Факторы, определяющие длительный успех терапии генно-инженерными биологическими препаратами при ревматоидном артрите
Аннотация
Необходимость достижения клинической ремиссии или низкой активности болезни у каждого пациента с ревматоидным артритом подчеркивает важность комбинированной терапии с включением метотрексата и генно-инженерных биологических препаратов в случаях резистентности к обычным базисным противовоспалительным препаратам. Современные требования подразумевают не только достижение результата, но и его длительное (многолетнее) сохранение. Возможность достижения стабильных результатов лечения определяется сочетанием многих факторов, таких как клиническая эффективность, безопасность, низкая иммуногенность, возможность длительного применения и экономическая целесообразность. Анализ данных литературы за последние 5 лет позволяет сделать вывод, что ингибитор фактора некроза опухоли этанерцепт обладает оптимальным сочетанием этих параметров.
Об авторе
Дмитрий Евгеньевич Каратеев
ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия
115522, Москва, Каширское шоссе, 34А
Россия
115522, Москва, Каширское шоссе, 34А
Литература
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Для цитирования:
Каратеев Д.Е. Факторы, определяющие длительный успех терапии генно-инженерными биологическими препаратами при ревматоидном артрите. Современная ревматология. 2015;9(3):54-60. https://doi.org/10.14412/1996-7012-2015-3-54-60
For citation:
Karateev D.E. Factors determining long-term success of biologic therapy in rheumatoid arthritis. Modern Rheumatology Journal. 2015;9(3):54-60. (In Russ.) https://doi.org/10.14412/1996-7012-2015-3-54-60
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