, Mann B. Co-prescription of calcium and/or vitamin D with once weekly bisphosphonate therapy: findings from a French longitudinal patient database. Osteoporos Int. 2007;18 (Suppl. 1):358.
15. Adami S, Giannini S, Bianchi G, et al. Vitamin D status and response to treatment in post-menopausal osteoporosis. Osteoporos Int. 2009;20(2):239–44. DOI: 10.1007/s00198-008-0650-y. Epub 2008 Jun 13.
Review
For citations:
Nikitinskaya O, Toroptsova N. Current state of diagnostic and treatment of osteoporosis in real-life clinical practice (a pilot study). Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2014;8(2):58-62. (In Russ.) https://doi.org/10.14412/1996-7012-2014-2-58-62
Views:
1342
Email this article 