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Specific features of comorbidity in rheumatoid arthritis patients in different follow-up years

https://doi.org/10.14412/1996-7012-2015-1-39-41

Abstract

Objective: to study the rate and pattern of comorbidities in two groups of patients with rheumatoid arthritis (RA) in different follow-up years.

Subjects and methods. The pattern of comorbidity was investigated in RA patients treated at the Rheumatology Unit, Saratov Regional Clinical Hospital, in different follow-up years. The investigation enrolled patients treated with disease-modifying antirheumatic drugs (DMARDs) in a stable dose for 3 months or longer. The patients were interviewed and objectively examined and the data of their outpatient medical records were taken into consideration. Group included 201 patients examined in 2006–2007. Group 2 comprised 328 patients examined in 2012–2013.

Results. Comorbidities were ascertained in 67.2% of the patients in Group 1 and in 86.6% of those in Group 2. Two to five co-occurring diseases were more common in the examinees in 2012–2013 (66.9%) than in those in 2006–2007 (57%). The patients of both groups were most frequently found to have hypertension (60 and 57.7% of the patients, respectively) and osteoarthritis (OA) (71.1 and 50.7%). Out of the other diseases, the patients were most commonly found to have gastrointestinal tract (GIT) diseases (97.8 and 80.3%, respectively) and urinary tract infections (22.4% and 19.7%).

Conclusion. The rate of comorbidities remains high in patients with RA. Among the comorbid diseases, there is a preponderance of hypertension, GIT diseases, and OA.

About the Authors

N. M. Nikitina
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia
Russian Federation
112, B. Kazachya St., Saratov 410012


I. A. Afanasyev
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia
Russian Federation
112, B. Kazachya St., Saratov 410012


T. A. Romanova
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia
Russian Federation
112, B. Kazachya St., Saratov 410012


A. P. Rebrov
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia
Russian Federation
112, B. Kazachya St., Saratov 410012


References

1. Верткин АЛ, Румянцев МА, Скотников АС и др. Коморбидность. Вестник семейной медицины 2011;(3):40–7. [Vertkin AL, Rumyantsev MA, Skotnikov AS, et al. Comorbidity. Vestnik semeinoi meditsiny 2011;(3):40–7. (In Russ.)].

2. Гордеев АВ, Галушко ЕА, Насонов ЕЛ. Концепция мультиморбидности в ревматологической практике. Научно-практическая ревматология. 2014;52(4):362–5. [Gordeev AV, Galushko EA, Nasonov EL. The concept of multimorbidity in rheumatologic practice. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2014;52(4):362–5. (In Russ.)]. doi: http://dx.doi.org/10.14412/1995-4484-2014-362-365.

3. Панафидина ТА, Кондратьева ЛВ, Герасимова ЕВ и др. Коморбидность при ревматоидном артрите. Научно-практическая ревматология. 2014; 52(3):283–9. [Panafidina TA, Kondrat'eva LV,

4. Gerasimova EV, et al. Comorbidity in rheumatoid arthritis. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2014;52(3):283–9. (In Russ.)]. doi: http://dx.doi.org/10.14412/1995-4484-2014-283-289.

5. Балабанова РМ, Эрдес ШФ. Ревматические заболевания у взрослого населения в федеральных округах России. Научно-практическая ревматология. 2014;50(1):5–7. [Balabanova RM, Erdes ShF. Rheumatic diseases in the adult population in federal districts of Russia. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2014;50(1):5–7. (In Russ.)]. doi: http://dx.doi.org/10.14412/1995-4484-2014-5-7.

6. Boers M, Dijkmans B, Gabriel S, et al. Making an impact on mortality in rheumatoid arthritis. Targeting cardiovascular comotbidity. Arthritis Rheum. 2004 Jun;50(6):1734–9. doi: 10.1002/art.20306

7. Ward MM. Recent improvements in survival in patients with rheumatoid arthritis: better outcomes or different study design? Arthritis Rheum. 2001 Jun;44(6):1467–9. doi: 10.1002/1529-0131(200106)44:6<1467::AIDART243>3.0.CO;2-6

8. Мясоедова ЕЕ. Роль традиционных факторов риска, хронического аутоиммунного воспаления и фармакотерапии в развитии кардиоваскулярных нарушений при ревматоидном артрите. Вестник Ивановской медицинской академии. 2013;18(1):57–64. [Myasoedova EE. The role of traditional risk factors, chronic autoimmune inflammation and pharmacotherapy in the development of cardiovascular disorders in rheumatoid arthritis. Vestnik Ivanovskoi meditsinskoi akademii. 2013;18(1):57–64. (In Russ.)]

9. Osiri M, Sattayasomboon Y. Prevalence and out-patient medical costs of comorbid conditions in patients with rheumatoid arthritis. Joint Bone Spine. 2013 Dec;80(6):608–12. doi: 10.1016/j.jbspin.2013.01.013. Epub 2013 Jul 1. doi: 10.1016/j.jbspin.2013.01.013.

10. Charlson ME. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83. doi: http://dx.doi.org/10.1016/0021-9681(87)90171-8.

11. Sattar N, McCrey DW, Capell H, McInnes IB. Explaining how «high-grade» systemic inflammation accelerated vascular risk in rheumatoid arthritis. Circulation. 2003 Dec 16;108(24):2957–63.

12. Maradit-Kremers H, Nicola PJ, Crowsoon CS, et al. Cardiovascular death in rheumatoid arthritis. Arthritis Rheum. 2005 Mar;52(3):722–32. doi: 10.1002/art.20878

13. Попкова ТВ, Новикова ДС, Насонов ЕЛ. Атеротромбоз при аутоиммунных заболеваниях: современное состояние проблемы. Consilium medicum. 2008;10(11):128–35. Popkova TV, Novikova DS, Nasonov EL. Aterotromboz at autoimmune diseases: current state of a problem. Consilium medicum. 2008; 10(11):128–35. (In Russ.)].

14. Lеvy l, Fautrel B, Barnetche T, Schaeverbeke T. Incidence and risk of fatal myocardial infarction and stroke events in rheumatoid arthritis patients. A systematic review of the literature. Clin Exp Rheumatol. 2008 Jul–Aug;26(4):673–9.

15. Kadam UT, Jordan K, Croft PR. Clinical comorbidity in patients with osteoarthritis: a case-control study of general practice consulters in England and Wales. Ann Rheum Dis. 2004 Apr;63(4):408–14. doi:http://dx.doi.org/10.1136/ard.2003.007526.

16. Jebakumar AJ, Udayakumar PD, Crowson CS, Matteson EL. Occurrence of gout in rheumatoid arthritis: it does happen! A population-based study. Int J Clin Rheumtol. 2013 Aug;8(4):433–7.

17. Franklin J, Lunt M, Bunn D, et al. Risk and predictors of infection leading to hospitalisation in a large primary-care-derived cohort of patients with inflammatory polyarthritis. Ann Rheum Dis. 2007 Mar;66(3):308–12. Epub 2006 Sep 19. doi:10.1136/ard.2006.057265


Review

For citations:


Nikitina NM, Afanasyev IA, Romanova TA, Rebrov AP. Specific features of comorbidity in rheumatoid arthritis patients in different follow-up years. Sovremennaya Revmatologiya=Modern Rheumatology Journal. 2015;9(1):39-43. (In Russ.) https://doi.org/10.14412/1996-7012-2015-1-39-41

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ISSN 1996-7012 (Print)
ISSN 2310-158X (Online)